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Volume 8 Articles

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Volume 8 Articles

The Role of Bone Mineral Density Assessment in Health-Related Quality of Life in Postmenopausal Han Chinese Women Prior to Clinic Diagnosis of Osteoporosis

Osteoporosis is a systemic skeletal disease and strongly associated with reduced quality of life (QoL). The aimof the study was to explore BMD that......

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Unerupted Teeth, A New Symptom of Amyloidosis?

Amyloidosis are rare diseases related to the pathological aggregation and accumulation of misfolded proteins in the extracellular space generating insoluble deposits. This may occur in almost any tissue and organ, leading to severe structural damages and functional impairments.......

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Commentary: Defecation Delay in Patients After Lung Tumor Surgery: AProspective Nested Case-Control Study

This is a brief commentary to our article “Defecation delay in patients after lung tumor surgery: a prospective nested case-control study” [1]. The author Chen used to be a resident and rotate in different departments......

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After Sequential Therapy with First and Third Generation EGFR-Tkis, A Patient Acquired EGFR G719A Mutation and Responded to Afatinib, and Then, Acquired EGFR T790M Mutation When Developed Resistance to Afatinib: A Case Report

NSCLC patients who had sensitive EGFR mutation had great possibility to get benefit from EGFR-TKIs. But this efficacy was relied on related EGFR mutation, if related EGFR mutation changed, resistance would happened.......

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SARS-Cov2 and limb Ischemia

Patients with severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) infection mainly present severe pneumonia associated with complication srelated tocytokinestormsyndrome. So, it was associated with thromboti cincidents like a cutelimbischemia and pulmonary embolism.......

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A Road from Coronary to Pulmonary: A Rare Imaging Presentation

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Its association with Pulmonary Atresia is considered to be the most severe form, the diagnosis of which plays an important role in determination of the......

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Prevalence and Determinants of Distress Among Residents During COVID Crisis

Residents are predisposed to develop distress, burnout, and depression. With COVID-19, new stressful working conditions were imposed. This study aims to assess the impact of COVID-19 on residents’ wellbeing in France.......

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Ulcerative Colitis with Aseptic Abscesses Controlled by Vedolizumab: A Case Report

Aseptic abscesses (AAs) are neutrophilic infiltrative lesions that often coincide with systemic inflammatory disorders such as inflammatory bowel diseases (IBD). According to recent literature, medical therapies in IBD with AAs include co......

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A Metastatic Melanoma Patient with Spontaneous Melanoma Associated Vitiligo Survived for up to 7 Years and 5 Months: A Case Report

Malignant melanomaisa highly malignant tumor caused by abnormal proliferation of melanoma cells in the skin and mucous membranes, with apoorprognos is after metastasis.......

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Giant Gallstone, Rare Cause for Conversion to open Cholecystectomy from Laparoscopic

Gallb ladder stones is one of the most common disease of the digestive system. Giantgallb ladder stoneisrare and subject to technical difficulties in laparoscopic cholecystectomy with high rate of conversion to open cholecystectomy.......

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Quality of Life, After Bariatric Surgery

Obesity is a disease characterized by the abnormal accumulation of body fat. It is estimated that there are 650 000 000 obese adults. Its incidence has increased in recent years, contributing to the decrease in the average life expectancy......

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Conservative Treatment of Retained Placentas: A Report of Two Cases

To demonstrate conservative treatments for retained placenta accreta in puerperants who underwent induced labour of dead foetuses in the second trimester......

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Radiation Therapy of Thyroid-related Eye Diseases

Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease associated with thyroid-related posterior ocular and perimeter orbital tissue invasive lesions......

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Management of Prolapsed End Transverse Colostomy: A Simple Local Revision

Prolapsed colostomy is a well-known complication, occurring with transverse colostomies more frequently than other types of colostomies. It is usually managed conservatively when it is uncomplicated; however......

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Herniation of the Ovary into the Canal of Nuck in a 3 Month Old Female Infant: A Rare Entity Needing Urgent Ultrasonography Evaluation

Indirecting uinalhernia of the canal of Nuck containing the pelvic organs such as ovary is a rare entity among females of pediatric age group which presentsass welling of labiamajora. It iscaused by congenitally failedclo sure of the process usvaginalis in female......

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Endovascular Treatment of Common Iliac Artery Aneurysm after open Repair for RupturedAAAwith Commercially Available Devices in Bulgaria - Case Report

True iliac aneurysms development is a major sign of an eurysmdisease progression after open repair for Abdominal Aortic Aneurysm (AAA). We present our experience in en- dovascular repair of true iliac aneurysm after open reconstruction ......

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Spontaneous Pneumomedia stinum with Subcutaneous Emphysemaina COVID-19 Patient

A 39-year-old man presented to the emergency room with complaints of fever, shortness of breath and pronounced dry coughfor 1 week. On physical examination, his respiratory rate was 28 breaths/min and his oxygen......

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Sub-Dural Hematoma and COVID-19 Infection: Re-Bleeding Following Anti-Coagulation

Chronic subdural hematoma generally occurs in elderly patients. Anti-coagulation is also a frequent risk factor for this disease. The objective of thisreport was to present the rare case of a right hemispheric subdural hematoma associated with......

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Editorial

Let me starts with short explanation which led me to write these words to encourage all of you who had experienced or are still experiencing the problem and situation I had gone through. One eveningjust talking with ......

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Bio-Statistics Newer Advances, Scope & Challengesin Bio-Medical Research

Biostatistics also known as biometry which means ‘measurement oflife’ is abranch of applied statistics which deals with collection, compilation, analysis and interpretation of data related to biomedical sciences.......

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Cross-Sectional Study on Prevalence of Psychological Comorbidity in Patients with Psoriasis

This study investigates the prevalence of psychological comorbidity in patients with moderate to severe psoriasis vulgaris. Furthermore, the relation between the type of disorder and the degree of psoriasis severity has been analysed.......

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A Giant Multifocal Squamous Cell Carcinoma Arising in a Patient with Hidradenitis Suppurativa

Few reports describe squamous cell carcinoma arising in hidradenitis suppurativa. Although rare, the combination of SCC and HS is often associated with early metastasis and high mortality rates.......

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Treatment of Deep Burn Wounds of the Buttocks and perineum using Vacuum Sealing Drainage Combined with a Homemade Anal Canal

The aim of this study was to investigate the therapeutic effects of vacuum sealing drainage technology combined with homemade anal canal treating the deep burn wounds of the buttocks and perineum. From March ......

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Prevelance of Ovarian Cancer and Its Corelation with Age in Pakistan

Group of diseases that is originated from the different parts of ovaries and cause production of abnormal cells that divide uncontrolled themselves in the ovaries is known as ovarian cancer.......

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Tuberculosis: A Rare Cause of Linear Labial Ulceration

Oral location of tuberculosis is rare. It admits a clinical polymorphism and poses above all a problem of diagnosis. We report a caseoflabialtuberculosisina16-year-old patient with underlying lymph node localization......

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Management of Acid Base Disorders in Pregnant Woman

The interpretation of the acid-base statusis key in medical practice, being its most frequent use in critically ill pregnant patients with any type of hemodynamic alteration such as hemorrhagic shock or septic shock, which happens......

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Computerized Misinterpretation of QT Interval in 12-Lead Electrocardiogram and Its Clinical Consequences:ACase of Recurrent Syncope

The diagnosis of long QT syndrome may be delayed due to absenceofelectrocardiogram(ECG)examinationand/orQTinterval misdiagnosis. We present......

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Extraperitoneal end Tunnel Colostomy Before the Posterior Sheath of the Abdominal Poster Rectus Muscles: A Novel Surgical Technique to Reduce the Incidence Of Hernia

Parastomal hernia is one of the most common complications after colostomy. Preventive strategies are considerable. For less defect and better mechanical work......

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Clay-Shoveler’s Fracture Caused by Long-Term Bad Posture and Bad Habits: A Case Report

To discuss the fracture of the spinous process of the lower cervical vertebra and upper thoracic vertebra due to long-term bad posture and bad habits, called Clan-Shoveler's fracture. Methods: To analyze the ......

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Severe Respiratory Failure from SARS COV 2, Complicated with Pneumothorax in a Pregnant Woman: A Case Report

The first data for COVID-19 in pregnancy showed mild to moderate forms of the disease while current data speaks of severe forms in these subjects. Here we present a case of a severe form of COVID-19 in a gemelar pregnant woman complicated with pneumomediastin and pneumothorax, during her hospital stay, in a late stage of disease.......

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The Role of Cellular Immunity in the Protective Efficacy of the SARS-Cov-2 Vaccine

Several severe acute respiratory Syndrome Coronavirus 2 (SARSCoV-2) vaccines have been approved for clinical use. However, most studies use the SARS-CoV-2-neutralizing antibody titers induced after immunization......

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Cardiac Myxoma: A Rare Case Series of 4 Patients and a Literature Review

Cardiac myxomas are the most common primary cardiac tumor. Clinical findings are numerous and range from general manifestations to symptoms related to......

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Evaluation of a Simulation Program for Management of Cardiovascular Emergencies in Pregnant Women

Medical education worldwide is undergoing a pedagogical renovation movement; medical simulation is one of the revolutionary educational tools whose aim is to improve the medical knowledge,.....

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Structure and development of a clinical decision support system: application in high Digestive Gastroenterology

Clinical decision requires to infer great, diverse and not suitably organized quantity of information and having low time to decide. The therapeutic choice is fundamental to formulate a strategy to avoid complications and to......

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Rectal Cancer Watch and Wait Approach: A Promising Rectal Salvaging Strategy

Colorectal cancer is the third most common cancer worldwide, with rectal cancer being the 10th fatal cancer. The current recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy......

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COVID-19 Associated Loss of Smell and Taste Treated with Gabapentin

Throughout the COVID-19 Pandemic, the symptoms of loss of smell and taste have been commonly encountered by healthcare professionals, and in fact, have become an important screening tool. By some estimates,......

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Giant Cell Tumor of the Middle Phalanx of Ring Finger Treated with Wide Excision and Reconstruction using Non-vascularized Fibular Graft: A Rare Case Report and Review of Literature

Giant cell tumor (GCT) involving the hand, specifically the phalangeal bones, is very rare, accounting for only 2% of cases of the bone. This type......

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Metastatic Adrenocortical Carcinoma Presenting as Intracavitary Mass in Right Atrium: A Case Report

Adrenocortical carcinomas grow rapidly and tend to metastasize to liver and lungs and invade kidney, renal vein and Inferior vena cava (IVC). Cardiac metastases of the tumor is rare, less than 20 cases have......

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Multistrand Titanium Cable Combined with AO Metacarpal Plate in Treating Acromioclavicular Dislocation

As far as we know, no literature is available regarding multistrand titanium cable (MSTC) combined with AO metacarpal plate in treating acromioclavicular (AC) dislocation. Therefore, the current study aimed to evaluate the clinical results of applying such technology in treating AC dislocation. ......

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Congenital Panfollicular Nevus

A 1-month-old girl presented to our dermatology clinic with a few irregular asymptomatic nodules on her scalp which were present at birth and had recently increased in size. An incisional biopsy was taken, and the results were compatible with a newly proposed entity called congenital panfollicular nevus.......

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Bone Metastasis as Initial Presentation of an Aggressive Adenoid Cystic Carcinoma of Mandible: Case Report

Adenoid cystic carcinoma (ACC) is a slowly growing malignant neoplasm with possible widespread distant metastasis. The diagnosis requires thorough ......

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Intra-Abdominal Lymphangioma

Lymphangiomas are rare slowly growing benign tumors derived from lymphatic vessels. They occur in various anatomical locations of body like head,......

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COVID-19 Pneumonia in a Congenital Adrenal Hyperplasia; A Case Report

Congenital Adrenal Hyperplasia (CAH) is managed with longterm corticosteroid and is suggested to higher dose, based on the general sick day principles.......

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Management of Shunt complication in a Paediatric COVID 19 Case in Bangladesh Medical College Hospital

V-P shunt is the most common surgery done in paediatric hydrocephalus. Though the surgery remains as ‘minor’ in the arena of Neurosurgery, its complication......

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Emergencies in Parkinsonism

Patients with Parkinsonism may present acutely to the ED with serious and even life-threatening conditions. Although falls are a common presentation in advanced Parkinsonism, early presentations with......

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Rare Bullous Pemphigoid During PD-1 Inhibitor Therapy: A Case Report

Immunotherapy is an important treatment modality in cancer, but it can also cause adverse reactions, with skin toxicity being the most common. The increasing number of immune checkpoint inhibitors being used in the clinic will inevitably cause an increase in the rate of adverse skin......

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Uncommon Site for Deep Vein Thrombosis in a Kidney Transplant Recipient After Switching Tacrolimus to Sirolimus: A Case Report

We report a 67-year-old male patient who underwent a living related kidney transplantation from his daughter. He developed New-onset Diabetes after Transplantation (NODAT). Sirolimus was introduced and Tacrolimus was stopped to avoid recurrence of......

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NF1 Mutated Metastatic Melanoma and Response to Immune Checkpoint Inhibitor Therapy: A Retrospective Analysis

Based on molecular profiling, malignant melanoma is classified in four different groups. NF1-mutated tumors are a small subgroup occurring with a frequency of 13% of all malignant melanomasd recurrent irritation of the bladder. Because of its. ......

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Young Women with Relapse of Acute Lymphoblastic Leukemia Mimicking the Myomatous Uterus

Case presenation of a rare clinical manifestation of a relapse of acute lymphoblastic leukemia in a young woman manifested by growing uterus mimicking a myomatous uterus.......

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Four Unique Laboratory Characteristics Applied to Assess the Severity of COVID-19

The sudden outbreaking of COVID-19 worldwide has brought into sharp increased burden of economic and treatment. How to simply, quickly and accurately assess the severity of patients with COVID-19 in the early stage after hospital admission is essential for healthcare systems. ......

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Cystitis Glandularis: A Case Report of a Rare Benign Bladder Tumor

Pseudotumor or florid cystitis glandularis is the bladder urothelial of the which mainly affects humans [1,2,3]. It is facilitated by chronic and recurrent irritation of the bladder. Because of its. ......

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Oral Minocycline Challenge as a Potential First-Line Therapy for Myalgic Encephalomyelitis and Long Covid-19 Syndrome

Chronic fatigue syndrome characterized by severe disabling fatigue, prolonged post-exertional malaise, and unrefreshing sleep markedly reduces the activities of daily living and impairs the quality of life. ......

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Personnel Policy and Practice: Sustainable Management of Pharmacy, Pharmacists and Pharmaceuticals and How to Bridge the Gap in Human Resources for Health

Worldwide there are different systems for providing pharmacy services. Most countries have some element of state assistance, either for all patients or selected groups such as children, and some private provisions.......

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Genetic Polymorphic Impact of Metabolizing Enzyme (CYP3A4 and UGT1A4 genes) on Anastrazole Response in Iraqi Breast Cancer Women

Anastrazole is an aromatase inhibitor used widely in therapy of breast cancer and has been metabolized by CYP3A4 and UGT1A4 in liver. Breast cancer is the most common cancer type in worldwide and the second causes of death after lung cancer and the......

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Concomitant Diseases in a Complex Case of Peritonitis after Stapled Trans Anal Rectal Resection (Starr) in Obstructed Defecation Syndrome (Ods). Role of a Diagnostic and Therapeutic Multidisciplinary Approach

Approximately 0.06-2.3% of the population presents a Jejunal and Ileal Diverticular (JID) disease, of whom approximately 10% develop life-threatening complications such as inflammation, perforation, bleeding......

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Mucoepidermoid Carcinoma of Parotid Gland: 2 Cases and Literature Review

Mucoepidermoid Carcinoma (MEC) of the salivary gland accounted for 5% of all salivary gland tumors and 20% of all malignant salivary gland tumors [1]. About 50% of salivary gland Mucoepidermoid carcinoma......

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A Case of Giant Intrapericardial Teratoma of the Heart in an Infant with a Favorable Outcome

Primary cardiac tumors in newborns and young children are rare, but they affect significantly their health and can be the cause of sudden death. These tumors compromise the integrity and function of adjacent c......

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Schwannoma With Extensive Vascular Hyperplasia in the Breast Mimicking Angiosarcoma

Schwannoma with extensive vascular hyperplasia in the breast is extremely rare. It is typically benign and slow growing. Here, we describe a case of 54-year-old woman underwent complete resection of a tumor measuring 2.5×2.0 cm in the breast. The tumor was composed with......

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Diffuse Cystic Airspaces in Bilateral Lungs Caused by Anlotinib

A 31-year-old woman, who was diagnosed of stage IVB pulmonary adenocarcinoma in July, 2018, accepted first-line treatment of afatinib and second-line treatment of platinum-based doublet chemotherapy.......

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Solitary Gastric Metastasis of Breast Invasive Lobular Carcinoma

A 52-year-old female patient with solitary gastric metastasis from breast invasive lobular cancer without any other organ involvement is presented in this study......

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Mandibular AV Malformation: Life-Threatening Bleeding from the Mouth Managed by Endovascular Intervention Complicated by Acute Ischemic Stroke on Table. Case Report

Arteriovenous malformations (AVM) of mandibula are rare abnormal congenital vascular condition that can result in serious complications. Although, various treatment options have been advocated in the literature,......

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Laparoscopic Resection of Large Endo-Cervical Polyp Through Posterior Colpotomy as an Alternative Access to Vagina in Virgin Patients

Endometrial polyps have been involved in about 50% of patients with abnormal uterine bleeding and 35% of infertile patients. Management of pedunculated end ocervical myoma or polyp normally requires intervention ......

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A Typical Lateral Medullary Syndrome

Lateral medullary syndrome (LMS) is a type of ischemic stroke which occurs due to disruption of the blood flow in vertebral artery, or posterior inferior......

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Repeated Hemoptysis With Progressive Bronchiectasis: A Case Report of Lady Windermere Syndrome

Bronchiectasis is a type of incurable structural lung disease with clinical manifestations of chronic cough, expectoration or recurrent hemoptysis, which is often given anti-infection and symptomatic treatment. In this study, a patient suffering from bronchiectasis with repeated hemoptysis caused......

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Papillomavirus Vaccines Among University Students In Angola

Cervical cancer is the first most common cancer among women in Angola and accounts for 37.6% of cancers among women in Angola. The human papillomavirus (HPV) is a causative agent of the disease.,......

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Floating Thrombi in The Right Ventricular Outflow Tract

A 51-year-old woman was admitted to the hospital for an intermittent syncope. No abnormal findings on physical examination. Laboratory results showed B-type brain natriuretic peptide......

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Implementing SPADE Protocol (Save Patient from Pain, Agitation and Delirium, Execution Protocol) to Decrease the Incidence of ICU Delirium

This is a proposal for a multidimensional, multidisciplinary protocol pathway model that was dubbed SPADE. Due to pain, agitation, delirium magnitude (PAD) and its effect in intensive care on mechanically ventilated patients,......

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Statin as A Cause Immune-Mediated Necrotizing Myopathy: Case Report and Narrative

Statin-induced immune-mediated necrotizing myopathy (IMNM) is an exceedingly rare complication of statin use, which should be suspected in the patient with elevated CPK levels, symmetric proximal muscle weakness and persistence of symptoms despite discontinuation of statin therapy.......

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Euglycemic Ketoacidosis and an Absence Seizure in A Type 2 Diabetic On SGLT2 Inhibitors: Case Report and Review of the Literature

In recent years, many new antidiabetic drugs have been developed. One class of these new antidiabetic drugs are sodium-glucose cotransporter 2 inhibitors (SGLT2i). SGLT2i are associated with an increased ......

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Ankle Malignant Peripheral Nerve Sheath Tumor in A Neurofibromatosis I Patient: A Case Report and Review the Literature

Malignant Peripheral Nerve Sheath Tumors (MPNST) are rare and aggressive sarcomata’s tumors with an overall incidence of 0.001% [1] derived from Schwann cells or pluripotent cells of the neural crest [2-8]. MPNSTs are typically seen in patients aged 20-50 years,......

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A Case of Mycobacterium Abscessus in an Immunocompetent Patient

A 71-year-old lady from the USA, presented with a four-week history of cough and dyspnoea with a cavitatory lesion on her chest x-ray.......

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Body Mass Index and Postoperative Outcomes of Patients with Laparoscopic Adrenalectomy. A Single Center Experience

Laparoscopic adrenalectomy has become the standard of care for resection of adrenal masses with extremely low morbidity and mortality. This study investigates the difference in outcomes in patients who underwent laparoscopic adrenalectomy, comparing obese with non-obese patients.......

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Therapeutic Challenges in Post-Transplant Lymphopro lif erative Disorder of the Esophagus with Central Nerve System Involvement Complicated by an Esophagotracheal Fistula: A Case Report

Post-transplant lymphoproliferative disorder (PTLD) is a known complication following solid organ or hematopoietic stem cell transplantation. It’s a heterogeneous group of lymphoid and/or plasmocytic proliferations as a result of immunosuppression and is frequently......

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Clinical Symptoms are Better Than CT Images for Treatment Evaluation and Hospital Discharge in Patients with Coronavirus Disease 2019 (COVID-19)

To determine whether changes in CT are better than clinical symptoms for treatment evaluation, and whether CT is necessary to determine the discharge of patient undergoing COVID-19 treatment.......

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Janeway Lesions as The Primary Sign of an Infected Radial Artery Aneurysm After Cannulation

A 52-year-old man with subarachnoid hemorrhage (Fisher 2, World Federation of Neurosurgical Societies Grading Scale 1) underwent endovascular coiling and was admitted to the intensive care unit for standard......

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Effect of Preoperative Chemotherapy and Postoperative Adjuvant Chemotherapy for Gastric Cancer with Positive Peritoneal Lavage Cytology (CY1): A Retrospective Study

Peritoneal metastasis is one of the most common forms of metastases for gastric cancer [1]. The 15th edition of the Japanese Classification of Gastric cancer defines patients with positive peritoneal lavage cytology ......

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Prevalence and Predictors of Self-Medication in the Younger Elderly of Ahvaz Based on Protection Motivation Theory

The use of medicines is one of the main parts of the treatment of diseases. However, self-medication can be followed several complications. The aim of this study was determine the prevalence and factors influencing self-medication based on protection motivation theory (PMT)......

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