Annals of Clinical and Medical Case Reports
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Annals of Clinical and Medical Case Reports is a peer-reviewed journal that publishes original case reports covering various medical specialties. The journal aims to provide valuable insights and information on rare and interesting cases to help healthcare professionals improve patient care and outcomes.
Case studies give an indicate of the decision-making process so that other physicians can apply lateral thinking to their own cases. These speak to a significant, opportune and significant examination configuration in propelling clinical logical information, particularly of uncommon illnesses.
The publication of latest and emerging information in such a way to pave the platform for reporting of unique, unusual and rare cases enhance understanding of the disease process.
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Recent Articles
Clinical Reasoning and Artificial Intelligence: A Transformative Synergy
Clinical reasoning is fundamental in medical practice but faces significant challenges due to the increasing complexity and volume of medical information.....
View PDF View FulltextTuberculous Otitis Media With Incompletely Recovered Facial Paralysis – A Case Report
Tuberculous otitis media (TOM) is rare and difficult to diagnose because of its low incidence and low suspicion. We experienced the patient with otorrhea and facial palsy and performed unnecessary operation because of delayed diagnosis with low suspicion. We report this case for the purpose of being helpful to other clinicians. ....
View PDF View FulltextPregnancy and Neonatal Outcomes in Patients with Paroxysmal Nocturnal Hemoglobinuria: A Case Series with Review of the Literature
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder marked by intravascular hemolysis resulting from somatic cell mutations. The condition poses elevated risks of maternal and neonatal morbidity and mortality, w....
View PDF View FulltextAccessory Cardiac Bronchus and Cervical Rib
IWe present a 70-year-old male, former smoker of 68 pack-years, without any other relevant personal or surgical history, nor any known allergies. He worked as a banana tree farmer. He came to our Pneumology....
View PDF View FulltextPrognostic Nutritional Index (PNI) In Patients With Severe Encephalitis As A Useful Prognostic Indicator: A Multivariate Analysis
The prognostic impact of poor nutritional status in severe encephalitis is not clearly understood. We aim to investigate the relationship betweenthe prognostic nutritional index (PNI) and poor outcomes of severe encephalitis. ....
View PDF View FulltextAdvancing Clinical Insights: The Critical Role Of Detailed Case Reports In Modern Medicine
In the ever-evolving landscape of clinical medicine, the significanceof case reports cannot be overstated. They serve as the building blocks of medical knowledge, offering valuable insights into rare conditions, unique presentations,...
View PDF View FulltextStreptococcus Mitis Group Infections: Epidemiology, Antibiotic Susceptibility Profile And Risk Factors Evaluation
To assess the epidemiological, clinical characteristics of Streptococcus mitis group (SMG) infections, their drug resistance profile, and their relative risk and prevalence for...
View PDF View FulltextTraumatic Cataracts: Focus On Rosette-Shaped Cataracts
Traumatic Cataract Is a serious and common condition that mainly affects young adults and children. We report the case of a 25-year-old femalepatient who presented for consultation with blurred vision that had...
View PDF View FulltextModern Approaches To Non-Specific Prevention Of Viral Respiratory Infections
Global urbanization and the events of the COVID-19 pandemic have revealed problems related to the consequences of disturbed ecology and weakened immunity of residents of megacities. According to experts of the International Monetary Fund, the financial losses of the global economy...
View PDF View FulltextRetrograde Type A Aortic Dissection Following Thoracic Endovascular Aortic Repair
Retrograde Type A aortic dissection is a rare but potentially life-threatening complication of thoracic endovascular aortic repair (TEVAR). A 61-yearold man presented with...
View PDF View FulltextEffect Of Stopping Antiplatelet Therapy On Stent Thrombosis In Patients With Coronary Stents
In recent years, the introduction of drug-eluting stents(DES) in PCIs (Percutaneous Coronary Interventions) for coronary...
View PDF View FulltextA Male Patient with Spontaneous Coronary Artery Dissection and A Bicuspid Aortic Valve
Spontaneous coronary artery dissection (SCAD) is a rare and emergent condition where a tear in the intimal portion of the coronary artery produces ischemia to the myocardium...
View PDF View FulltextCongenital Pigmented Nevus With Skin Ossification (Nanta Nevus): A Case Report
Bone formation or ossification in skin is a rare phenomenon that may be primary or secondary. Primary cutaneous ossification is mainly seen in Albright hereditary ...
View PDF View FulltextThe Therapeutic Potential Of Short Chain Fatty Acids In Elderly Type 2 Diabetes Patients With Sarcopenia
The correlation between short-chain fatty acids (SCFAs) in the intestinal flora and sarcopenia in patients with type 2 diabetes is a topic of growing interest in recent research...
View PDF View FulltextA Rare Case Report Of Hyperparathyroidism With Multiple Osteolytic Lesions Misdiagnosed As Multiple Myeloma
Hyperparathyroidism with diffuse bone lesions is relatively rare, typically manifesting with symptoms such as bone pain or pathologic fractures. Due to the lack of understanding of this disease, these extensive lytic lesions are often misdiagnosed...
View PDF View FulltextPulmonary Brucellosis In A Patient With Prolonged Dyspnea And Cough
Brucellosis is a bacterial endemic zoonotic disease of global significance with detrimental impacts on public health and food animal production. It is caused by Brucella spp., an expanding group of pathogens able to infect various host species...
View PDF View FulltextDo Placement Of Orthodontic Mini-Implants In Different Locations Improve Skeletal Effects In Herbst Appliance
The aim of this study is to compare dental and skeletal effects in Herbst appliance treatment without anchorage, with interradicular skeleta...
View PDF View FulltextThe Significant Efficacy of Botulinum Toxin for Deafness Dystonia Syndrome Caused by ACTB Gene Mutation
Deafness-Dystonia Syndrome (DDS) is a rare and complicated disorder which can be caused by a pathogenic heterozygous mutation c.547C>T, p.(Arg183Trp) in the ACTB gene, typically leading to a combination of hearing impairment and dystonia...
View PDF View FulltextThe Influence of CFTR Modulator Treatment on Chronic Rhinosinusitis in a Patient with Cystic Fibrosis – Case Report
Most children with cystic fibrosis suffer from secondary chronic rhinosinusitis for which current treatment options are limited. Novel treatment for cystic fibrosis targeting the cause of the disease shows big promise in increasing pulmonary function...
View PDF View FulltextCase Report: Secondary Membranous Nephropathy with ANCA-related Focal Necrotizing Glomerulonephritis
Antineutrophil cytoplasmic antibodies (ANCA) are the serological hallmark of some idiopathic systemic vasculitis, Pauci-immune necrotizing and crescentic glomerulonephritis (NCGN) is a frequent component of ANCA-associated vasculitis....
View PDF View FulltextEvaluation Of The Therapeutic Effects Of Cardiac Resynchronization Therapy In Patients With Heart Failure With Reduced Ejection Fraction (Hfref) And Concomitant Hypotension
We report a case of a male patient with dilated cardiomyopathy (DCM) leading to heart failure (HF). Following one month of cardiac resynchronization therapy pacemaker (CRT-P), a reevaluation indicated the persistence of heart failure symptoms accompanied by sustained hypotension (90/70 mmHg), ....
View PDF View FulltextEnhanced External Counterpulsation As A Natural ByPass Remedy Of Heart Surgery
It has been demonstrated that EECP therapy, also known as Natural Bypass, improves nearby new blood arteries without the need for stents or bypass surgery. Therefore, it is unnecessary to remove the blockages since fresh blood may flow naturally around this clogged artery, rendering it unimportant.....
View PDF View FulltextPrompt Treatment Prevents Poor Prognosis Of Soft Contact Lens Associated Purpureocillium Lilacinum Keratitis
To report a case of Purpureocillium lilacinum superficial keratitis treated with topical voriconazole.....
View PDF View FulltextA Comparative Study Of Cognitive Behavioral Therapy And Mindfulness-Based Cognitive Therapy For Weight Reduction And Activity Increase In Obese Individuals With Coronary Artery Disease
Obesity is a metabolic disorder and is often the cause of health problems such as cardiovascular diseases. The purpose of this preliminary study was to compare the efficacy of cognitive behavioral therapy (CBT) with mindfulness-based cognitive therapy (MBCT) on activity and weight in....
View PDF View FulltextSJS/TEN Caused by Meloxicam: A Case Report
We reported a case of SJS/TEN in an elderly patient who took meloxicam tablets at home for the treatment of lumbar disc herniation and searched the literature to study the risk factors of SJS/TEN and the factors affecting the prognosis. The case was reported based ....
View PDF View FulltextUnruptured Ovarian Ectopic Pregnancy In Adolescence Case Report
Ovarian pregnancy is one of the rarest types of ectopic pregnancy. Its preoperative diagnosis remains a challenge because of it presents quite similarly to tubal pregnancy....
View PDF View FulltextGuillain-Barré Syndrome With Nine Positive AntiGlycolipid Antibodies A Case Report
Objective: to investigate the clinical characteristics of nine glycolipid antibody-positive patients. Method: the clinical data of a patient with Guillain-Barré syndrome were retrospectively analyzed. Result: A 69-year-old ....
View PDF View FulltextAspiration Of Capsule Endoscopes: A Case Report And Treatment Experience From Respiratory Physician
Capsule endoscopy (CE) is an effective tool for evaluating the intestinal lumen through video, and its use has become widely accepted in gastrointestinal investigations. However, capsule aspiration into the trachea or bronchial tree ....
View PDF View FulltextAnti-Sperm Antibody Positivity Results A Decrease In Sperm Penetration Rate Both In Vivo And In Vitro: A Systematic Review And Meta-Analysis
Anti-sperm antibodies (ASA) that bind to sperm have been associated with infertility, but most of the available studies have conflicting results.....
View PDF View FulltextDevelopment of a Behavioral Satisfaction Questionnaire for CBT Psychoanalysis
The research reports the development of a behavioral satisfaction questionnaire (BSQ) for the use in cognitive-behavioral therapies (CBTs). It is purposed for semi-structured psychoanalytic interviews, but can also be used for self-report. The design of BSQ seeks to organize a referential scale with ....
View PDF View FulltextAs A Good Prognostic Sign, Autosplenectomy Is Higher In Females In Sickle Cell Diseases
Sickle cell diseases (SCDs) are inborn and destructive processes on vascular endothelium, particularly at the capillaries.....
View PDF View FulltextCan We Avoid A Protective Stoma And Improve Functional Results After Surgery For Rectal Cancer? Reinforced And Delayed Colo-Anal Anastomosis: A New Technique Observational Study About 5 Cases
Colorectal cancer is a common cancer, accounting for nearly 10% of all cancers (Source: Globocan 2020), and ranking first among digestive cancers. More specifically, cancer of the rectum represents between 30% and 40% of colorectal....
View PDF View FulltextPeritoneal Tuberculosis: A Benign Differential Diagnosis Of Ovarian Cancer With Peritoneal Carcinomatosis: A Case Report
Peritoneal tuberculosis is a rare form of tuberculosis which gives a nonspecific clinical picture which can be confused with several digestive pathologies. It can also mimic ovarian cancer at the stage of peritoneal carcinomatosis, hence the interest....
View PDF View FulltextEvaluation Of Major Adverse Cardiac Events After Cardiac Surgery In Gaza
The present study assessed the major adverse cardiac events (MACE) (hospital mortality rate, major stroke and reintervention) after cardiac surgery due to coronary artery bypass grafting or valve surgery or both in the Ministry of health hospitals (MOH) in Gaza Strip at 2022 by either Local or Expert cardiac surgery team. ....
View PDF View FulltextCase of Successful Treatment of Acute Respiratory Distress Syndrome in The Parturient Woman With Systemic Lupus Erythematosus and Cerebral Cyst of The Third Ventricular Complicated By Posterial Reversible Encephalopathy Syndrome
Pregnancy and the postpartum period provoke an exacerbation of systemic lupus erythematosus (SLE), which requires aggressive cytostatic therapy that can cause life-threatening conditions for the fetus and complications for the mother,....
View PDF View FulltextPituitary Metastasis Of Signet-Ring Cell Carcinoma Cell Carcinoma Of The Lung With Diabetes Insipidus As The Initial Presentation:A Case Report
Pituitary gland is a rare site for metastasis of malignant tumors. Pituitary metastases accounted for 0.4% of all intracranial metastases and only 1% of operative pituitary lesions [1,2]. But that number is likely to keep rising as patients with metastatic....
View PDF View FulltextAn Unusual Cause Of Ascites: Cerebrospinal Fluid Pseudocyst
We report a rare case of a cerebrospinal fluid (CSF) perihepatic pseudocyst presenting as symptomatic transudative ascites in a 42-year-old patient with a history of ventriculoperitoneal (VP) shunt insertion for spina bifida associated hydrocephalus. ....
View PDF View FulltextHemoperitoneum Due To Trauma In The Superior Pancreatic Artery
Abdominal trauma, specifically hemoperitoneum due to retroperitoneal injury, represents a challenge for the surgeon who works in the emergency department. Hemoperitoneum due to rupture of a branch of the dorsal superior pancreatic ....
View PDF View FulltextIntroduction of Percutaneous Nephrolithotomy In Hungary In 1984
I received the letter from Professor Mauermayer by return of post from Munich. I had travelled to wherever I had lean the chance to get a glimpse of different workshops whether....
View PDF View FulltextRadiotherapy As A Treatment Of Hairy Cell Leukemia: A Case Report
Hairy cell leukemia is an unusual cancer of the blood. It affects B cells, the cause of this disease is unknown. It affects men more often than women. The average age of diagnosis is 55 years old. It is considered a chronic lymphatic ....
View PDF View FulltextModeling And Sensitivity Analysis Of Environmental Indicators For Land Leveling Using Integrating Artificial Neural Network And Genetic Algorithm (GA-ANN)
Land leveling is one of the most important steps in soil preparation for consequent objectives. Parallel policies need to take both energy and environmental subjects into the account as well as certain financial development and eco-friendly....
View PDF View FulltextFast Object Perception In The Subcortical Pathway
The subcortical visual pathway is generally thought to be involved in dangerous information processing, such as fear processing and defensive behavior. A recent study, published in Human Brain Mapping, shows a new function of the....
View PDF View FulltextAarogyaPath :- National Health Care Supply Chain Management
Aarogyapath, a web-based solution for the healthcare supply chain that provides real-time availability of critical supplies launched. ....
View PDF View FulltextUnerupted Teeth, A New Symptom Of Amyloidosis?
Amyloidosis are rare diseases related to the pathological aggregation and accumulation of misfolded proteins in the extracellular space generating.....
View PDF View FulltextRelationship between Malnutrition and Anemia among In-Patient Children at Rahmah Teaching Hospital, Irbid-Northern Jorda
Anemia and malnutrition are common health problems in developing countries with children being the most vulnerable. They .....
View PDF View FulltextSynthetic Peptide LKEKK as Potential Antipsoriatic Drag
It has been established that the synthetic peptide LKEKK affects the ability of IL-12 to regulate the secretory activity of keratinocytes obtain.....
View PDF View FulltextThe mass of the Milky Way galaxy
On the Basis of tabular values of the gravitational constant. The calculated mass of the nucleus of the milky way galaxy. The numerical value of the .....
View PDF View FulltextAtypical Presentation of Pyloric Stenosis in Babies in Critical Care
Pyloric stenosis usually presents with well defined symptoms and signs. However, these may be absent in neonates in intensive care for.....
View PDF View FulltextRare Primary ThymicТ-Lymphoblastic LymphomaIn Childhood-Сlinical Case From Our Practice
Asstated in the current World Health Organization class ification, T-lymphoblastic leukemia/lymphoma is a neoplasm of lympho- blasts committed to T-cell lineage involving bone marrow (BM), blood, or .....
View PDF View FulltextOne Case of Abnormal Liver Function with Unknown Reason
One case of abnormal liver function with un- known reason was reported in this paper. It was a rare case with rare manifestations.....
View PDF View FulltextCase Report: A52-Year Healthy Woman Developed Severe Microwave Syndrome Shortly After Installation of a 5G Base Station Close to HerApartment
In this case report we present a woman aged 52 years who developed health problems consistent with the microwavesyndrome after installation of a 5G base station facing her apartment at 60 meters’distance.These symptoms consisted of e.g., headache, diz- ziness, concentration difficulties, fatigue, arrhythmia, skin burn- in gandnose bleeding corresponding to th emicrowavesyndrome .....
View PDF View FulltextSoliton Phenomena in the Process of the Functioning of the Heart
The biochemical model explains the intricate mechanisms of psy- chobiological life. He still cannot explain what the transition from inanimate to living matter is all about. Where is the threshold and what is its .....
View PDF View FulltextComparison of Two The ories of Hearing
recognizesit and calculates the value of inertiain the ear byusing theformula: (2πx frequency)2 x amplitudexmassg/ mm/s2. For a threshold tone of 1,000 Hz and 0 dB, the inertia of the middle ear is 0.009859 g/mm/s2. For a tone of 10,000 Hz and 100 dB, the inertia of the middle ear is 98596 g/mm/s2. For each frequency, the value .....
View PDF View FulltextMulticentric and Prospective Trial of Vulvovaginitis Treatment Comparing Propionibacte- rium Extract [Immunovag®] With Metronidazole Plus Clotrimazole [Meclon®]
Vulvo-Vaginal Infections [VVI] strongly interferes with the wom- an’s quality of life. Antibiotic treatments, alone or combined with an antifungal compound, are commonly and successfully used. Nevertheless, .....
View PDF View FulltextMegaloblastic Anemia
Folic acid and cobalamin are B-group vitamins that play an es- sential role in many cellular processes in the body. Deficiency in one or both of these vitamins causes megaloblastic anaemia.This is a disease .....
View PDF View FulltextThe Efficacy of Cisapride in Infants with GERD-Meta-Analysis
Infants often have gastroesophageal reflux disorder (GERD), and Cisapride is prescribed for treatment. This study aimed to assess the effectiveness of Cisapride in treating GERD in newborns, while considering its adverse effects and its removal from the market.....
View PDF View FulltextShoulder Injury Related to Vaccine Administration After Covid-19 Vaccination: A One-Year Observational Single-Center Study
Due to widespread vaccination caused by the global COVID-19 pandemic, a large proportion of the population has experienced shoulder pain after vaccination. Shoulder injury related to vaccine ......
View PDF View FulltextSafety and Efficacy of Microwave Ablation to Treat Pulmonary Nodules with Hydromorphone Versus Morphine
To compare the safety and efficacy of computed tomography-guided percutaneous microwave abla- tion (MWA) in treating pulmonary nodules under conscious anal- go-sedation with hydromorphone versus morphine. . .....
View PDF View FulltextRecurrent Pegfilgrastim-Associated Migratory Large Vessel Vasculitis in a Patient with Breast Cancer with Rare HLA Haplotype: A Case Report
Granulocyte-Colony Stimulating Factor (GCSF) rarely induces severe systemic vasculitis. However, diagnosing vasculitis can be challenging because clinical mani- festations in.....
View PDF View FulltextParadoxes of the Theory of Gravity
Showing the contradictions in the physics calculations using the equations of the classical theory of gravitation. Alternatively, in- vestigate the physical properties of space objects on the basis of the .....
View PDF View FulltextA Pre-Neop lasticLesion: A Case Study
: The aim of this paper istoreporta case of Actinic Dermatosis in an 8-year-old female adult dog with erythematous skin. In the clinicalevaluation,the animalpre sented normal parameters for the .....
View PDF View FulltextModified Elmslie-Trillat Technique for Knee Cap Dislocation: A Retrospective Study with 5 Patients and 1 Year Follow-Up
: Knee capdis location is a commonor thopedic injury that canlead tosignificantpain, instabilit yand kneedys function. Surgicalman- agement of knee cap dislocation involves various techniques in- cluding anteromedialisation and arthroscopic lateral release. The modified Elmslie-Trillat technique combines the set woprocedures .....
View PDF View FulltextThe Chinese the Asia Tallest: How and When?
: Japan was a forerunner in rapid economic development in NE Asia after WWII, followed by South Korea with two decades behind due to Korean War (1950-53). Children in Japan started to increase in height.....
View PDF View FulltextEffect of an Intravenous Administration of Adipose-Tissue-Derived Autologous Stem Cellson the Skin Temperature of Paralyzed Limbs of Stroke Patients
: The hearing theory announced in the first half of the 20th century by Georg von Bekesy requires reviewing and updating. There has been a huge advancement in the sciences ever since, which allows to .....
View PDF View FulltextA New Vision of Hearing
: The hearing theory announced in the first half of the 20th century by Georg von Bekesy requires reviewing and updating. There has been a huge advancement in the sciences ever since, which allows to .....
View PDF View FulltextManaging Dysmenorrhoea and Chronic Pelvic Pain in Adolescence: A Guide for Clinicians
: Chronic pelvic pain and dysmenorrhoea are not so rare in adoles- cence. It is important to assess clinically young girls with these symptoms to exclude gynaecological conditions like endometrio- sis .....
View PDF View FulltextA Role for Nucleotide-Binding Oligomerization Domain (NOD)-Like Receptor Protein 12 (NLRP12) in Paediatric Inflammatory Bowel Disease (IBD): A Case Report and Literature Review
Paediatric inflammatory bowel disease (IBD) is a chronic disease with a multifactorial etiology. The role of nucleotide-binding oligomerization domain .....
View PDF View FulltextNordic Appeal: More Stringent Regulatory Frame work on Microwave Radiation from Wireless Technologies is Needed - Stop Further Rollout of 5G
In recent years, people’s exposure to pulsed radiofrequency (RF) or microwave radiation from wireless technologies has exploded, mainly due to .....
View PDF View FulltextTreatment of Post Pelvic Surgery Lower LimbLymphedema UsingHerbal Medicine
: The reported case was a 40-year-old fe- male who was diagnosed as late uterine cervical cancer.....
View PDF View FulltextSuccessful Rechallenge of Hepaftocellular Carcinoma with Atezolizumab and Bevacizumab Following Disease Progression
Systemic therapies to treat Hepatocellular Carcinoma (HCC), a cancer with traditionally poor prognosis, have greatly advanced in the last five years with the advent of immunotherapies. The immune checkpoint inhibitor atezolizumab and anti-angiogen- ic agent bevacizumab combination therapy is now ....
View PDF View FulltextFor Nutritionally Beautiful YOU...!
Antioxidant present in fruits and veggies may help you to do so. They help you to keep away from signs of ageing too. Blueberries, grapes and spinach are few. Supplements of omega 3 fatty acids or /and adding salmon, walnut is good to help give your skin a glow....
View PDF View FulltextPositive TESE after Orchidopexy of Bilatera Abdominal Cryptorchidisminan Adult: A Case Report
Undescendedtestisisacongenitalanomalythat is usually discovered in childhood and undergoes orchidopexy. Undiscovered adult patient with this condition usually undergoes orchiectomy due to atrophy of....
View PDF View FulltextUse of the EIS (Electrical Impedance Segmentography System) in Less-Invasive Surfactant Administration (LISA) in New-Borns Suffering from Respiratory Failure
Electrical Impedance Segmentog- raphy System simultaneously detects transthoracic impedance changes, which are directly proportional to the amount of gas vol- ume in the lung, allowing regional and dynamic monitoring of pul- monary ventilation in real time. It is a complementary technique to the most common methods used in the context of respiratory failure in the new-born. We want to demonstrate how a simple, non-invasive, free of radiation bedside monitoring method can provide us extemporaneous feedback about the ventilatory condi- tion of the new-born suffering from respiratory failure and treated with surfactant administration, even before the aid of an X-ray is required. ....
View PDF View FulltextExtraskeletal Mesenchymal Chondrosarcoma of Maxillary Sinus :A Case Report
Extraskeletal Mesenchymal Chondrosarcoma (ESMC) originating in the sinonasal tract has rarely been reported. Reports related to its imaging features are even rarer, which makes preoperative diagnosis ....
View PDF View FulltextVascular Abnormalityin Hemodialysis-Associated Is chemic Priapism: A Case Report
Ischemic priapism is a rare condition with ful- lypenilerigidityandseverepain.Bloodtrappinginthepenisis a crucial pathophysiology for ischemic priapism, but the reason causing the blood trapping varies....
View PDF View FulltextA Novel Role of AIM2 Inflammasome-Mediated Pyroptosis in Radio frequency Ablation of Hepatocellular Carcinoma
Hepatic in flam mation and in flamma some-me- diated mechanisms are involved in the pathogenesis of Hepato- cellular Carcinoma (HCC), and Absent in Melanoma 2 (AIM2) triggers activation of thein flamma some cascade.Untilnow....
View PDF View FulltextSevere Intracr an ial Subdural Hematoma Following Epidural Anaesthesia in Pregnancy:A Case Report
Severe headache is one of the quite common complication after a dural puncture procedure beitdi agnostic (lumbarpuncture) or unintentional....
View PDF View FulltextFunctional Correction of the Musculos keletal Frame work-The Basis of the Therapy of a Self-Regulating System
The history of mankind dates back thousands of years, and only in recenty ears has the rebeenar apidinc rease in the percentage of cases,....
.... View PDF View FulltextOxygen Uptake During Walking in Three Types of Microprocessor-Controlled Prosthetic Knee Joints in a Middle-Aged Male with Bilateral Transfemoral Amputation
Individuals with bilateral transfemoral amputations experience great difficulty in prosthetic ambulation in their community because of high....
View PDF View FulltextA Rare Complication Following SARS-Cov-2 Infection: ST-Elevation Myocardial Infarction and Bilateral Pulmonary Embolism
Sars CoV-2 infection has been associated with a hyper coagulability leading to increasedin cidence of thromboembolism. However, it is exceedingly....
View PDF View FulltextSchool Children’s Height in Beijing
This joint report by a group of noted human biologists in Beijing examines secular growth of school boys and girls, 7 to 17 yearsofage,....
View PDF View FulltextEmpyema Caused by Strept ococcus Constellatus: A Case Report
Streptococcus constellatus is an opportunistic pathogen of Streptococcus angina. It is easily to be ignored by routine clinical laboratory tests for it sprolonged an aerobiccultur e environment....
View PDF View FulltextCervix Epithelioid Trophoblastic Tumor: A Rare Case Report and Review of the Literature
The epi the lioidtrop hoblastic tumour(ETT)is a veryrare type of gestational trophoblast neoplasm (GTN), accounting for 0.5%-2.0% of all GTNs. With the irunusual ability to simulate an invasive epithelioid neoplasm, ETTs frequently pose a diagnostic....
View PDF View FulltextAdenoid Cystic Carcinoma of the Nasal Fossa: A Case Report and Review of the Literature
Adenoid cystic carcinoma of the nasal cavity is a rare malignancy. It is a slowly progressive disease, characterized by local recurrences and distant metastases and requires early and adequate management. We report a case....
View PDF View FulltextPrimary Bronchial Acinic Cell Carcinoma: A Case Report and Review of the Literature
Acute myocardial infarction (AMI) is an uncommonfinding in young patient sunder age 35 and determination....
View PDF View FulltextStudy On Clinical Features and Pathogenetic Factors Associated with Diabetic Foot Gangrene
Objective to explore the differences in clinical features, lesion location, and pat homechanism between different types of diabetic foot gangrene and provide....
View PDF View FulltextTransvaginal Cornual Pregnancy Reduction Reduces the Risk of Bleeding in Cornual Heterotopic Pregnancy with Severe Pelvic Adhesions: Case Reports and Literature Review
The objective of this research is to explore the individualized treatment of Cornual heterotopic pregnancy (CHP).....
View PDF View FulltextMultiple Meningiomas: Case Report and Review of Literature
We present a case of a 63-year old man with multiple meningiomas, with noevidence of neur of ibromatosis2....
View PDF View FulltextLoss of Taste, Smell and Oral Manifestations in COVID-19
COVID 19 mainly affects the respiratory, gastrointestinal and neurological systems but it al soinvolves the oralcavity, olfactory and integumentary systemn....
View PDF View FulltextA Valve Repair after In fective End ocarditis Secondary to Perforation Causedby Streptococcus Gordonii -ACase Report and Literature Review
We report a case of infective end ocardit is inapatient with congenital heartval velesions accompaniedby Strept ococcusgordonii in fection.A61-year-oldmanpre sented with recurrent fever for four months. Immune....
View PDF View FulltextHistomorphological Patterns of Hysterectomy Specimens in A Tertiary Care Hospital: A Two-Year Study
Hysterectomy is the secondmost commongyne cological surgery next to caesarean section.The indications for hysterectomy may vary from one region to another and histomor- phological pattern may also vary....
View PDF View FulltextNovel Pathogenic Variant of Fumarate Hydratase in Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome (HLRCC): A Case Report
Hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC) is a rare genetic disease, which is caused by the mutation of fumarate hydratase (FH) gene and in- herited by autosomal dominance....
View PDF View FulltextAcuteST-Elevation Myocardial Infarction in a32-Year-Old MaleLess than 2Months after a Normal Coronary Computed Tomography Angiography
Acute myocardial infarction (AMI) is an uncommonfinding in young patient sunder age 35 and determination....
View PDF View FulltextA Rare Case of Cortical Blindness Following Cysticercal Encephalitis in a Child
Neuro-cysticercosis, a parasitic infection of the brain caused by T. solium, is the most common central nervous system parasitosis globally. Seizures, headaches, hydrocephalus and varying degrees of loss of ....
View PDF View FulltextEosinophilic Ascites Due to Eosinophilic Gastroenteritis: A Case Report and Review
Eosinophilic gastroenteritis (EGE) is a rare disease characterized by the presence of gastrointestinal symptoms with an abnormal eosinophilic infiltrate of the intestinal wall and exclusion of other causes of secondary....
View PDF View FulltextA Novel Frameshift Mutation in GPT2 Gene Found by Whole Exome Sequencing Causing Mental Retardation and Seizures
Some studies reported GTP2 gene missense mutations are associated with neurodevelopmental delay with spastic paraplegia and microcephaly. Here, we report a new frameshift mutation of this....
View PDF View FulltextA New Missense Mutation of SPTBN2 with Spinocerebellar Ataxia Type5: A Case Repor
Spinocerebellar ataxia type 5 (SCA5), dominant spinocerebellar ataxia caused by mutations in the SPTBN2 gene, SCA5 is clinically described as a slowly progressive cere- bellar ataxia with little involvement of the brainstem or spinocere-bellar tract or brain, occurring mainly in adulthood....
View PDF View FulltextEpithelioid Angiosarcoma of Masticator Space: A Case Report of CT Manifestations and Follow-Up
Epithelioid Angiosarcoma (EA) is a special subtype of angiosarcoma, which is common in skin and connective tissue, and its incidence reaches the peak in men aging over 60 years old. EA occurring in masticator....
View PDF View FulltextHistopathology and Immunohis to chemical Examinations in Adenosqu amous Carcinoma, Cancer of the Stomach - Case Stud
The author spresenta case of gastricad enosqua mouscar cinomain a 62-year-old femalepatient. Amonthearlier, anadenocarcinoma infiltration was diagnosed during gastroscopy in the histopathological examination of specimens from the pyloric ulcer. Intraoperatively,....
View PDF View FulltextGiant Partially Thrombosed Anterior Communicating Artery Aneurysm Presenting with Cognitive Decline and Gait Disturbance
Aneurysms usually present with subarachnoid hemorrhage and signs of i ncreased in tracranial pressure. Patients who surviveafter their first bleeding , have an estimated annual risk of rebleeding which is 1.27%. Wepresenta....
View PDF View FulltextDisparity of Interstitial Glucose for Capillary Glucose in Dialysis Diabetic Patients
The prevalence of chronic kidney disease (CKD) has steadily increased and diabetes is now considered the leading cause of endstage kidney disease (ESRD). Glycemic control in chronic renal patients on dialysi....
View PDF View FulltextAge-Related Composition of BMI and Body Composition Basedon Fujimmon’s Growth Curve
The pubertal peak in body fat percentage was estimated and its relationship with menarche was previously investigated in regard tochanges with age in BMI ....
View PDF View FulltextPreliminary Study on the Application of “5G+AR” Portable Equipment for Emergency in Zhoushan Islands
The geographical environment of Zhoushan Islands makes it difficult for people to get standardized emergency treatment. Based on the current two hot technologies,....
View PDF View FulltextSuccessful Secundigravida in Fulminant Type 1Diabetes Mellitus: A Case Report
Purpose:Top resenta woman with successful secundigravida after being diagnosed fulminant type 1 diabetes mellitus ....
View PDF View FulltextThe Superiority of Amniotic Membrane in the Treatment of Aplasia Cutis Congenita
Aplasia cutis congenital (ACC) is a heterogeneous group of disorders that sharea common feature off ocalskin loss. In most cases, this is limited to the scalp, also involve other parts of the body ....
View PDF View FulltextSevereand Transient Thrombocytopenia Following the Third Dose of COVID-19 Vaccine (mRNA-1273): A Case Report
Autoimmune thrombocytopenia after coronavirus disease 2019 (COVID-19) vaccination rarely occursasadver seeven tsandusu- ally occurs after the first or second dose.We report the case of an 89-year-old woman....
View PDF View FulltextComa Due to Wernicke Encephalopathy During Neoadjuvant Chemotherapy for Breast Cancer
We report the case of a 49 yr., woman who developed a coma during neoadjuvant chemotherapy for breast cancer. Brain MRI was crucial for the diagnosis of Wernicke encephalopathy....
View PDF View FulltextA 16-Year-Old Girl with Hereditary Hemorrhagic Telangiectasia
A 16-year-old girl was admitted to the hospital with severe abdominal pain that could not be relieved. She was initially misdiagnosed as enterocolitis and did not improve after symptomatic treatment,....
View PDF View FulltextDr Charles James deVis, M.R.C.S.,L.S.A. England, Surge on to the Charters Towers Hospital, 1881-1892
Dr.Charles James de Viswasborn in West Bromwich, UK, qualified as a doctor in England, and migrated to Australia where he spentmost of his abbreviated working life in the north Queens land town of Charters Towers
View PDF View FulltextWhy Korean Teens Started Declining in Height Growth in The Midst of Economic Prosperity: Despite Increasing Supply of Animal Protein?
In ten years after the end of WWII, Japan’s economy recovered to the prewar level and achieved fast and steady progress toward the 1990s. People, the young in particular learned to eat animal products and the teens grew in height nearly 10 cm by the early-1990s and plateaued in stature after that. South Korea was two decades behind Japan in....
View PDF View FulltextLong-Term Outcomesin Older Patients with Sepsisin the ICU: ARetrospective Study
This study compared the characteristics of older and younger patients with sepsis and analyzed the risk factors associated with 28-day and 90-day mortality in critically ill patients....
View PDF View FulltextImmunogenic Issues in Diabetes, Implications for Covid-19
This research is written by a person with Type 1 Diabetes diagnosed 44 years ago, treated with insulin 43 years, and with a 50- year career in healthcare....
View PDF View FulltextMRI-Guided Stereotactic Craniotomy to Set the Diagnosis of CNS Cryptococcosis. Case Report and Review of the International Literature
Cryptococcosis - a fungal infection - mainly caused by Cryptococcus Neoformans and Cryptococcus Gattii, may affect human central neural system ....
View PDF View FulltextReport of a Severe Case of Pancytopenia Caused by Chronic Brucellosis in Tongliao City, Inner Mongolia Autonomous Region, China
Brucellosis is a type of zoonotic infectious disease that causes serious harm to public health. Inner Mongolia has become one of the most severely. ....
View PDF View FulltextBig Bell Hospital, 1941-1955 - Papere
The ruins of the Big Bell Hospital slumber today under the intense sun of the remote West Australian outback. Between 1942 and 1955 it served a remarkably ..... ....
View PDF View FulltextFrequency of Autoimmune Diseases Associated with Type 1 Diabetes Mellitus in Children and Adolescents in Albania
Type 1 diabetes mellitus (T1D) is the most common chronic autoimmune metabolic and endocrinological dis- ease of children and adolescents. Children and adolescents with T1D are at increased risk of developing other autoimmune.......
View PDF View FulltextPrimary Hemangiopericytoma in Parietal Bone: Literature Review and Case Report
Hemangiopericytoma (HPC) is a tumor from pericytes surrounding capillary walls. Most HPCs grow slowly, but others display aggressive growth. Treatment for HPC is total resection or resection plus adjuvant radiation. .......
View PDF View FulltextRamsay Hunt Syndrome with Chickenpox: A Case Report in Elder Woman
Ramsay Hunt syndrome (RHS) is an infectious disease characterized by delayed activation of latent herpes zoster virus in the geniculate ganglion and subsequent spread to cranial nerve. Although herpesvirus can also .......
View PDF View FulltextA Case of CR Efficacy of Toripalimab for Stage IV Cutaneous Squamous Cell Carcinoma
Squamous cell carcinoma is a relatively common malignant tumor of the skin. There are individual differences among different tumor patients and possible differences in the combination of drugs in treatment. Therefore,.......
View PDF View FulltextEsophageal Stenosis Due to Coexisting Conditions Dysphagia Aortica and Thoracic Compression Fractures
A 90-year-old woman presented to the emergency room with dyspnea and a sensation of being choked after eating red rice with beans. This was her first such experience. She was capable of vocalization. Physical examination.......
View PDF View FulltextEfficacy and Safety of Bovhyaluronidase Azoximer (Longidaza) in Patient swith Post-COVID-19 Syndrome: Results of the Open-label Prospective Controlled Comparative Multicenter Clinical Trial Dissolve
Post-COVID-19 syndrome is a condition that develops in the patients recovered from COVID-19 resulting into the cumulative effects of dyspnoea and impaired lung function. .......
View PDF View FulltextTranscatheterArterial Embolization of the Common HepaticArtery for Pseudoaneurysm after a Laparoscopic-Assisted Pancreaticoduodenectomy: A Case Report
Common hepatic artery (CHA) pseudoaneurysm is a rare and potentiallylife-threateningcomplication after pancreaticoduo denectomy, andthepossiblecauseisunclear.Wereportacaseofintraperitoneal hemorrhage after pancreaticoduodenectomy who was discharged after embolization under DSA. We consider that this complication may be related to iatrogenic injury.......
View PDF View FulltextSynthesis, Anticancer And Catalytic Activities Of Novel Mono Nuclear Cu2+, Co2+, And Zn2+ Complexes Involving Benzotriazol, Ethane-1, 2- DiamineAnd 4,4’- Diaminocyclohexylmethane Ligands
Inthisstudy, servaleco-friendly novel complexesweresyn the- sized and characterized having the general formula of [CoC46H- Cl N O ](I),[CuCHCl N O ](II),[CuC HCl N O ](III) history. Soriano-García et al. (2007) synthesized 3β-(p-iodobenzoyloxy)-16α, 17α-epoxypregn-4-En-6,20-dioneandusedit in the treatment of and rogen-dependentdiseases[11]. In2020,Hasijaet e.......
View PDF View FulltextFrom Cardiomyopathy to Endocrine Disorders Diagnostics Acromegaly During Routine Echocardiography
The case of a patient treated so far due to arterial hypertension, requiring complex therapy who was referred to the Department of Cardiology due to ACS and suspected hypertrophic cardiomyopathy. In the echocardiography- the left ventricular ejection fraction was normal, enlargedheart......
View PDF View FulltextBronchial Artery Embolization as a Life Saving Procedure An Interesting Case Report
Haemopty sisisafairly commoncond it ionwhichisen countered in an emergency setting. However, the exactcause may not beeasily identifiable. In such scenarios, bronchial artery embolization can beconsidered to stop the bleeding. This canbeper formed after a detailed preprocedure.......
View PDF View FulltextChronic Infection Related To Tunneled Catheter for Hemodialysis with Presence of Macroscopic Microbial Biofilm
Although the recommended vascular access for hemodialysis is the arteriovenous fistula, tunneled central venous catheters (CVC) are commonly used for treatment. In hemodialysis patients, infections are the most common cause of morbidity and are the second most common cause of mortality.......
View PDF View FulltextCOVID-19-Associated Pneumothorax: Case Reports
Spontaneous pneumothorax associated with COVID-19 is rare. We reported four cases and reviewed the literature. Among the reports, 29% and 42% were a/oligosymptomatic or symptomatic butimproving,respectively.Cliniciansmustbeawareofthiscomplication because it can happen when the patient with COVID-19 was a / oligosymptomatic or had improving symptoms........
View PDF View FulltextRelationship between BloodAmmonia and Plasma freeAminoAcids Concentration inAdult-Onset Citrullinemia Type 2:ACase Report
Elevated plasmacitrul line (Cit)concentrationisacharacteristic finding in adult-onset type II citrullinemia (CTLN2). However, the plasma free amino acids (PFAA) profile associated with ammonia detoxification has not been fully analyzed........
View PDF View FulltextMedial Compartment Osteoarthritis with a Large Subchondral Geode of Medial Femoral Condyle Treated with Unicondylar Knee Arthroplasty: A Case Report
Osteoarthritis (OA) with a large subchondral geode of medial femoral condylar is not common. The treatment options of this lesion vary according to the location of the cyst and the severity of osteoarthritis, with less invasive procedures such as calcium phosphate cement injection to.......
View PDF View FulltextStreptococcus Mutans in the Oral Cavity as a Risk Factor for Threatened Miscarriage
we have found that the presence of Streptococcus mutans in the oral cavity of a pregnant woman may be a risk factor for miscarriage. We observed that Streptococcus mutans is significantly more widespread in the oral cavity of women with threatened abortion than in those undergoing a healthy pregnancy. We analyse the oral and vaginal bacterial flora of.......
View PDF View FulltextPost-COVID Pulmonary Mucormycosis-A Case Report
Pulmonary mucormycosis, a relatively rare fungal lung disease, is difficult to diagnose. It is increasingly reported immuno-compromised patients that inhale fungal spores in the air or paranasal sinus, resulting in pulmonary.......
View PDF View FulltextGeneXpert MTB/RIF: A Useful Tool for Rapid and Accurate Diagnosis of Tuberculosis and Rifampicin Resistance
The primary objective of this study was to show the usefulness and importance of GeneXpert MTB/RIF, a rapid test that simultaneously detects Mycobacterium tuberculosis complex (MTBC) and resistance to rifampicin (RIF) in less than 2 hours........
View PDF View FulltextWalking Rehabilitation Using Hybrid Assistive Limb (HAL) and Computer-Controlled Long-Leg Orthosis (C-Brace) for an Individual with Chronic Incomplete Spinal CordIn jury: A Case Report
Many individuals with spinal cord injury (SCI) hope to restore walking function irrespective of their impairment. We present a case with chronic incomplete cervical SCI who could regain community ambulation by.......
View PDF View FulltextTherapeutic Perspective of the Multisensory Interior Garden for the Older People
The conceptualization of the inherent relation- ship between man and nature is called biophilia which refers to the belief that humans are genetically predisposed to be attracted to nature. Science has strengthened the hypothesis contributing to its expansion in various fields such as medicine and psychotherapeu- tic interventions.......
View PDF View FulltextDNA Methylation and Epigenetic Events Underlying Renal Cell Carcinomas
Renal cell carcinoma (RCC) refers to a group of tumors that develop from the epithelium of the kidney tubes, including clear cell RCC, papillary RCC, and chromophobe RCC. Most clear cell renal carcinomas have a large histologic subtype.......
View PDF View FulltextTranscatheter Closure of an Anastomotic Leak after the Bentall Procedure with the Guidance of 3-Dimensional Printing
We describe the use of 3-dimensional (3D) printing technology to guide the occlusion of an anastomotic leak (AL) in the ascending aorta........
View PDF View FulltextRisk Analysis of Secular Trends for a Later Age at MPV of Weight in an Earthquake Disaster Environment
The Great East Japan Earthquake occurred in 2011, bringing unprecedented damage to the Tohoku region ofJapan. Today, after 11 years, the scars from that tremendous damage remain. The health damage to young school children has been particularly great. One may imagine a slowing .......
View PDF View FulltextSuccessful Management of a Broken Stylet Retainedin Tracheobronchial Tree: A Case Report
In Covid-19pandemic, the use of video laryn go scope for tracheal intubation is highly recommended due to the increasing distance between patient’s air way and operator. Anendotra chealtubewith an intubating stylet has been proposed to facilitate tracheal tube insertion, especially .......
View PDF View FulltextHeightisa Measure of Consumption that Incorporates Nutritional Needs: When and What?
Japan suffered heavily from WWII. Per capita food supply was 1,450 and 1,700 kcal/day in 1946 and 1947, respectively. Japan’s economy quickly recovered to the pre-war level in 10 years after the war, 2,200 kcal/day in average food supply in 1955, making steady progress toward .......
View PDF View FulltextThe Role of Genetic Mutations in Genes RUNX1, RUNX1T1, CBFB & MYH11 on Core Binding Factor Acute Myeloid Leukemia
Acute myeloid leukemia (CBF-AML) is one of the causes of hematopoietic tissue (bone marrow) called acute myeloid leukemia. In normal bone marrow, early blood cells called hematopoietic stem cells develop intoe.......
View PDF View FulltextThe Risks of Using 2,4-Dinitrophenol (2,4-DNP) as a Weight Loss Agent: A Literature Review
The prevalence of obesity has steadily increased in response to changes in diet and physical activity patterns over the past 10 years, becoming one of the leading causes of morbidity and mortality worldwide.......
View PDF View FulltextAssociation Between Galectin-3 and Oxidative Stress Parameters with Coronary Artery Disease in Tunisian Population
Galectin-3 (Gal-3), as a mediator of inflammation and fibrosis, has been reported to be a biomarker of severity incoronary artery disease (CAD). The study aimed to assess the rela- tionships between......
View PDF View FulltextEarly Detection of Interstitial Lung Disease in Asymptomatic Patients with 2-[18F] FDG PET/CT
Pulmonary involvement is a common manifestation of Dermatomyositis (DM), the most frequent histologic pattern being Interstitial Lung Disease (ILD) which is a major contributor to morbidity and mortality......
View PDF View FulltextDiagnosis of Cavernous Sinus Hemangioma by [99mtc] Tc- RBC Scintigraphy
Preoperative diagnosis of cavernous hemangiomas (HC) is generally difficult because they are rare lesions that are misdiagnosed as meningiomas on Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), being essential their differential diagnosis prior to biopsy......
View PDF View FulltextA Clinical Study of Astragalus Injection in Preventing and Treating Stroke-Associated Pneumonia
Stroke-associated pneumonia (SAP) is a disease with a high incidence in Intensive Care Unit (ICU), which seriously threatens people’s health. However, there is no effective prevention method for SAP. The purpose of this.......
View PDF View FulltextTEMPI Syndrome: A Rare Plasma Cell Paraneoplastic Syndrome That Mainly Characterized by Telangiectasias, Monoclonal Gammopathy, Elevated Erythropoietin Level and Erythrocytosis
TEMPI syndrome is a rare plasma cell paraneoplastic syndrome that mainly manifests as telangiectasias, monoclonal gammopathy, elevated erythropoietin levels and erythrocytosis, perinephric fluid collection and intrapulmonary.......
View PDF View FulltextThe Effectiveness of The Blockade of The Transverse Abdominal Space In The Early Postoperative Period after Cesarean Section
Recently, active research has been conducted in the schemes of multimodal anesthesia of new methods of regional anesthesia based on myofascial blocks. Such blocks include the blockade of the transverse abdominal......
View PDF View FulltextHeterotopic Pregnancy: Case Report
Heterotopic pregnancy is defined by the presence of an intrauter- inepregnancy and an ectopic pregnancy in any location, mostly in the uterine tubes. It is a rare obstetric pathology......
View PDF View FulltextThe Importance of Framing at the Beginning of an Review Dialogue
Long-term care of patients with chronic conditions in general practice rarely focuses on the treatment process. A specific interaction tool, the Review Dialogue.......
View PDF View FulltextDermatological Health in the COVID-19 Era
COVID-19 and its impactonder matological health was reviewed from the oretical and statistical frame works in the present study. A cross-sectional and retrospective work was documented with a selection of sources indexed to Scopus, considering the period from 2019 to 2022.......
View PDF View FulltextSkull Metastasis from Papillary Thyroid Carcinoma: Case Report and Literature Review
Although papillary thyroid carcinoma is a relatively common form of malignancy, metastatic spread to the skull is exceptional. Here, we report a case of papillary thyroid carcinoma revealed by frontal skull metastasis.......
View PDF View FulltextVonlay; A Paradigm Shiftin Post Endodontic Restoration: A Case Report
Porcelainveneers have long been apopular restorative option that have evolved into a well-accepted treatment that canbef abricated in various ways. Onlays are another common treatment modality used in contempor arydentistrytore store largeareas of decayand to replace old restorations......
View PDF View FulltextDental Implants in Patients with Sickle Cell Disease: A Review of Literature
The study aims to review the current literature on sickle cell disease and dental implant as a treatment modality for the replacement of the missing dentition......
View PDF View FulltextNeoadjuvant Therapy for HER-2 Positive Acantholytic Squamous Cell Carcinoma of the Breast: A Case Report
HER2-positive breast ASCC is exceptionally rare, its clinicopathological characteristics are insufficiently studied, and the implications of neoadjuvant therapy, comprising targeted treatment against HER2......
View PDF View FulltextViral Load and Antibody Responses in an Asymptomatic/Minimally Symptomatic SARSCov2 Positive Cohort in Sri Lanka
Asymptomatic patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are silent carriers of the disease. We aimed to characterize their dynamics of disease occurrence, viral shedding and antibody responses using a cohort of asymptomatic/ minimally symptomatic .....
View PDF View FulltextMcKittrick-Wheelock Syndrome: A Rare Occasionina Young Patient
Mckittrick-Wheelock syndrome is afatal and life threatening diagnosis ifnointerventions taken on time. It is due toalargedistal colonpolyp that secretes body saltsin cluding sodium and pottasium and thus, causing severe .....
View PDF View FulltextA Glucagonoma Accompanied with Chronic Necrolytic Migratory Erythema and Multiple Liver Metastasis: A Case Report
Glucagonomaisa next remelyrarep NETs, usually presenting with glucagonoma syndrome,Necrolytic Migratory Erythema (NME) is mostly the first clinical manifestation of glucagonoma syndrome. Here we describe .....
View PDF View FulltextA Novel Case of CASK-Related Microcephaly with Pontine and Cerebellar Hypoplasia Complicated by Airway Disorders
We report a case of skipped multisegmental spinal tuberculosis with tuberculous pleurisy treated with non-surgical management. We discuss the literature, trying to shine a light on the non-surgical treatment.....
View PDF View FulltextToxic Megacolon: A Conundrum
Toxic megacolon is defined as an acute non-obstructive inflammatory condition with dilatation of the bowel causing septicemia and peritonitis......
View PDF View FulltextThe Association Between Mental Health and Caries: A Preliminary Study of Graduate Students in China
We report a case of skipped multisegmental spinal tuberculosis with tuberculous pleurisy treated with non-surgical management. We discuss the literature, trying to shine a light on the non-surgical treatment.....
View PDF View FulltextRadionuclideTracerTechnology inthe Diagnosis of Thoracoabdominal Fistula and Localization of Fistula Points: APilot Study
This studyaims to explorethe clinical utilityof radionuclide tracer technology in the diagnosis and localization of thoracoabdominal fistulas......
View PDF View FulltextAllogeneic Hematopoietic Stem Cell Transplantation Combined with Disseminated Infection by Trichosporon Asahii：A Case Study and Literature Review
Invasive fungal disease (IFD) is a common postoperative complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), the most common.....
View PDF View FulltextA Case of Severe Skin and Soft Tissue Infection in the Left Upper Limb Caused by Aeromonas Veronii
We report a case of severe infection by Aeromonas veronii in the left upper limb caused by accidentally injuring the left thumb while cutting a fish......
View PDF View FulltextSuccessful Treatment of Acinetobacter Baumannii Infection in Burn Child with Avibactam/ Sulbactam: A Case Report
Infection with multi-drug resistant bacteria is an uprising clinical problem that requires the development of new antimicrobial agents. Sulbactam/avibactam increases sulbactam activity against multi-drug resistant .....
View PDF View FulltextClinical and Evolutionary Features of SARS CoV-2 Infection (COVID-19) in Children
Starting with December 2019 the medical world has faced a new challenge as a consequence of a new type of coronavi-rus2019-nCoV, similar to several familiar strains that determine a comparable .....
View PDF View FulltextCombined Application of Ultrasound-Guided Percutaneous Drainage and Urokinase Lavage:An Economical and Effective Treatment for Muscle Hematomas in Hemophiliacs
We report a case of skipped multisegmental spinal tuberculosis with tuberculous pleurisy treated with non-surgical management. We discuss the literature, trying to shine a light on the non-surgical treatment.....
View PDF View FulltextAn Orocutaneous Fistula in a Puckered ScarTreated with Local Flaps:ACase Report
Aesthetic facial reconstruction requires understanding regional anatomy and tissue movement and the ability to use innovatively the tissue adjacent to the defect to create a reconstruction that preserves the function of the area and the cosmetic facial units .....
View PDF View FulltextDislodgement of Left Main Stent Following Intravascular Imaging: How the Technician Disclosed Distracted Stent and Prevented Potential Serious Complications
A 54-years old patient with chronic ischemic heart disease and type 2 diabetes mellitus presented with multivessel coronary artery disease. Complex left main coronary stenosis was treated successfully with.....
View PDF View FulltextPersistence HFRS Infection Risk Among Migrant Outdoor Labours in Shanghai, China: A Case Report
Hemorrhagic fever with renal syndrome (HFRS), a rodent-borne disease caused by hantaviruses, is clinically characterized by fever, circulatory collapse with hypotension, hemorrhage, and acute kidney injury......
View PDF View FulltextLaparoscopic Versus Open Surgery for the Treatment of Colorectal Cancer: A Single Center Experience
The primary objective of this study was to comapare laparoscopic colorectal cancer surgery vs open colorectal surgery on postoperative morbidity and mortality......
View PDF View FulltextTail-Biting and Tail-Chewing in Weaned Holstein Heifers
The objective of this case report was to present an abnormal socio-nutri-psychological behavior ortail-biting/ chewing in weaned Holstein heifers. Dairy heifers raised under commercial systems are separated from their.....
View PDF View FulltextNon-Surgical Treatment of a Case of Skipped Multisegmental Spinal Tuberculosis with Tuberculous Pleurisy
We report a case of skipped multisegmental spinal tuberculosis with tuberculous pleurisy treated with non-surgical management. We discuss the literature, trying to shine a light on the non-surgical treatment.....
View PDF View FulltextEffects of Statin Use On Length of Hospital Stay and Clinical Outcome in Hospitalized COVID-19 Patients: A Retrospective Cohort Study
The search for effective COVID-19 management strategies continues to evolve. Severity of COVID-19 has been reported to be positively correlated with a....
View PDF View FulltextPost Angiography Skin Necrosis Treated with Gracilis Muscle Flap- A Case Report
The use of the muscle flaps for the management of complex groin wound with exposed vessels provide effective and safe coverage. The choice of flap....
View PDF View FulltextNeuropsychiatric Profiles of Brivaracetam: A Literature Review
Anti-seizure medications (ASMs) can cause cognitive or behavioral adverse drug reactions, which is a significant consideration when selecting an appropriate....
View PDF View FulltextDifferential Effects of Long-TermTai Chi Practice on Brain Networks inYoungAdults:A Resting-State Fmri Study
Tai Chi has been found to modulate the intrinsic brain functions andstructures,which has providedclue storeveal the mechanisms behind the clinical effects. The aim of the current study was to investigate the influence of long-term Tai Chi practice in young adults.....
View PDF View FulltextA Case of Childhood Burkitt’s Lymphoma with Gingival Swelling as The First Symptom
Burkitt's lymphoma (BL) is a highly infiltrative malignant lymphoma caused by germinal B-cell differentiation. There are several oral symptoms of BL....
View PDF View FulltextA Difficult Diagnosis of Intraductal Papillary Neoplasia of the Bile Duct (IPNB): A Case Report and Review of Surveillance, Epidemiology, And End Results
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare biliary tumor characterized by papillary growth in the bile duct, a high risk....
View PDF View FulltextPregnancy Luteoma: A Case Report
Pregnancy luteoma is a non-neoplastic lesion of the ovary related to hormonal effects of pregnancy that is usually discovered incidentally at the....
View PDF View FulltextThe Clinical Characteristics and the Pathogenic Gene Mutations in Two Sporadic Cases with Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is an autosomal-dominant disorder characterized by hamartomas in multiple organ systems. Variants in the....
View PDF View FulltextSevere Bradycardia That Lead to Mobitz Type Two Heart Block in A Pregnant African American Female Who Got Infected with Covid-19
Impact of COVID-19 on certain patient populations have been described extensively in several studies. However, the impact of COVID-19 on pregnant....
View PDF View FulltextA Male Infant with Vomiting
A 22-day-old full-term previously healthy male infant, presented to the emergency department with persistent non-projectile, non-bloody, non-bilious vomiting for 4 days. His parents reported....
View PDF View FulltextRestenosis after PCI with Intensive Lowing Density Lipoprotein Cholesterol Reduction: A Case Report
Intra-stent restenosis is an important cause of angina pectoris, and hyperlipidemia has long been considered as the main factor of coronary stent restenosis.....
View PDF View FulltextTexture Analysis of Quantitative ADC Maps to Differentiate Low from High Grade Glioma
Accurate discrimination between high grade gliomas (HGG) and metastatic brain tumor (MET) using noninvasive imaging is essential for selecting appropriate surgical and radiotherapy treatments and for determining the treatment response.....
View PDF View FulltextWhole Tumor Volume Based Histogram Analysis of ADC for Differentiating between who Grade II and III Glioma
The therapeutic approaches and prognosis for gliomas differ considerably for different tumorgrades, it is hence important to accurately assessgliomagrade for treatmentplanning. Inaddition to the use of conventional meanvalue, several studies havere ported the....
View PDF View FulltextThe Role of Mutations on Genes PLAGL1 & ZEP57 in 6q24-Related Transient Neonatal Diabetes Mellitus Syndrome
6q24 Transient Infant Diabetes Syndrome is a type of diabetes that occurs in infants. This form of diabetes is characterized by high blood sugar levels.....
View PDF View FulltextRenalfailure and Quality of Life Indicatorsin Kidney Transplantation
Health-related quality of life (HRQL) contains many aspects of patients' health suchasphysical, psychological, socialfunctioning and ageneral well-being......
View PDF View FulltextManagment of Long Term Care In Era Covid-19
COVID-19 gives the chance to address long-term care categories that are sometimes disregarded and undervalued, such as nursing and residential homes,.....
View PDF View FulltextThe severe Acute Hemorrhagic Necrotizing Encephalopathy in Infected COVID-19 patient
COVID-19 infection initiates a multi systemic inflammatory syndrome with various organ manifestations. Although respiratory symptoms are the most common presentation for COVID-19, neurological manifestations have still been reported, but with devastating outcomes.....
View PDF View FulltextStreptococcus Intermedius Empyema Following Acute Pulmonary Embolism: Case Report
Pulmonary embolism is and has been an established medical diagnosis. The complications, however, seem to awe physicians and healthcare workers across the globe. The purpose of this report is to bring to awareness.....
View PDF View FulltextFOLFOX Combined with Mithramycin-A Has A Cytotoxic Effect On The Primary Colorectal Cancer Stem Cells
To screen out sensitive chemotherapy regimens for cancer stem cells (CSCs) from colorectal cancer (CRC) patients in northeast Sichuan of China and provide the basis for "re-gional precision" targeted therapy......
View PDF View FulltextA Case of Tendon Saving Stapedotomy with Postoperative Recovery of Acoustic Reflex
Tendon saving stapedotomy is a delicate surgical technique which saves stapedius tendon while removing anterior and posterior crua of stapes. Preserving the incus-stapes tendon alignment during operation might give .....
View PDF View FulltextMulti-Traumatized Patient with a Dehiscent Fistulized Abdomen and a Central Venous Line-Associated Infection Successfully Treated with a New Medical Device II
IWe present the case of a patient involved in a multiple-vehicle accident with massive thoracoabdominal trauma who was admitted to a Social Security specialized trauma center in Mexico City. He went through a very complicated postoperative course, including abdominal burst with evisceration...
View PDF View FulltextThe Role of Bone Mineral Density Assessment in Health-Related Quality of Life in Postmenopausal Han Chinese Women Prior to Clinic Diagnosis of Osteoporosis
Osteoporosis is a systemic skeletal disease and strongly associated with reduced quality of life (QoL). The aimof the study was to explore BMD that......
View PDF View FulltextUnerupted Teeth, A New Symptom of Amyloidosis?
Amyloidosis are rare diseases related to the pathological aggregation and accumulation of misfolded proteins in the extracellular space generating insoluble deposits. This may occur in almost any tissue and organ, leading to severe structural damages and functional impairments.......
View PDF View FulltextCommentary: Defecation Delay in Patients After Lung Tumor Surgery: AProspective Nested Case-Control Study
This is a brief commentary to our article “Defecation delay in patients after lung tumor surgery: a prospective nested case-control study” [1]. The author Chen used to be a resident and rotate in different departments......
View PDF View FulltextAfter Sequential Therapy with First and Third Generation EGFR-Tkis, A Patient Acquired EGFR G719A Mutation and Responded to Afatinib, and Then, Acquired EGFR T790M Mutation When Developed Resistance to Afatinib: A Case Report
NSCLC patients who had sensitive EGFR mutation had great possibility to get benefit from EGFR-TKIs. But this efficacy was relied on related EGFR mutation, if related EGFR mutation changed, resistance would happened.......
View PDF View FulltextSARS-Cov2 and limb Ischemia
Patients with severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) infection mainly present severe pneumonia associated with complication srelated tocytokinestormsyndrome. So, it was associated with thromboti cincidents like a cutelimbischemia and pulmonary embolism.......
View PDF View FulltextA Road from Coronary to Pulmonary: A Rare Imaging Presentation
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Its association with Pulmonary Atresia is considered to be the most severe form, the diagnosis of which plays an important role in determination of the......
View PDF View FulltextPrevalence and Determinants of Distress Among Residents During COVID Crisis
Residents are predisposed to develop distress, burnout, and depression. With COVID-19, new stressful working conditions were imposed. This study aims to assess the impact of COVID-19 on residents’ wellbeing in France.......
View PDF View FulltextUlcerative Colitis with Aseptic Abscesses Controlled by Vedolizumab: A Case Report
Aseptic abscesses (AAs) are neutrophilic infiltrative lesions that often coincide with systemic inflammatory disorders such as inflammatory bowel diseases (IBD). According to recent literature, medical therapies in IBD with AAs include co......
View PDF View FulltextA Metastatic Melanoma Patient with Spontaneous Melanoma Associated Vitiligo Survived for up to 7 Years and 5 Months: A Case Report
Malignant melanomaisa highly malignant tumor caused by abnormal proliferation of melanoma cells in the skin and mucous membranes, with apoorprognos is after metastasis.......
View PDF View FulltextGiant Gallstone, Rare Cause for Conversion to open Cholecystectomy from Laparoscopic
Gallb ladder stones is one of the most common disease of the digestive system. Giantgallb ladder stoneisrare and subject to technical difficulties in laparoscopic cholecystectomy with high rate of conversion to open cholecystectomy.......
View PDF View FulltextQuality of Life, After Bariatric Surgery
Obesity is a disease characterized by the abnormal accumulation of body fat. It is estimated that there are 650 000 000 obese adults. Its incidence has increased in recent years, contributing to the decrease in the average life expectancy......
View PDF View FulltextConservative Treatment of Retained Placentas: A Report of Two Cases
To demonstrate conservative treatments for retained placenta accreta in puerperants who underwent induced labour of dead foetuses in the second trimester......
View PDF View FulltextRadiation Therapy of Thyroid-related Eye Diseases
Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease associated with thyroid-related posterior ocular and perimeter orbital tissue invasive lesions......
View PDF View FulltextManagement of Prolapsed End Transverse Colostomy: A Simple Local Revision
Prolapsed colostomy is a well-known complication, occurring with transverse colostomies more frequently than other types of colostomies. It is usually managed conservatively when it is uncomplicated; however......
View PDF View FulltextHerniation of the Ovary into the Canal of Nuck in a 3 Month Old Female Infant: A Rare Entity Needing Urgent Ultrasonography Evaluation
Indirecting uinalhernia of the canal of Nuck containing the pelvic organs such as ovary is a rare entity among females of pediatric age group which presentsass welling of labiamajora. It iscaused by congenitally failedclo sure of the process usvaginalis in female......
View PDF View FulltextEndovascular Treatment of Common Iliac Artery Aneurysm after open Repair for RupturedAAAwith Commercially Available Devices in Bulgaria - Case Report
True iliac aneurysms development is a major sign of an eurysmdisease progression after open repair for Abdominal Aortic Aneurysm (AAA). We present our experience in en- dovascular repair of true iliac aneurysm after open reconstruction ......
View PDF View FulltextSpontaneous Pneumomedia stinum with Subcutaneous Emphysemaina COVID-19 Patient
A 39-year-old man presented to the emergency room with complaints of fever, shortness of breath and pronounced dry coughfor 1 week. On physical examination, his respiratory rate was 28 breaths/min and his oxygen......
View PDF View FulltextSub-Dural Hematoma and COVID-19 Infection: Re-Bleeding Following Anti-Coagulation
Chronic subdural hematoma generally occurs in elderly patients. Anti-coagulation is also a frequent risk factor for this disease. The objective of thisreport was to present the rare case of a right hemispheric subdural hematoma associated with......
View PDF View FulltextEditorial
Let me starts with short explanation which led me to write these words to encourage all of you who had experienced or are still experiencing the problem and situation I had gone through. One eveningjust talking with ......
View PDF View FulltextBio-Statistics Newer Advances, Scope & Challengesin Bio-Medical Research
Biostatistics also known as biometry which means ‘measurement oflife’ is abranch of applied statistics which deals with collection, compilation, analysis and interpretation of data related to biomedical sciences.......
View PDF View FulltextCross-Sectional Study on Prevalence of Psychological Comorbidity in Patients with Psoriasis
This study investigates the prevalence of psychological comorbidity in patients with moderate to severe psoriasis vulgaris. Furthermore, the relation between the type of disorder and the degree of psoriasis severity has been analysed.......
View PDF View FulltextA Giant Multifocal Squamous Cell Carcinoma Arising in a Patient with Hidradenitis Suppurativa
Few reports describe squamous cell carcinoma arising in hidradenitis suppurativa. Although rare, the combination of SCC and HS is often associated with early metastasis and high mortality rates.......
View PDF View FulltextTreatment of Deep Burn Wounds of the Buttocks and perineum using Vacuum Sealing Drainage Combined with a Homemade Anal Canal
The aim of this study was to investigate the therapeutic effects of vacuum sealing drainage technology combined with homemade anal canal treating the deep burn wounds of the buttocks and perineum. From March ......
View PDF View FulltextPrevelance of Ovarian Cancer and Its Corelation with Age in Pakistan
Group of diseases that is originated from the different parts of ovaries and cause production of abnormal cells that divide uncontrolled themselves in the ovaries is known as ovarian cancer.......
View PDF View FulltextTuberculosis: A Rare Cause of Linear Labial Ulceration
Oral location of tuberculosis is rare. It admits a clinical polymorphism and poses above all a problem of diagnosis. We report a caseoflabialtuberculosisina16-year-old patient with underlying lymph node localization......
View PDF View FulltextManagement of Acid Base Disorders in Pregnant Woman
The interpretation of the acid-base statusis key in medical practice, being its most frequent use in critically ill pregnant patients with any type of hemodynamic alteration such as hemorrhagic shock or septic shock, which happens......
View PDF View FulltextComputerized Misinterpretation of QT Interval in 12-Lead Electrocardiogram and Its Clinical Consequences:ACase of Recurrent Syncope
The diagnosis of long QT syndrome may be delayed due to absenceofelectrocardiogram(ECG)examinationand/orQTinterval misdiagnosis. We present......
View PDF View FulltextExtraperitoneal end Tunnel Colostomy Before the Posterior Sheath of the Abdominal Poster Rectus Muscles: A Novel Surgical Technique to Reduce the Incidence Of Hernia
Parastomal hernia is one of the most common complications after colostomy. Preventive strategies are considerable. For less defect and better mechanical work......
View PDF View FulltextClay-Shoveler’s Fracture Caused by Long-Term Bad Posture and Bad Habits: A Case Report
To discuss the fracture of the spinous process of the lower cervical vertebra and upper thoracic vertebra due to long-term bad posture and bad habits, called Clan-Shoveler's fracture. Methods: To analyze the ......
View PDF View FulltextSevere Respiratory Failure from SARS COV 2, Complicated with Pneumothorax in a Pregnant Woman: A Case Report
The first data for COVID-19 in pregnancy showed mild to moderate forms of the disease while current data speaks of severe forms in these subjects. Here we present a case of a severe form of COVID-19 in a gemelar pregnant woman complicated with pneumomediastin and pneumothorax, during her hospital stay, in a late stage of disease.......
View PDF View FulltextThe Role of Cellular Immunity in the Protective Efficacy of the SARS-Cov-2 Vaccine
Several severe acute respiratory Syndrome Coronavirus 2 (SARSCoV-2) vaccines have been approved for clinical use. However, most studies use the SARS-CoV-2-neutralizing antibody titers induced after immunization......
View PDF View FulltextCardiac Myxoma: A Rare Case Series of 4 Patients and a Literature Review
Cardiac myxomas are the most common primary cardiac tumor. Clinical findings are numerous and range from general manifestations to symptoms related to......
View PDF View FulltextEvaluation of a Simulation Program for Management of Cardiovascular Emergencies in Pregnant Women
Medical education worldwide is undergoing a pedagogical renovation movement; medical simulation is one of the revolutionary educational tools whose aim is to improve the medical knowledge,.....
View PDF View FulltextStructure and development of a clinical decision support system: application in high Digestive Gastroenterology
Clinical decision requires to infer great, diverse and not suitably organized quantity of information and having low time to decide. The therapeutic choice is fundamental to formulate a strategy to avoid complications and to......
View PDF View FulltextRectal Cancer Watch and Wait Approach: A Promising Rectal Salvaging Strategy
Colorectal cancer is the third most common cancer worldwide, with rectal cancer being the 10th fatal cancer. The current recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy......
View PDF View FulltextCOVID-19 Associated Loss of Smell and Taste Treated with Gabapentin
Throughout the COVID-19 Pandemic, the symptoms of loss of smell and taste have been commonly encountered by healthcare professionals, and in fact, have become an important screening tool. By some estimates,......
View PDF View FulltextGiant Cell Tumor of the Middle Phalanx of Ring Finger Treated with Wide Excision and Reconstruction using Non-vascularized Fibular Graft: A Rare Case Report and Review of Literature
Giant cell tumor (GCT) involving the hand, specifically the phalangeal bones, is very rare, accounting for only 2% of cases of the bone. This type......
View PDF View FulltextMetastatic Adrenocortical Carcinoma Presenting as Intracavitary Mass in Right Atrium: A Case Report
Adrenocortical carcinomas grow rapidly and tend to metastasize to liver and lungs and invade kidney, renal vein and Inferior vena cava (IVC). Cardiac metastases of the tumor is rare, less than 20 cases have......
View PDF View FulltextMultistrand Titanium Cable Combined with AO Metacarpal Plate in Treating Acromioclavicular Dislocation
As far as we know, no literature is available regarding multistrand titanium cable (MSTC) combined with AO metacarpal plate in treating acromioclavicular (AC) dislocation. Therefore, the current study aimed to evaluate the clinical results of applying such technology in treating AC dislocation. ......
View PDF View FulltextCongenital Panfollicular Nevus
A 1-month-old girl presented to our dermatology clinic with a few irregular asymptomatic nodules on her scalp which were present at birth and had recently increased in size. An incisional biopsy was taken, and the results were compatible with a newly proposed entity called congenital panfollicular nevus.......
View PDF View FulltextBone Metastasis as Initial Presentation of an Aggressive Adenoid Cystic Carcinoma of Mandible: Case Report
Adenoid cystic carcinoma (ACC) is a slowly growing malignant neoplasm with possible widespread distant metastasis. The diagnosis requires thorough ......
View PDF View FulltextIntra-Abdominal Lymphangioma
Lymphangiomas are rare slowly growing benign tumors derived from lymphatic vessels. They occur in various anatomical locations of body like head,......
View PDF View FulltextCOVID-19 Pneumonia in a Congenital Adrenal Hyperplasia; A Case Report
Congenital Adrenal Hyperplasia (CAH) is managed with longterm corticosteroid and is suggested to higher dose, based on the general sick day principles.......
View PDF View FulltextManagement of Shunt complication in a Paediatric COVID 19 Case in Bangladesh Medical College Hospital
V-P shunt is the most common surgery done in paediatric hydrocephalus. Though the surgery remains as ‘minor’ in the arena of Neurosurgery, its complication......
View PDF View FulltextEmergencies in Parkinsonism
Patients with Parkinsonism may present acutely to the ED with serious and even life-threatening conditions. Although falls are a common presentation in advanced Parkinsonism, early presentations with......
View PDF View FulltextRare Bullous Pemphigoid During PD-1 Inhibitor Therapy: A Case Report
Immunotherapy is an important treatment modality in cancer, but it can also cause adverse reactions, with skin toxicity being the most common. The increasing number of immune checkpoint inhibitors being used in the clinic will inevitably cause an increase in the rate of adverse skin......
View PDF View FulltextUncommon Site for Deep Vein Thrombosis in a Kidney Transplant Recipient After Switching Tacrolimus to Sirolimus: A Case Report
We report a 67-year-old male patient who underwent a living related kidney transplantation from his daughter. He developed New-onset Diabetes after Transplantation (NODAT). Sirolimus was introduced and Tacrolimus was stopped to avoid recurrence of......
View PDF View FulltextNF1 Mutated Metastatic Melanoma and Response to Immune Checkpoint Inhibitor Therapy: A Retrospective Analysis
Based on molecular profiling, malignant melanoma is classified in four different groups. NF1-mutated tumors are a small subgroup occurring with a frequency of 13% of all malignant melanomasd recurrent irritation of the bladder. Because of its. ......
View PDF View FulltextYoung Women with Relapse of Acute Lymphoblastic Leukemia Mimicking the Myomatous Uterus
Case presenation of a rare clinical manifestation of a relapse of acute lymphoblastic leukemia in a young woman manifested by growing uterus mimicking a myomatous uterus.......
View PDF View FulltextFour Unique Laboratory Characteristics Applied to Assess the Severity of COVID-19
The sudden outbreaking of COVID-19 worldwide has brought into sharp increased burden of economic and treatment. How to simply, quickly and accurately assess the severity of patients with COVID-19 in the early stage after hospital admission is essential for healthcare systems. ......
View PDF View FulltextCystitis Glandularis: A Case Report of a Rare Benign Bladder Tumor
Pseudotumor or florid cystitis glandularis is the bladder urothelial of the which mainly affects humans [1,2,3]. It is facilitated by chronic and recurrent irritation of the bladder. Because of its. ......
View PDF View FulltextOral Minocycline Challenge as a Potential First-Line Therapy for Myalgic Encephalomyelitis and Long Covid-19 Syndrome
Chronic fatigue syndrome characterized by severe disabling fatigue, prolonged post-exertional malaise, and unrefreshing sleep markedly reduces the activities of daily living and impairs the quality of life. ......
View PDF View FulltextPersonnel Policy and Practice: Sustainable Management of Pharmacy, Pharmacists and Pharmaceuticals and How to Bridge the Gap in Human Resources for Health
Worldwide there are different systems for providing pharmacy services. Most countries have some element of state assistance, either for all patients or selected groups such as children, and some private provisions.......
View PDF View FulltextGenetic Polymorphic Impact of Metabolizing Enzyme (CYP3A4 and UGT1A4 genes) on Anastrazole Response in Iraqi Breast Cancer Women
Anastrazole is an aromatase inhibitor used widely in therapy of breast cancer and has been metabolized by CYP3A4 and UGT1A4 in liver. Breast cancer is the most common cancer type in worldwide and the second causes of death after lung cancer and the......
View PDF View FulltextConcomitant Diseases in a Complex Case of Peritonitis after Stapled Trans Anal Rectal Resection (Starr) in Obstructed Defecation Syndrome (Ods). Role of a Diagnostic and Therapeutic Multidisciplinary Approach
Approximately 0.06-2.3% of the population presents a Jejunal and Ileal Diverticular (JID) disease, of whom approximately 10% develop life-threatening complications such as inflammation, perforation, bleeding......
View PDF View FulltextMucoepidermoid Carcinoma of Parotid Gland: 2 Cases and Literature Review
Mucoepidermoid Carcinoma (MEC) of the salivary gland accounted for 5% of all salivary gland tumors and 20% of all malignant salivary gland tumors [1]. About 50% of salivary gland Mucoepidermoid carcinoma......
View PDF View FulltextA Case of Giant Intrapericardial Teratoma of the Heart in an Infant with a Favorable Outcome
Primary cardiac tumors in newborns and young children are rare, but they affect significantly their health and can be the cause of sudden death. These tumors compromise the integrity and function of adjacent c......
View PDF View FulltextSchwannoma With Extensive Vascular Hyperplasia in the Breast Mimicking Angiosarcoma
Schwannoma with extensive vascular hyperplasia in the breast is extremely rare. It is typically benign and slow growing. Here, we describe a case of 54-year-old woman underwent complete resection of a tumor measuring 2.5×2.0 cm in the breast. The tumor was composed with......
View PDF View FulltextDiffuse Cystic Airspaces in Bilateral Lungs Caused by Anlotinib
A 31-year-old woman, who was diagnosed of stage IVB pulmonary adenocarcinoma in July, 2018, accepted first-line treatment of afatinib and second-line treatment of platinum-based doublet chemotherapy.......
View PDF View FulltextSolitary Gastric Metastasis of Breast Invasive Lobular Carcinoma
A 52-year-old female patient with solitary gastric metastasis from breast invasive lobular cancer without any other organ involvement is presented in this study......
View PDF View FulltextMandibular AV Malformation: Life-Threatening Bleeding from the Mouth Managed by Endovascular Intervention Complicated by Acute Ischemic Stroke on Table. Case Report
Arteriovenous malformations (AVM) of mandibula are rare abnormal congenital vascular condition that can result in serious complications. Although, various treatment options have been advocated in the literature,......
View PDF View FulltextLaparoscopic Resection of Large Endo-Cervical Polyp Through Posterior Colpotomy as an Alternative Access to Vagina in Virgin Patients
Endometrial polyps have been involved in about 50% of patients with abnormal uterine bleeding and 35% of infertile patients. Management of pedunculated end ocervical myoma or polyp normally requires intervention ......
View PDF View FulltextA Typical Lateral Medullary Syndrome
Lateral medullary syndrome (LMS) is a type of ischemic stroke which occurs due to disruption of the blood flow in vertebral artery, or posterior inferior......
View PDF View FulltextRepeated Hemoptysis With Progressive Bronchiectasis: A Case Report of Lady Windermere Syndrome
Bronchiectasis is a type of incurable structural lung disease with clinical manifestations of chronic cough, expectoration or recurrent hemoptysis, which is often given anti-infection and symptomatic treatment. In this study, a patient suffering from bronchiectasis with repeated hemoptysis caused......
View PDF View FulltextPapillomavirus Vaccines Among University Students In Angola
Cervical cancer is the first most common cancer among women in Angola and accounts for 37.6% of cancers among women in Angola. The human papillomavirus (HPV) is a causative agent of the disease.,......
View PDF View FulltextFloating Thrombi in The Right Ventricular Outflow Tract
A 51-year-old woman was admitted to the hospital for an intermittent syncope. No abnormal findings on physical examination. Laboratory results showed B-type brain natriuretic peptide......
View PDF View FulltextImplementing SPADE Protocol (Save Patient from Pain, Agitation and Delirium, Execution Protocol) to Decrease the Incidence of ICU Delirium
This is a proposal for a multidimensional, multidisciplinary protocol pathway model that was dubbed SPADE. Due to pain, agitation, delirium magnitude (PAD) and its effect in intensive care on mechanically ventilated patients,......
View PDF View FulltextStatin as A Cause Immune-Mediated Necrotizing Myopathy: Case Report and Narrative
Statin-induced immune-mediated necrotizing myopathy (IMNM) is an exceedingly rare complication of statin use, which should be suspected in the patient with elevated CPK levels, symmetric proximal muscle weakness and persistence of symptoms despite discontinuation of statin therapy.......
View PDF View FulltextEuglycemic Ketoacidosis and an Absence Seizure in A Type 2 Diabetic On SGLT2 Inhibitors: Case Report and Review of the Literature
In recent years, many new antidiabetic drugs have been developed. One class of these new antidiabetic drugs are sodium-glucose cotransporter 2 inhibitors (SGLT2i). SGLT2i are associated with an increased ......
View PDF View FulltextAnkle Malignant Peripheral Nerve Sheath Tumor in A Neurofibromatosis I Patient: A Case Report and Review the Literature
Malignant Peripheral Nerve Sheath Tumors (MPNST) are rare and aggressive sarcomata’s tumors with an overall incidence of 0.001% [1] derived from Schwann cells or pluripotent cells of the neural crest [2-8]. MPNSTs are typically seen in patients aged 20-50 years,......
View PDF View FulltextA Case of Mycobacterium Abscessus in an Immunocompetent Patient
A 71-year-old lady from the USA, presented with a four-week history of cough and dyspnoea with a cavitatory lesion on her chest x-ray.......
View PDF View FulltextBody Mass Index and Postoperative Outcomes of Patients with Laparoscopic Adrenalectomy. A Single Center Experience
Laparoscopic adrenalectomy has become the standard of care for resection of adrenal masses with extremely low morbidity and mortality. This study investigates the difference in outcomes in patients who underwent laparoscopic adrenalectomy, comparing obese with non-obese patients.......
View PDF View FulltextTherapeutic Challenges in Post-Transplant Lymphopro lif erative Disorder of the Esophagus with Central Nerve System Involvement Complicated by an Esophagotracheal Fistula: A Case Report
Post-transplant lymphoproliferative disorder (PTLD) is a known complication following solid organ or hematopoietic stem cell transplantation. It’s a heterogeneous group of lymphoid and/or plasmocytic proliferations as a result of immunosuppression and is frequently......
View PDF View FulltextClinical Symptoms are Better Than CT Images for Treatment Evaluation and Hospital Discharge in Patients with Coronavirus Disease 2019 (COVID-19)
To determine whether changes in CT are better than clinical symptoms for treatment evaluation, and whether CT is necessary to determine the discharge of patient undergoing COVID-19 treatment.......
View PDF View FulltextJaneway Lesions as The Primary Sign of an Infected Radial Artery Aneurysm After Cannulation
A 52-year-old man with subarachnoid hemorrhage (Fisher 2, World Federation of Neurosurgical Societies Grading Scale 1) underwent endovascular coiling and was admitted to the intensive care unit for standard......
View PDF View FulltextEffect of Preoperative Chemotherapy and Postoperative Adjuvant Chemotherapy for Gastric Cancer with Positive Peritoneal Lavage Cytology (CY1): A Retrospective Study
Peritoneal metastasis is one of the most common forms of metastases for gastric cancer [1]. The 15th edition of the Japanese Classification of Gastric cancer defines patients with positive peritoneal lavage cytology ......
View PDF View FulltextPrevalence and Predictors of Self-Medication in the Younger Elderly of Ahvaz Based on Protection Motivation Theory
The use of medicines is one of the main parts of the treatment of diseases. However, self-medication can be followed several complications. The aim of this study was determine the prevalence and factors influencing self-medication based on protection motivation theory (PMT)......
View PDF View FulltextMultiple-Scale Computational Studies of Redox-Controlled Supramolecular Co-Assembly Nanoplat form: Toward Immunochemotherapy-Driven Antitumor Augment
Programmed cell death protein 1 (PD1)/programmed death ligand 1 (PD-L1) blockades provide an effective and safe therapeutic option in the field of refractory cancer therapy. However, not more than 30% response rate of most cancers seriously impedes their therapeutic efficacy. Previous investigations..........
View PDF View FulltextCytokine Storm Syndrome in COVID-19 Patients: Characteristics and Diagnosis
Cytokine storm syndrome (CSS) is a critical condition induced by a cascade of cytokine activation, characterized by overwhelming systemic inflammation, hyperferritinaemia, haemodynamic instability and multiple organ failure..........
View PDF View FulltextImpact of Anesthetics on the ST Segment Among Patients with Brugada Syndrome: Case Series
Brugada syndrome is a canalopathy causing rhythmic sudden death. The use of many drugs such as anesthetics but also many analgesics are contraindicated or not recommended in this pathology. The literature shows a low-level evidence while clinical experience may bring additional knowledge..........
View PDF View FulltextCase of Anthrax Abdominal Form in Kazakhstan
Anthrax is a dangerous zoonotic infection that is transmitted from farm animals to humans, when cutting, butchering infected animals, contact with meat and other animal products. Infection occurs by contact, alimentary, aerogenic pathways, while developing corresponding clinical forms - skin /ulcerative, abdominal / intestinal, pulmonary /pneumonic.........
View PDF View FulltextWen Dan Tang: A Potential Jing Fang Decoction for Headache Disorders
Chinese herbal medicine is considered relatively safe, inexpensive, and easily accessible. Furthermore, it is becoming increasingly popular in the western countries..........
View PDF View FulltextDeprescribing of Benzodiazepines in the Elderly Using A 3Es Model: A Patient Centered Approach
Benzodiazepines use in the elderly are associated with morbidity including increased falls, fractures, and mortality. The common reason for re-prescribing benzodiazepine by physicians is dependency. Our project........
View PDF View FulltextHepatic Artery Aneurysm Masquerading as Abdominal Pain in a Child: A Rare Case Report
Hepatic artery aneurysm is a rare clinical entity amongst children accounting for 20 % of all the splanchnic artery aneurysms, and if neglected could lead to catastrophic events..........
View PDF View FulltextAssociation between Body Mass Index and Severity According of Classification of Thyroid Cancer
Obesity is associated with aggressive pathological features and poor clinical out comes in breast and prostate cancers. However, the associations between excess weight and prognostic.........
View PDF View FulltextCardiac Transplantation in Patients with Muscular Dystrophy: A Case Report and Review of Literature
We report a case of slowly progressive Becker’s musculardy strophyina 52-year-oldman who required cardiactrans plantation for intractable congestive heart failure. A referral was madeconcerning prognosis of his.........
View PDF View FulltextA Case of Methotrexate-Associated Lymphoproliferative Disorder After Resection of an Accidentally Detected Enlarged Thyroid Tumor
We herein present a case of methotrexateasso-ciated lymphoproliferative disorder (MTX-LPD) with a diagnosisof an 8-mm thyroid tumor of class III cytology that grew three times larger during 2 years 8 months before resection..........
View PDF View FulltextRefractory Vasospasm andArterial Ischemic Stroke in Meningoencephalitis: Novel Intrathecal Nitroprusside Treatment
Acutestroke in bacterial mening it is in children contributes to high morbidity and mortality. The in cidence of strokeinped iatricmening it is isvaried, with reports between 8-42%, and as sociated mortality as high as 25%. The majority of these are arterial ischemic strokes(80-93%). Cerebralarterial vasospasm has been proposed. We present the first case of intrathecal nitroprusside used to treat refractoryvasospasminachildwithbacterialmeningoencephalitis complicated by acute ischemic stroke. .........
View PDF View FulltextHigh LOXL1-AS1 Lncrna Expression is a Prognostic Biomarker For Poor Prognosis in Cholangiocarcinoma
Cholangiocarcinoma (CHOL) is the most common malignant tumor of hepatobiliary system. The present study investigated the clinical significance and biological functions of LOXL1-AS1 in CHOL. The poor survival in CHOL has a probable prognostic molecular marker known as the LOXL1-AS1, and LOXL1-AS1 may be an important regulator of immune cell infiltration.........
View PDF View FulltextPublications Trends in Major Anesthesiology Journals: A 20-Year Analysis of Five Top-Ranked Journals in The Field
With the intention to quantify the importance of a medical journal, the impact factor (IF) was introduced. It has become a de facto fictive rating instrument of the importance of medical journals. Also, it is often used to asses the value of the individual publications within the specific journal. The aim of thepresent study was to analyze publication trends over 20 years in five high-ranked anesthesiology journals.........
View PDF View FulltextCardiopulmonary By pass Graftina PostCOVI-19 Thalassemic Patient
Thalassemia is of the most frequent haemoglobinopathy that includes a heterogeneous group of inherited autosomal recessive pathologies caused by defective synthesis of globin subunit that comprise haemoglobin production.........
View PDF View FulltextPrevalence and Predictors of Self-Medication in the Younger Elderly of Ahvaz based on Protection Motivation Theory
The use of medicines is one of the main parts of the treatment of diseases. However, self-medication can be fol- lowed several complications. The aim of this study was determine the prevalence and factors influencing selfmedication based on protection motivation theory (PMT). ........
View PDF View FulltextRapid Diagnosis of Acute Respiratory Infections by Multiplex Endpoint PCR Technology
The multiplex endpoint PCR technology offersa number of potential advantages, results are available in a matter of hours rather than days, the extreme sensibility facilitates de- tection of even minutes the amounts of pathogen DNA in clinical samples and the test is not significantly affected by prior adminis-tration of antibiotics........
View PDF View FulltextMayer- Rokitansky- Kuster- Hauser Syndrome (MRKH SYNDROME)- An Unusual Case of Primary Amenorrhoea
The onset of mestruation is a significant milestone of sexual maturation in a girl child. Although there are numerous causes of primary amenorrhoea, Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, also known........
View PDF View FulltextCancer Cells-Their Origin
The formation of cells in the body, like the irmutation, isaprocess associated with a violation of the composition and structure of a substance (cells) formed under the influence of an external field surrounding it.........
View PDF View FulltextDelirium Care Pathway Model Design: STOP DELIRIUM
We present a delirium care pathway model that we have dubbed STOPDELIRIUM. Due to delirium's magnitude and effect in elderly hospitalized patients, were commend hospital smusthave a delirium care pathway for early identification, prevention, and delirium management.........
View PDF View FulltextA Case of a Pair of Siblings with Moyamoya Disease
A pair of siblings with Moyamoya disease (MMD) were admitted to our department and treated with superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis and encephalo-myo- synangiosis (EMS).........
View PDF View FulltextCatha Edulis Forskand Its Adverse Effects On Health: Currentand On going Factuality
The leaves of khat tree have an aromatic odor and an astringent and slightly sweet taste. It has been widely chewed for its stimulant action by the population in these regions for many years.Its young buds and tender leaves contain amphetamine-like psy- cho active substances, which produce euphoria and stimulation. Khat is an evergreen shrub,........
View PDF View FulltextA Case of Delayed-Onset Paraplegia at 7 Days After Thoracic Endovascular Aortic Repair
Paraplegia after thoracic endovascular aortic repair (TEVAR) is a common complication, but it is rare for it to occur at 1 week after TEVAR. We describe a patient with delayed-onset paraplegia that occurred 7 days after TEVAR.........
View PDF View FulltextRelationship Between LDH and Mg in Monitoring of Hematologic and Non-Hematologic Malignant Diseases
of this study was to evaluate the correlation between these rumlevels of lactated ehydrogenase (LDH) andma gnesium (Mg) in patients with diagnosed malignant diseases........
View PDF View FulltextFiberoptic Bronchoscopic Treatment of Gastric Aspiration in a Patient with Chest Stomach Ectopia a Case Report
Patients whore ceivedes ophageal resection and gastro-esophageal rebuild before was likely to occur stomach-ectopia to chest when years later. Patients who occurred gastric aspiration during anesthesia have very high risks proceeding to severe aspiration pneumoniaorMendelson’s.......
View PDF View FulltextFatal Anaphylactic Shock from Wasp Sting Despite Desensitisation - A Case Report
Anaphylaxis from Hymenoptera despite conventional venom immunotherapy is rare. We present a case in a previously healthy male with suspected cutaneous mastocytosis, who developed a fatal anaphylaxis due to cerebral hypoperfusion after wasp sting. The report is a reminder that up to 20% of patients allergic to Hymenoptera venom are not protected by conventional venom immunotherapy........
View PDF View FulltextA Protruded Leision with Hemorrhage of Unexpected Histological Findings
An 83-year-old man complained of repeated hematochezia for 3 months.No other medical history was reported except for the percutaneous needle aspiration of left renal cyst 10 years ago. Colonoscopy revealed.......
View PDF View FulltextNon-Structural 5AResistance-Associated Substitutions and Interleukin28B in HCV Genotype 3b Decompensated Cirrhosis Patients with Sofosbuvir Plus Velpatasvir
Hepatitis C Virus (HCV) Genotype (GT) infection is still regarded as one of the more “difficult-totreat”GTs in the era of IFN-free treatments. The viral factors involved in this unfavorable outcome have yet to be clarified.......
View PDF View FulltextGeneralized Eruptive Keratoacanthomas Involving the Auricles and External Auditory Canal:ACase Report and Literature Review
The aim of this study was to report a case of Generalized Eruptive Keratoacan thomas (GEKA) involving theauricl es and external auditory canal and to review the relevant literature.,.......
View PDF View FulltextA Rare Association of a Ruptured Middle Colic Artery Giant Aneurysm and A Celiac Artery Dissection -ACase Report and Literature Review
The occurrence of rupture is the worst among the circumstances of the discovery of a Superior Mesenteric Artery (SMA) branch aneurysm. Despite it remains a rare event, many cases have been reported in the literature. The occurrence correlation of a pancreatico-duodenal aneurysm with isolated celiac artery injury has been proven. However,.......
View PDF View FulltextShort Course Oral Digoxin Treatment inAcute Decompensated Heart Failure: ACase Control Study
Despite many critical voices regarding its efficacy and safety, digoxin may still have a role in the management of heart failure. The objective of this study was to evaluate the efficacy and safety of a short course digoxin therapy started in theemergency department based on clinical outcome after 30 days post hospital discharge........
View PDF View FulltextAcquired SAMD5-RET Fusion-Mediated Resistance to Gefitinib in Metastatic Non-Small Cell Lung Cancer Harboring EGFR-Activating Mutation: A Case Report
Patients with disease progression on first-generation tyrosinekinase in hibitors (TKIs) usually have a poor prognosis.Theme chanisms of acquired resistance to epidermal growth factor receptor (EGFR) TKIs have beenw idely reported; however, reports of acquired rearrangement-during-transfection (RET) fu- sion are rare........
View PDF View FulltextMandibulofacial Dysostosis Guion-Almeida Type: A Syndrome to Recognize in Prenatal
Mandibulofacial dysostosis with microcephaly, Guion-Almeida type (MFDGA) is a rare multiple congenital anomalies syndrome characterized by malar and mandibular hypoplasia, microcephaly, ear malformations with associated conductive hearing loss, esophageal atresia, cleft palate.......
View PDF View FulltextSubclinical Thyroiditis Related to COVID-19: A Case Report and Literature Review
COVID-19 can cause different clinical manifestation by affecting different organs in the body. Involvement of thyroid gland is very rare in COVID-19 infection than any other systems of the body. We described a 41-year-old.......
View PDF View FulltextOver 5 Years of Complete Antiandrogen Withdrawal Response in a Patient with Prostate Cancer: A Case Report
Progressive prostate cancer is primarily treated with androgen-deprivation therapy. The antiandrogen withdrawal (AAW) response (AAWR) is defined as subjective and/or objective improvement following antiandrogen cessation in patients with elevated prostate-specific.......
View PDF View FulltextBilateral Colonic Inguinal Hernia in a Preterm Infant
We presented a case of preterm infant with bilateral colonic inguinal hernia, which was diagnosed radiologically by the initial plain radiograph and subsequent lower gastrointestinal (LGI) study by contrast enema........
View PDF View FulltextTamoxifen May Have a Negative Effect on Bone Mineral Density in Fanconi Syndrome-Related Osteomalacia
A 61-year-old Japanese woman was admitted to our hospital for further examination of generalized bone pain. At age 46 years, the patient was diagnosed with Fanconi syndrome associated with benign monoclonal gammopathy of undetermined significance. At age 56 years, alkaline phosphatase.......
View PDF View FulltextPelvic Solitary Fibrous Tumor
Solitary fibrous tumor is an extremely rare mesenchymal neoplasia divided into pleural and extrapleural form, the latter being considered uncommon........
View PDF View FulltextPlea for an Air-Microbubbles and Air-Blood Interface Free Hemodialysis
Air microbubbles are common in the haemodialysis venous return line, especially in the very first minutes of HD session and with high blood flows. They might be damaging for the lungs microcirculation and stimulate the inflammation system. The origin of air microbubbles is discussed here and practical solutions are proposed to minimize them........
View PDF View FulltextA Case of Retroperitoneal Ectopic Pregnancy and Literature Review
Ectopic pregnancy is a rare female emergency that can have a serious impact on the patient and even threaten life. Retroperitoneal ectopic pregnancy as more rare ectopic pregnancy, its diagnosis and treatment are much .......
View PDF View FulltextThe Use of Essential Oils - Alpha and Β-Pinene in the Treatment of Covid-19
Prophylaxis is not only about wearing masks and vaccines, because no vaccine can guarantee 100% immunity to infection. The best vaccines, based on statistical data from previous years, guarantee approximately 55% certainty of not being infected with a bacterial, viral or fungal infection. Prophylaxis should include a broadly developed psychological .......
View PDF View FulltextBody Packer Syndrome in Sri Lanka
Body packing represents the concealment of illegal substances in a person's body with the aim of smuggling. Body packers either swallow drug-filled packets or introduce drug-filled packets into their bodies through rectum or vagina. In the world, the three main smuggled drugs are cocaine.......
View PDF View FulltextChest Imaging of COVID-19 Pneumonia
A 52-year-old female presented to the emergency department (ED) with fatigue, shortness of breath and cough eight days after being diagnosed with COVID-19. She appeared ill but not toxic, and uncomfortable but not in extremis. Her chest x-ray revealed patchy opacities in bilateral lung bases.......
View PDF View FulltextThe Lethal Effect of COVID-19 on Pregnancy Associated with Neuroendocrine Neoplasm (NEN)
From December 2019, starting from Whuan, COVID-19 pandemic was threatening the entire world population with a major lethal potential. This new infection, with SARS-CoV-2, induces and maintains in human body a significant disturbance in the homeostasis of immune reactions .......
View PDF View FulltextPersistent Hyperglycemia in Brain Tumor Patients Treated with Dexamethasone Peri-Operatively and Post-Operatively
Corticosteroid are commonly used for the management of vasogenic edema and increased intracranial pressure in patients with brain tumors. The purpose of this study was to investigate postoperative and persistent hyperglycemia in patients with brain tumors treated with corticosteroid........
View PDF View FulltextAdult T Cell Lymphoma/Leukaemia with Renal Infiltration: A Case Report from Sri Lanka
Adult T Cell Leukaemia/Lymphoma (ATLL) is a rare T cell lymphoproliferative disease associated with Human T Cell Lymphotropic Virus-1 (HTLV1) endemic in some parts of the world and therefore has a distinct demographic distribution. There are no cases of ATLL.......
View PDF View FulltextMetastasis to Brain and Lung in Carcinosarcoma of the Parotid Gland - A Case Report and Review of Literatures
Carcinosarcoma of the parotid gland is a rare and aggressive malignant mixed tumor in which carcinomatous and sarcomatous elements coexist and metastasize together. The tumor may occur in patients with previous or coexisting pleomorphic adenoma or may arise de novo of the .......
View PDF View FulltextAcute Chlorine Gas Poisoning and Ecg Changes
Chlorine is a yellow-green gas at room temperature. It is an extremely reactive element and a strong oxidizing agent. It has intermediate water solubility and it can cause acute damage to upper and .......
View PDF View FulltextA New Panel of DNA Methylation Biomarkers for Screening Colorectal Cancer and Precancerous Lesions in a Chinese Population
The identification of tumor-specific DNA methylation patterns in epithelial colorectal cells in feces has emerged as a novel and noninvasive screening method for colorectal cancer (CRC) and precancerous lesions. Our study investigates a new panel of DNA methylation biomarkers with high sensitivity and specificity for the early screening of CRC and advanced adenomas in a Chinese population .......
View PDF View FulltextSymphysis Pubis Septic Arthritis
Septic arthritis of symphysis pubis is a rare disease, also known as osteomyelitis of pubic symphysis. It represents less than one percent of all the cases of osteomyelitis. The symptoms are deceiving and can mimic many conditions. This condition usually involves young athletes and women who .......
View PDF View FulltextMedical Schemes and COVID-19 Related Mortality - South Africa: An Explorative Studyt
The COVID-19 epidemic has adversely affected health systems globally, with some on the verge of collapse, as countries experienced the second wave of the pandemic. Millions of people have died from the pandemic, particularly the elderly .......
View PDF View FulltextFatal Attraction: A Case of Multiple Magnet Ingestion in an Infant
Foreign body ingestion is common amongst young children, and they tend to pass spontaneously in most. Multiple magnet ingestion, though not very common, requires early intervention to avoid serious complications........
View PDF View FulltextCongenital True Leukonychia Totalis Case Report, Beyond The Skint
Congenital true leukonychia is an infrequent disorder characterized by a white coloration of the nail since birth without organ or syndromic abnormalities. We present the case of a 16 years old boy with isolated white nail coloration with psychological impact, no syndromic or organ alterations were found........
View PDF View FulltextSmall Cell Carcinoma with Paraneoplastic Cushing’s Syndrome in A 23 -Year-Old A New Observation and Literature Reviewt
A 23 years old girl, without history, consulted for a neck tumefaction appeared 20 days ago, which spread then to the abdomen and lower limbs with Asthenia, dysphagia, abdominal pain, effort dyspnea. Clinical examination revealed an altered general state, obesity with centripetal fat deposition face, supraclavicular and dorsal and cervical fat pads, facial plethora, rounded face, buffalo-hump, face acne, melanodermia, capillary fragility, face, arms and legs hirsutism........
View PDF View FulltextEndoscopic Extraction of a Foreign Body: From Bench to Bedside
Rectal foreign bodies are a common and challenging finding. Here, we present the case of a man who presented to A&E with a courgette. A comprehensive radiological workup and a pre-liminary simulation of the endoscopic technique led to a successful treatment of the case........
View PDF View FulltextMandibular Localizations of Ewing Sarcomas in Children: A Rare Presentation
Ewing’s Sarcoma (ES) is a solid tumor of bone and soft tissue, affecting mainly adolescent and young adults. It is the second most common primary bone tumor in childhood and the most lethal bone tumor. ES is more common in the axial skeleton, head and neck localization is extremely rare (2 to 4%). The purpose of this article is to discuss the case of a young patient diagnosed with mandibular Ewing’s sarcoma and highlight the importance of early diagnosis........
View PDF View FulltextThe Effect of Working from Home as a Result of Covid-19
The coronavirus pandemic hit the world unexpectedly, and to respond swiftly to it, lockdown and social distancing measures had to be implemented to combat its spread. As a result, this forced changes to the working environment since many could not commute to work and have since been working remotely. Due to so many COVID-19 waves that affected different countries at various times, it proved impossible to return to the office and to work from home became entirely possible, and it also reduced the incidence of workers’ unsettlement.e.......
View PDF View FulltextMetastatic Singnet Ring Carcinoma of Unknown Primary Origin with Bilateral Chylothorax: A Case Report
Signet-ring cell carcinoma (SRCC) is defined as a poor prognosis carcinoma and it is not common. Despite the advancement of the technology, origins of about 3%–5% of metastatic tumors remain unknown. Furthermore, metastatic SRCC of unknown primary origin is very rare........
View PDF View FulltextPost vaccination -Multisystemic Inflammatory Syndrome -Adultst
Multi-system inflammatory syndrome in adults (MIS-A) is gaining recognition among adult physicians. MIS-A is a rare but important syndrome that can be difficult to distinguish from severe COVID-19. MIS- A can occur following vaccination for SARS-CoV-2 is not reported till date........
View PDF View FulltextCell Block Biopsy of Portal Vein Thrombosis for Liver Pre-Transplantation Evaluation
Major vessel invasion in patients with hepatocellular carcinoma (HCC) receiving living donor liver transplantation (LDLT) is one of the major factors for HCC recurrence. Malignant portal vein thrombosis (MPVT) is an absolute contraindication for liver transplantation (LT). However, .......
View PDF View FulltextA Giant Gastric Hyperplastic Polyp in Non-Familial Juvenile Polyposis of the Stomach: A Case Report
Juvenile Polyposis Syndrome (JPS) is a rare genetic disorder characterized by juvenile polyps of the gastrointestinal tract, which may also occur in people with no family history of the disorder. It usually involves the colorectum and more rarely the stomach. Juvenile polyps can vary in size from a few millimeters to over 5cm, and, although they have.......
View PDF View FulltextA “3-Level Block” In AVNRT
A 29-year-old woman underwent electrophysiological study for paroxysmal wide-QRS tachycardia with a left bundle branch block (LBBB) aspect (Image A)........
View PDF View FulltextCyclosporine Attenuates Covid-19: Ensnare or Victory
Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury (ALI) due to severe acute respiratory distress syndrome (ARDS). It has been proposed that initial immunological activation in SARSCoV-2 infection is necessary.......
View PDF View FulltextA Case Report of Fever in Returned Traveller
We report a rare case of severe falciparum malaria in a healthy 28-year-old gentleman in the UK. Malaria is one of the common fatal diseases in tropical countries where doctors are remarkably familiar with handling different types of malaria. In contrast, in the UK, malaria cases are not commonly seen, and all are imported cases so far. As such, clinicians in the UK may not be confident enough to tackle such kind of cases when they encounter them. In this case report, clinical presentation, how to make diagnosis and management of severe falciparum malaria based on our local hospital protocol are emphasized.......
View PDF View FulltextDermatomyositis Revealing Poorly Differentiated Neuroendocrine Carcinoma of the Gallbladder: A Case Report and Review of the Literature
To contribute to the increased understanding of the clinical features of neuroendocrine carcinoma of the gallbladder revealed by a dermatomyositis........
View PDF View FulltextPrimary Retroperitoneal Extraskeletal Mesenchymal Chondrosarcoma Involving the Colon: A Case Report and Literature Review
Extraskeletal mesenchymal chondrosarcoma (EMCS) is an extremely rare malignant tumor arising from soft tissues. It commonly occurs in the lower limbs, orbital cavity, and the central nervous system. Moreover, it is extremely rare for it to develop from a retroperitoneal location. In fact, there is no case about primary retroperitoneal ESMC involving the colon having been reported before.......
View PDF View FulltextToddler’s Fracture; False Positive Radiologic Considerations
Toddler’s fracture is an undisplaced or minimally displaced fracture, typically seen in toddlers, usually in the tibia. It is known as a difficult diagnosis to establish, considering both the clinical symptoms......
View PDF View FulltextFamiliarity with Big Data? A Comparison Between IT Department’s Staff Vs Students of the Universities
The rapid development of technology in recent decades has led to the production of a huge amount of data. One of the challenges of these analyses is the lack of specialized expertise and knowledge in this area. The purpose of this study was to compare the familiarity of IT staff and students with big data analyzes at various universities and organizations........
View PDF View FulltextPainful Encysted Adiponecrosis on the Buttock: Case Report and Etiopathogenic Discussion
Encysted adiponecrosis is a benign subcutaneous lesion characterized histologically by encapsulated fat necrosis. Our purpose was to present and discuss an atypical case of adiponecrosis revealed by a chronic hard mass of soft tissue becoming painful, asso.......
View PDF View FulltextThrombophylia and COVID-19. A Case Report of Young Man 53 Years Old with Acute Cerebral Ischemia
A 57-year-old male was admitted to our Hospital on March 2020 for SARS-Cov2 related interstitial pneumonia. Chest x-ray showed a bilateral interstitial-alveolar pneumonia and Blood gas analysis (BGA) in room air highlighted a severe respiratory failure (pO2 46 mmHg, pH 7.41). D.......
View PDF View FulltextComplement Enhances the Pathogenesis in Autoinflammation Via Induction of A Pro-Inflammatory Microenvironment
The complement system is a complex part of the innate immune system and consists of more than thirty different proteins present in the plasma and on cell membranes. Complement can be activated via three different pathways and may play a role in triggering the NLRP3 inflammasome [1].......
View PDF View FulltextCaroli Syndrome Complicated with Intrahepatic Cholangiocarcinoma
Congenital hepatic fibrosis (CHF) and Caroli disease are two rare genetic diseases. When both conditions are present simultaneously, is known as Caroli syndrome. The main complications are cholangitis and those related to portal hypertension. An uncommon complication but......
View PDF View FulltextFlavones and Phenolic Acids as Potential Inhibitor of B16F10 Melanoma Cells Growth and Modulator of Melanogenesis
Pigmentation disorders leading to discoloration or hyperpigmentary of underlying tissue occur widely and gain interest. This study is within the framework of strategies under-developing safe compounds to modulate melanognonesis pathway. Phenolic acids and flavones were tested for......
View PDF View FulltextCase Reports: Sinus of Valsalva Injury During Percutaneous Coronary Intervention and Perioperative Management
Sinus of Valsalva injury, either due to congenital defect or major traumatic events, was known to be rare. ......
View PDF View FulltextIron Deposit Central Large Nodule in Alagille Syndrome
Alagille syndrome (ALGS) is a multisystem autosomal dominant disorder attributed to defects in the Notch signaling pathway. The mutation of Jagged 1 (JAG1) gene on chromosome 20 has been identified as the underlying cause of this syndrome. In addition, the mutation of Ryanodine receptor......
View PDF View FulltextCase Report: A Clinical Dilemma of Diagnosing Recurrent Incomplete Kawasaki Disease
Kawasaki disease (KD) is one of the most common etiologies of acquired heart disease among children worldwide with unknown pathogen. Early recognition and establishing the diagnosis help the clinical pediatrics practitioner delivering intravenous immunoglobulin treatment......
View PDF View FulltextNon-Traumatic Postpartum Subdural Hematoma: A Case Report of Probable Complication of Preeclampsia
Preeclampsia is a condition that affects nearly 8% of pregnant women, usually during the second half of pregnancy (from around 20 weeks) or soon after their baby is delivered. A spontaneous subdural hematoma......
View PDF View FulltextMiraculous Treatment of Plague in The Island of Corfu from Saint Spyridon: Contribution to The History of Medicine
One of the most important Saints of the Eastern Orthodox Church is Saint Spyridon, Bishop of Tremithus of Cyprus, patron saint of Corfu.......
View PDF View FulltextGravitation - Flat Power Field
A new principle of origin and the nature of the action of gravity forces are proposed. Forces of universal attraction have plane-symmetrical directions.......
View PDF View FulltextDecisions During Covid-19 Pandemic in A Middle-Income Country: A Case Report of Fast-Growing Breast Cancer in A Pregnant Woman
In this Brazilian breast cancer (BC) case report, we described a pregnant woman diagnosed with BC during the beginning of COVID-19 pandemic. The uniqueness of the case reported is related not only to the......
View PDF View FulltextCelidocranial Dysostosis Followed for 25 Years. Presentation of A Case
Cleidocranial Dysostosis is an autosomal dominant scale dysplasia. We present a case of Cleidocranial Dysostosis of a female patient with deformities in the development of the osteomyoarticular system due to clavicular agenesis......
View PDF View FulltextClinical Decision Making of Greek Nurses Working in Health Centers, Emergency Rooms, Medical-Surgical Clinics and ICUs
Clinical decision making is an integral part of nursing science and daily clinical nursing practice............
View PDF View FulltextClinical Outcomes of Patients with Advanced Solid Tumors of Cutaneous Capillary Hyperplasia Following Treatment with Camrelizumab: A Retrospective Case-Control Study
To investigate the difference of clinical outcomes between patients with and without reactive cutaneous capillary endothelial proliferation (RCCEP) after camrelizumab treatment.............
View PDF View FulltextAn Extremely Rare Malignant Glomus Tumor of the Breast: A Case Report and Review of the Literature
Glomus tumor is a rare neoplasm that originates from the glomus body in the dermis or subcutaneous of the extremities. In rare instances, glomus tumors have been observed in visceral organs. Here, we report an extremely rare case of primary malignant breast glomus tumor............
View PDF View FulltextEffect of Inhaled Nitric Oxide on Acute Cor Pulmonale in Covid-19 Pneumonia Associated Acute Respiratory Distress Syndrome; A Case Report
Theoretically, inhaled nitric oxide can be effective on the treatment of acute cor pulmonale. However, the efficacy during acute respiratory distress syndrome has not been proved.............
View PDF View FulltextPET Imaging Performed Immediately After COVID 19 Vaccination: What A Radiologist Should Know
An interesting article titled “Frequency and Characteristics of Nodal and Deltoid FDG and 11-C Choline uptake on PET imaging performed after COVID-19 vaccination” was recently published in American Journal of Roentgenology. In this Editorial, I will like to discuss important pertinent findings of this study. 67 patients were recruited (66 had undergone PET/CT and 1 had undergone PET/MRI; FDG in 54 and............
View PDF View FulltextRecurrent Carcinosarcoma of the Breast: A Case-Report
Carcinosarcoma or metaplastic carcinoma of the breast with mesenchymal differentiation classified as subtypes of metaplastic breast carcinoma (MBC) is a rare and highly aggressive tumor. Metastasis to soft tissue and bone is a challenging issue to make a diagnosis because of similarity to the mesenchymal tumor.............
View PDF View FulltextMalignant Metastatic Struma Ovarii: A Case Report with Tyrosine Kinase Inhibitor Treatment and Long Follow Up
Metastatic malignant struma ovarii (MMSO) is a very rare disease (incidence of less than one case in 10 million females annually in the United States). Its rarity results in paucity of data regarding diagnosis, treatment, and follow up. Herein, we describe a case of a 14-year old female who presented with malignant struma ovarii that............
View PDF View FulltextSchizophrenic Patient with Drug Induced Liver Injury Initially Misdiagnosed as Wilson’s Disease with Final Diagnosis of Celiac Disease
Associations between psychiatric symptoms in patients with celiac disease have been described in the literature. We report the case of a schizophrenic patient initially suspected of Wilson disease that was diagnosed with celiac disease in our hepatology unit.............
View PDF View FulltextPrimary Cardiac Angiosarcoma Diagnosed by 3D Transesophageal Echocardiography Guided Endomyocardial Biopsy – Case Report
Cardiac angiosarcomas are uncommon, primary malignant cardiac tumors, characterized by an aggressive local growth within the myocardial structures. The majority occur in the right atrium, and at the moment............
View PDF View FulltextRural Healthcare in Light of a Multinational Pandemic: A Global Perspective
Rural healthcare recently came into international spotlight, with recent reported influx of the COVID-19 into rural regions. This article focuses on susceptibilities of the rural population to pandemics and mitigating measures to prevent formation of disease epicentre............
View PDF View FulltextSyringoma
Syringoma is a benign eccrine sweat gland tumor affecting mostly females at puberty projected with multiple soft papules usually 1-2 mm in diameter. During puberty, syringoma appears among females; it is presented as multiple soft papules, 1-2 mm in diameter, as a benign eccrine sweat gland tumor. The sites of predilection are lower eyelids, and cheeks. The regions of tendency are cheeks and lower eyelids. Syringoma of the vulvar is a rare disorder few cases of which have been reported in literature.........
View PDF View FulltextWhole Blood Gene Expression Profiling in Response to Treatment for Septic Shock: A Case Report
Septic shock develops as a result of the rapid progression of sepsis due to the massive release of proinflammatory mediators, and is characterized by severe hypotension and tissue hypoxia. While early goal-directed therapy (EGDT) and polymyxin B direct hemoperfusion (PMX-DHP)..........
View PDF View FulltextSeverini – From Divisionism and Futurism
In 1900, Gino Severini he met the painter Umberto Boccioni. Together they visited the studio of Giacomo Balla, where they were introduced to the technique of Divisionism, painting with adjacent rather than mixed colors and breaking the painted surface into a field............
View PDF View FulltextThe Nature of Primary Care
It’s important to define what Primary Care is and the priorities and context in which Primary Care works...........
View PDF View FulltextMegacalycosis with Ipsilateral Segmental Mega-Ureter - A Rare Entity
Congenital megacalycosis of Pugivert is a rare clinical entity which denotes presence of dilated calyces most often without any functional abnormality and Segmental mega-ureter implies large, focal segmental ureteral ...........
View PDF View FulltextThe Assessment of the Whole-Body Vibration on Health Effects in Automobile Assembly Line Worker in South Korea
In general, whole-body vibration is one of the potential contributors to the development of back disorders of workers. In particular, it is thought that workers at the automobile assembly line are exposed..........
View PDF View FulltextCognitive Consequences After Traumatic Brain Injury (TBI)
A traumatic brain injury (TBI) can cause temporary dysfunction of brain cells. More severe craniocerebral injuries can lead to bruising, perforation and tissue rupture, bleeding, and other physical damage to the brain that can lead to long-term complications or death (Bigler, 2016)............
View PDF View FulltextNeurocysticercosis in an Immigrant, A Case Report from a Tertiary Hospital in Uganda
Neurocysticercosis (NCC) is one of the seven neglected endemic zoonoses targeted for elimination by the World Health Organization. NCC is a common primary cause of preventable epilepsy in many developing countries caused by the platyhelminth...........
View PDF View FulltextPatients with Multiple Sclerosis and Short-Term Memory Difficulties
Μemory by itself as a function, loses its capabilities with a normal deterioration. However, there are acquired conditions that negatively affect the functions of memory, resulting in dysfunction of its stages. Thus possible damage to the structures of the hemisphere that controls............
View PDF View FulltextRectal Haematoma After Colonoscopy and Polypectomy. Presentation and Management
Mural haematoma after colonoscopy and polypectomy has been reported infrequently. We report a case of rectal haematoma that required prolonged hospitalization and surgical intervention. The literature on this complication is reviewed.............
View PDF View FulltextA Questionnaire On Adoptive Cell Therapy Among Syrian Medical Students
Adoptive Cell Therapy (ACT) is a type of immunotherapy, in which immune cells are implanted in patients to help them cure diseases (such as cancer). It is a new technique that has proven its effectiveness in treating............
View PDF View FulltextDelayed Post-Traumatic Splenic Rupture After Fall in a Hemodynamically Stable Patient with Undiagnosed Pancreatic Malignancy Which Occluded Both Splenic Artery and Vein
The spleen, due to its anatomical position, is the most frequently injured organ of the abdomen due to blunt trauma. Herein we describe the case of a 59-year-old female patient who fell from the same height and five days later she complained of persistent pain in the left hypochondrium.............
View PDF View FulltextAn Atypical Presentation of Primary Tubercular Psoas Abscess Presenting as Groin Pain
Psoas abscess, a collection of pus in the iliopsoas compartment is an unusual lesion that is unfamiliar to many medicine specialists, which can make an accurate and timely diagnosis problematic. The symptoms associated with this disorder often involve hip pain instead of abdominal or............
View PDF View FulltextModifield Desarda Repair and Hernioplastia Lichtenstein Repair For Inguinal Hernia
The objective of this study is to compare the outcomes of Modified Desarda repair no mesh and Lichtenstein repair for inguinal hernia. ............
View PDF View FulltextOrthopedic Clinical Manifestations of Ectodermal Dysplasia. Case Presentation
Ectodermal dysplasias represent a heterogeneous group of alterations, characterized by the abnormal development of embryological derivatives of the ectoderm.We present a patient who, upon examination of the osteomyoarticular system, presents intense rotation of the lower limbs with the toes backwards,........
View PDF View FulltextIntraventricular Neurocytoma a Series of 10 Cases and Review of Literature
Central neurocytoma (CN) is a benign brain tumor of intraventricular site; According to the World Health Organization (WHO) 2016, it is categorized as grade II. We report a series of 10 cases that were diagnosed with CN by immunhistochemistry of surgical specimens at our hospital. ............
View PDF View FulltextA Build Up of Seizure Prediction and Detection Software: A Review
Neurological diseases are much often due to our stressed daily life, and epilepsy is considered as a second cause of hospitalization in neurological illness. It is about 30% of epileptic cases where medicine would not stop or control seizure; hence, a surgical intervention ............
View PDF View FulltextA Peculiar Case of Stupor and Muscular Stiffness Associated with Hyperkalemia
A man 66 years old, presented to the emergency with stupor and lethargy. His relatives recorded that patient had several episodes of diarrhea prior days, widespread muscle pain, walking difficulties with loss of balance and became progressively weaker and confused. His medical history included bipolar disorder, diabetes mellitus, obesity, smoking status,............
View PDF View FulltextOne Stage Operation in Bilateral Pulmonary and Spleen Hydatid Cyst in Uncommon Localization
The lung is the second most commonly organ which affected after liver chyst by echinococoss, and the bilateral involvement of lung is rare and Primary spleen hydatid cysts are very rare seen even in endemic country. We report the case of a 32-year-old man who presented with left thoracic and left upper abdominal pain and dry cough evolving for four months. Thoracic CT scan after injection of the contrast media. ............
View PDF View FulltextEffect of Resistance Exercises with Salvia Officinalis Supplementation on the Response of Some Bio-Hormones in Overweight Male Students
The aim of this study was the effect of resistance exercises with sage supplementation on the response of some bio-hormones in overweight male students. ............
View PDF View FulltextCoccidioidomycosis Meningitis in an Immunocompetent Worker: A Case Report
“If you work in the dry dust of Arizona or California central valley Surely be warned about fever, or deadly head-aches from all those Cocci!!”............
View PDF View FulltextExercise Prescription for Hypertension
The importance of physical exercise in preventing, treating and controlling hypertension has been the subject of enormous attention during the past several decades. Nearly one third of American adults have been diagnosed with high blood pressure and millions more have pre-hypertension. Cardiorespiratory fitness has an important non-pharmacologic role in hypertension treatment and prevention, yet one in three Americans does not engage in leisure-time physical activity. ............
View PDF View FulltextDuchenne Muscular Dystrophy Improved Clinically by Homeopathy: A Case Report
Muscular dystrophy is a group of multiple inherited diseases that damage muscles with time and causes a partial or complete loss of movement. It happens due to the lack of protein dystrophin, which is important............
View PDF View FulltextProtection of the External Branch of the Superior Laryngeal Nerve in Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA): An Observational Study
Avoiding injury of the external branch of the superior laryngeal nerve (EBSLN) is one of the major challenges during thyroid surgery, especially in transoral endoscopic thyroidectomy vestibular approach (TOETVA). This study aimed to investigate the protective strategies of the EBSLN during TOETVA.............
View PDF View FulltextRole of 18F-FDG PET-CT in CNS Lymphoma- A Case Report
The actual role of 18F-FDG PET/CT in evaluating primary brain lymphoma is still an open issue. Brain lymphoma usually show elevated 18F-FDG uptake, often higher than other brain tumors or inflammatory processes............
View PDF View FulltextPrevalence of Cns Tumors and Histological Recognition in the Operated Patients: 10 Years Experience
Tumors of the central nervous system consist of a heterogeneous group of neoplasms of great histological diversity. Despite the increasing prevalence of these tumors in developing countries, some places like Yemen do not have representative studies showing the true impact of these tumors on our population.............
View PDF View FulltextAsymptomatic Right Atrial Lipoma in A 42-Year-Old Patient : A Case Report
Lipoma, a common soft tissue tumor composed of mature adipose tissues, can occur in any part of the body with fat. Accounting for 8.4% of primary heart tumors [1], the lipoma in the heart is rare, and the most common sites are the right atrium, left ventricle, and pericardium [2,3]............
View PDF View FulltextEffect of Resistance Exercises with Salvia Officinalis Supplementation on the Response of Some Bio-Hormones in Overweight Male Students
The aim of this study was the effect of resistance exercises with sage supplementation on the response of some bio-hormones in overweight male students. ...........
View PDF View FulltextDiagnostic Pitfalls of Eccrine Porocarcinoma with Extensive Squamous Differentiation
Eccrine porocarcinoma is an extremely rare malignant skin tumor. Furthermore, because it has clinicopathologic characteristics similar to other skin adnexal tumors, it is often difficult for clinicians and pathologists to diagnose.............
View PDF View FulltextA Significant Response to Anakinra in Management of Adult Onset Still’s Disease: A Case Report
Adult Onset Still’s Disease (AOSD) is a rare rheumatological condition that is characterized by a clinical triad of (daily spiking Fever, arthritis and rash) and a biochemical triad (hyperleukocytosis with neutrophilia, hyperferritinemia and abnormal liver function test). ............
View PDF View FulltextLipoesclerosing Myxofibrous Tumor: When The Site It Is Important
Liposclerosing Myxofibrous Tumor (LSMFT) is a benign fibro-osseous lesion with distinct clinical and radiological features, characterized by a complex mixture of histologic elements, including its fibrous dysplasia-like features, lipoma, myxofibrous tissue, ischemic ossification, xantoma features and pseudo- Paget’s bone patterns. Most lesions are discovered incidentally, but patients can present with bone pain or fracture.............
View PDF View FulltextClinical and Genetic Analysis of Multi-System Pseudohypoaldosteronism Type 1 Caused by a Novel Splice Site Mutation of the Beta Subunit Gene of Epithelial Sodium Channel (Enac)
This article aims to provide a comprehensive review of the clinical features and genetics basis of multi-system pseudohypoaldosteronism type 1 caused by SCNN1B gene mutations............
View PDF View FulltextCompatibility Between Hyperuricemia, Hypertension, Diabetes Mellitus, and Hyperlipidemia- Study Case
Hyperuricemia is a disease that arises as a result of a defect in the metabolism process, leading to an increase in its production and accumulation in the blood, with the inability to excrete it in the urine through the kidneys. It has been found that people who suffer from a problem in metabolism, such as patients with diabetes or high blood fats, or patients with high blood pressure suffer from high uric acid. In this article, we find that a woman suffering from diabetes and high blood pressure, by measuring blood lipids and uric acid, their rates were high.............
View PDF View FulltextA Review for Diagnostic Inaccuracy of Pure Ductal Carcinoma Insitu in Multiple Fibroadenomas and Axillary Nodal Involvement
Fibroadenomas (FA), are common benign tumor of the breast, can be treated with simple excision. Breast cancer arising within FA is a rare phenomenon. ............
View PDF View FulltextPersistent Thorasic Airleak After İmplantation of a Subcutaneously Port-Chamber Catheter
Persistent thorasic airleak is a rare complication after totally implantable port-chamber catheter(PCC) implantation. Prolonged airleaks are undesirable because they prolong the duration of chest tube drainage with associated pain and risk of infection and they also prolong hospitalization. In cancer patients, it is important to prevent this rare complication and to recognize it early if it does occur.............
View PDF View FulltextA Rare Case of EBV Infection Mimicking Polymyositis with Hemophagocytic Syndrome-Diagnostic Challenges and Pitfalls
To describe the clinical evolution of a case of Epstein-Barr virus infection simulating polymyositis from initial visit to final death............
View PDF View FulltextThe Role of Strain Echocardiography in the Early Diagnosis of AL Type Cardiac Amylodiosis: A Case Report
Cardiac amyloidosis is a progressive cardiomyopathy that results from the accumulation of disrupted endogenous proteins in the heart in the form of amyloid fibrils. Diagnosing cardiac amyloidosis is a difficult process............
View PDF View FulltextIMRT Combined with Cetuximab for Locally Recurrent Nasopharyngeal Carcinoma Case and Literature Review
Objective to explore the efficacy and safety of IMRT combined with ............
View PDF View FulltextAcute Macular Pucker After Silicone Oil Removal After Reattachment Surgery for Giant Retinal Tear Detachment
Acute macular pucker is an uncommon entity of epiretinal membrane due to proliferative vitreoretinopathy, and typically presents with rapid progression of vision loss and metamorphopsia over 2 weeks to 3 months after retinal tears or detachment. We report an atypical case of acute macular............
View PDF View FulltextMyocardial Infarction on the Background of Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is the most common chronic inflammatory arthritis under 16 years of age but unlike rheumatoid arthritis, the risk of cardiovascular diseases including Myocardial Infarction (MI) in............
View PDF View FulltextFalse Negative Results in Prenatal Aneuploidy Invasive Testing: Two Case Reports
Over the last decade, molecular methods, such as chromosomal microarray and Bacs-On-Beads assay, have been shown to improve the detection rate of chromosomal abnormalities. Nonetheless, conventional cytogenetics methods, such as FISH and karyotyping, are still useful tools and should not be dismissed.............
View PDF View FulltextFrequency of Common Causes of Severe Hyperbilirubinemia in Neonates Leading to Exchange Transfusion
Severe hyperbilirubinemia can cause neurotoxicity called kernicterus which is a neurological syndrome resulting from the deposition of unconjugated bilirubin in the basal ganglia and brainstem nuclei due to which patients suffer from long term morbidities consisting...........
View PDF View FulltextThe Intra and Extra Cranial Veins in Relationship with Chronic Migraine: Electroencephalogram Modifications Induced by Balloon Venoplasty
Chronic Migraine (CM) is characterized by recurrent head pain often associated with electroencephalogram (EEG) abnormalities and asymmetry of intracranial venous circulation. Migraine is a symptom of the Chronic Cerebrospinal Venous Insufficiency (CCSVI).............
View PDF View FulltextEllis Van Creveld Syndrome: An Unusual Presentation at Birth
The Ellis-van Creveld Syndrome, also known as Chondroectodermal dysplasia, is a skeletal and ectodermal dysplasia which is characterized by the narrow chest, short ribs with congenital heart defects like ASD and polydactyly. It is an extremely rare condition. An unusual case of Ellis............
View PDF View FulltextSpontaneous Muscle Hematoma in Patients with COVID-19: Experience of 3 Cases
The overall bleeding complication rate in patients receiving anticoagulation, whether in COVID-19 or non-COVID-19 patients is low, only slightly higher in critically ill patients and those receiving a therapeutic dose of anticoagulants. Among bleeding complications, spontaneous muscle hematomas (SMH) are particularly uncommon, often overlooked or misdiagnosed.............
View PDF View FulltextHepatic Portal Venous Gas in 91-Year-Old Patient with Good Long-Term Prognosis: A Case Report
Hepatic portal venous gas(HPVG) are rarely seen. Case: A 91-year-old male patient was referred to our hospital with chief complaints of severe sudden abdominal pain. Hepatic portal venous gas (HPVG) was............
View PDF View FulltextTerapeutic of the Use of Chewing Gum in their Different Presentations to Minimizel to Inertia and Sleep Deprivation
Sleep is defined as the natural, periodic, and reversible decrease in perception of the external environment, with the preservation of a certain degree of reactivity to the environment and autonomous functions. Sleep consists of 2 phases, REM phase and NREM phase, these phases alternate at night in the form of five to six cycles; of which the NREM phase is 75% present and the REM by 25%. ............
View PDF View FulltextA Rare Cause of Biliary Obstruction Caused by Egg of Fasciola Hepatica Mimicking Biliary Duct Stone or Rupture of Liver Hydatid Cyst
Fasciola hepatica is an endemic parasitic disease in Iran and some countries in the world. The humans are accidentally infected by Fasciola in the life cycle. The definitive host is sheep. When human infected, the presentations are in two shape: acute or hepatic and chronic or biliary shape. When the flukes or eggs enter the bile ducts,............
View PDF View FulltextGingival Epidermal Inclusion Cyst– A Rare Entity with Literature Review
Epidermal inclusion cysts or epidermoid cysts are benign cystic lesions rarely occurring in the oral cavity. These cysts represent less than 0.01% of all oral cavity cysts. Most commonly involved location in the............
View PDF View FulltextSuperior Mesenteric Artery: Clinical Case
Acute mesenteric ischemia refers to a sudden onset of intestinal hypoperfusion, which can be due to a reduction or cessation of arterial inflow leading to cellular damage, intestinal necrosis and eventually death if untreated [1].............
View PDF View FulltextRepot a Rare Case of Achalasia Which Present as Mediastinal Cysts or Masses
Achalasia is a rare motility disorder of the esophagus and present by failure of lower esophageal sphincter (LES) relaxation during swallow. This rare disease of esophagus with it symptoms can mimic a variety of common illnesses of esophagouse,but not the mediastinum............
View PDF View FulltextGastric Necrosis – An Untold Catastrophe in Splenectomy: How we Manage in a Surgical District Hospital
Gastric necrosis post splenectomy carries a high risk of mortality and should be identified and diagnosed early. It is a rare event, only reported in less than............
View PDF View FulltextSiringomielia, Report of A Clinical Case and Bibliographic Review
Syringomyelia is a pathological affectation of the spinal cord, which consists of a central cavitation, which mainly affects the cervical area............
View PDF View FulltextYolk Sac Tumor as a Rare Cause of Esophageal Stricture in a 5-Year-Old Girl: A Case Report and Review of Literature
Yolk Sac Tumor (YST), which most frequently arises in the gonads as a type of germ cell tumor, is rare in children but is highly malignant. There are a number of diagnostic tools applied for YST, such as US, CT, Magnetic Resonance Imaging (MRI) and histopathological analysis.............
View PDF View FulltextResearch on Agricultural Structure Under the Impact of the COVID-19 Pandemic
The adjustment of the agricultural industrial structure is a process of adapting to the laws of market development and reflecting a country's resource endowments and comparative advantages. After the outbreak of the COVID-19............
View PDF View FulltextIntervention of Sleep Quality in The Onset of Concomitant Symptoms in Hospitalized Patients
This work allows us to observe the quality of sleep and respect for circadian cycles as very important factors in the development of multiple diseases and in various specialties, which affects in the rapeutic methods, both in external and hospitalized patients and the variety of symptoms that can be observed, through a practical survey method, with the main objective of contributing to the awareness of the importance of sleep hygiene measures and their improvement in the quality of life of patients.............
View PDF View FulltextRelationship of Smartphone Addiction with Hand Grip Strength and Upper Limb Disability
Due to evolution of technology smart phone has become our necessity. Where on one hand it has made our lifestyle more comfortable in............
View PDF View FulltextDermoid Cyst of the Spermatic Cord Mimicking Incarcerated Inguinal Hernia
Dermoid cyst of the spermatic cord is a very rare clinical entity with only 6 cases reported in the literature so far. We describe an extremely rare case of a large dermoid cyst of the right spermatic cord measuring............
View PDF View FulltextPancreatitis Associated with Covid-19 And Relationship with A Healthy Lifestyle
In December of 2019, a severe acute respiratory syndrome emerged in Wuhan and rapidly spread through China subsequently was declared a pandemic in March 2020............
View PDF View FulltextTransverse Myelitis in a Patient with COVID-19: A Case Report
There has been growing evidence of COVID-19 potentially causing a wide range of neurological abnormalities from as mild as anosmia............
View PDF View FulltextDentoalveolar Fracture with Dental Pulp and Periodontal Involvment Management: A Review Article
Dentoalveolar fractures is common fracture in accident, could be results from motor vehicle accidents, interpersonal violence, falls, sports, bicycle accidents, and other unusual causes. While motor............
View PDF View FulltextImprovement of Diffuse Axonal Damage and Sinking Flap Syndrome Post Craneoplasty
The trephined, craniotomized, or sunken flap syndrome encompasses neurological manifestations associated with skin flap depression and is............
View PDF View FulltextBreast DCE-MRI Segmentation for Lesion Detection Using Grammatical Fireworks Algorithm
Breast DCE-MRI segmentation and lesion detection is a crucial image analysis task for cancer detection and tissue characterization. In this paper, ............
View PDF View FulltextCauses and Consequences of Back Pain
Back pain is one of the most common forms of body pain. Back pain can be felt in many ways. It can range from mild to severe pain that can affect the ability to move. Back pain can be felt as muscle pain, stabbing pain............
View PDF View Fulltext"Excessive Daytime Sleepiness and Sleep Quality in Doctors and Nurses of The Regional Military Specialty Hospital" Guadalajara. 2019.
Detect sleep disorder Excessive Daytime Sleepiness and bad sleepers in doctors and nurses of the Guadalajara Regional Military Specialty Hospital. ............
View PDF View FulltextA Novel Method of Laparoscopic Approach in a Giant Bladder Diverticulum with Renal Cell Carcinoma "Double Trouble"
Congenital diverticular are rare and caused from weakening of the bladder mucosa with the entire wall of the diverticulum. Giant vesical diverticulum............
View PDF View FulltextDepression and Anxiety Frequency in Patients Hospitalized on the Guadalajara Regional Military Hospital in the Month of April 2019
Observe and Identify patients that presented depression and anxiety using the Hospital Anxiety Diagnosis Scale (HADS), Zung & Conde scale and ............
View PDF View FulltextEffects of Regular Physical Activity in Water with and Without Ginger Supplementation on Adiponectin in Obese Female with Breast
The aim of this study was to determine the Effects of regular physical activity in water with and without Ginger supplementation on adiponectin and related biochemical markers in obese female with breast cancer............
View PDF View Fulltext"Knowledge of the abord Aje De La Cefalea Tensional by First Contact Doctors at the Regional Military Specialty Hospital in Guadalajara, Mexico"
Headache is one of the most common reasons for consultation where people go to emergency services. It is estimated that at least one-third of the population between the age of 18 and 65 has ever suffered from a headache...........
View PDF View FulltextEsophageal Xanthoma in Barrett’s Esophagus Associated with Non-Steroidal Anti-Inflammatory Drugs Use
Xanthomas are benign tumor-like lesions, composed of accumulation of foamy lipid- laden histiocytic cells. Usually, xanthomas appear in the skin and tendons, while visceral location is uncommon. These lesions can be found anywhere along the gastrointestinal tract, commonly in the stomach and colon............
View PDF View FulltextIchthyosis Prematurity Syndrome: A Rare But Easily Recognizable Ichthyosis
Ichthyosis prematurity syndrome [IPS, OMIM608649] is a rare autosomal recessive disorder characterized by the clinical triad of premature birth, ichthyosis, and neonatal asphyxia [1]. It is caused by a mutation in SLC27A4 (solute carrier family 27 member 4, which encodes fatty acid transport protein 4 [FATP4]) [2]. ...........
View PDF View FulltextA Case Report of Multiple Lymph Node Metastatic Adenocarcinoma Without Primary Lesion (Probable Source of Salivary Glands)
Salivary gland cancer is a rare malignant tumor of the head and neck. We provide a rare case, a malignant and poorly differentiated adenocarcinoma with no clear primary lesion and multiple regional lymph node metastasis. In terms of treatment, chemotherapy, targeted therapy and immunotherapy were explored and positive effects were achieved............
View PDF View FulltextReduce the Burden of Polypectomy with Predictable Juvenile Polyp
Juvenile polyps make up 70 to 80% of pediatric colon polyps, of which 60 to 70% are solitary. The average age of diagnosis of polyps is from 2 to 5 years............
View PDF View FulltextA Congenital Diaphragmatic Hernia and 46,XX Disorder of Sex Development Caused by a WT1 Pathogenic Variant
WT1 is an important gene in gonadal differentiation process, especially in the male differenciation. It is known in some syndromic and non-syndromic pathology. This gene is associated with under-virilization in 46,XY patient............
View PDF View FulltextChronic Maxillary Atelectasis and Silent Sinus Syndrom: Report of Three Cases and Literature Review
Chronic Maxillary Atelectasis (CMA) and Silent Sinus Syndrome (SSS) are conditions that may lie on the same clinical spectrum, since both have similarities in pathophysiology, clinical findings and treatment, although the...........
View PDF View FulltextMesenchymal Hamartoma: A Review of Literature
Mesenchymal Hamartoma is a rare, benign osseous tumor that typically involves the rib cage and presents during the first year of life. There is a case of this tumor originating in the cervical spine, described in literature. I document a brief literature review. In this review, there are not figures and outcomes...........
View PDF View FulltextOlder People with Chronic Diseases: A Vision of the Future
The Spanish Constitution in article 43 establishes the Right to Health and its development, through the General Law on Health, urges the National Health System (SNS) and the Health Services of the Autonomous Communities (CCAA), to develop Comprehensive Plans or Regional Health Plans...........
View PDF View FulltextA Rare Case of Co-Infection with Pulmonary Tuberculosis and Palatal Actinomycosis
Palatal actinomycosis is an infection rarely described in literature, especially in the form of co-infection with pulmonary infection. We report a case of 55 year old male who reported in our O.P.D. with palatal fistula communicating oral cavity to nasal cavity. Patient had nasal regurgitation...........
View PDF View Fulltext“On the Detection of cTnI A Comparison of Surface-Plasmon Optical, Electrochemical, and Electronic Sensing Concepts”
“Cardiovascular diseases (CVDs) are the number one cause of death globally, taking an estimated 17.9 million lives each year. CVDs are a group of disorders of the heart and blood vessels and include coronary heart disease,...........
View PDF View FulltextImmunology Pathway of During Autoimmune Disease: A Review Article
Dermatitis herpetiformis or also known as duhring disease is a rare autoimmune vesicobulosa disease, specific and recurrent chronic in nature and has a relationship with celiac disease and gluten-sensitive enteropathy. The diagnosis of dermatitis herpetiformis is based on a combination of physical examination, routine histopathological examination, immunofluorescence ...........
View PDF View FulltextA New Life, Unfortunately in A World Of Darkness
Acute pulmonary embolism is a form of venous thromboembolism that is common and sometimes fatal. Submassive PE compromises of at least 20% of all acute cases of pulmonary embolisms. It has been shown to have an up to 5% in hospital mortality rate [1]............
View PDF View FulltextAllergic Reactions to Covid19 (Sars-Cov-2) Vaccine
The recent approval of various covid vaccines will result in massive immunization of the public with these vaccines. Cases of allergic reactions such as rashes, urticaria, anaphylaxis have been reported worldwide. The following is a summary, from an allergist’s perspective, of the components found to be present in situations where the patient has experienced an allergic reaction to the Covid 19 vaccine............
View PDF View FulltextCase Report of General Anesthesia After Asymptomatic SARS-Cov-2-Infection
From our experience and description of colleagues, SARS-CoV2-patients who are ventilated on intensive care unit (ICU) require complex sedation............
View PDF View FulltextThe Incidence Rate of Vancomycin-Induced Thrombocytopenia in Orthopedics: A Single-Center Retrospective Case Series
Vancomycin has been an indispensable alternative for the treatment of severe and complicated infections, especially in orthopedics department. However, as a severe adverse drug effect, vancomycin-induced thrombocytopenia (VIT) has not attracted enough attention. The objective of the research was to analyze the incidence rate of VIT in orthopedic patients...........
View PDF View FulltextUncommon Cause of Gastrointestinal Bleeding
Gastric antral vascular ectasia is an uncommon cause of chronic gastrointestinal bleeding or iron deficiency anaemia [1]. The condition is associated with dilated small blood vessels in the antrum, or the last part of the stomach. It is also called watermelon stomach because streaky long red areas that are present .....
View PDF View FulltextSexual Function and Dysfunction among Patients with Systemic and Auto-Immune Diseases
Systemic autoimmune diseases affect various organs and they can determine sexual dysfunction in females and males patients particularly with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic .....
View PDF View FulltextComments on Article Continuous Shortwave Diathermy with Exercise Reduces Pain and Improves Function in Lateral Epicondylitis More Than Sham Diathermy: A Randomized Controlled Trial
I read very carefully the article “Continuous shortwave diathermy with exercise reduces pain and improves function in Lateral Epicondylitis more than sham diathermy: A randomized controlled trial.” by Babaei-Ghazani et al. (2020) [1] and I would like to congratulate the authors because this was the first trial to investigate the effectiveness of continuous shortwave diathermy (CSWD) in Lateral Epicondylitis (LE) patients. However, I would like to comment the following:.....
View PDF View FulltextIntramural Hematoma of Esophagus After Lifting a Heavy Sack of Rice Which Mimicking Cardiovascular Disorder
We report here a case of an intramural hematoma of the esophagus. The extension of this was from cervical esophagus to lesser curvature of stomach intramural hematoma......
View PDF View FulltextA Wandering Atrial Pacemaker in Inferior Wall Infarction. Escape or Survival Rhythm? A Case Reports
Coronary sinus rhythm is an ectopic atrial rhythm supposedly originating from a pacemaker at the mouth of the coronary sinus; recognized in the electrocardiogram .....
View PDF View FulltextComments on Article Continuous Shortwave Diathermy with Exercise Reduces Pain and Improves Function in Lateral Epicondylitis More Than Sham Diathermy: A Randomized Controlled Trial
I read very carefully the article “Continuous shortwave diathermy with exercise reduces pain and improves function in Lateral Epicondylitis more than sham diathermy: A randomized controlled trial.” by Babaei-Ghazani et al. (2020) [1] and I would like to congratulate the authors because this was the first trial to investigate the effectiveness of Continuous Shortwave Diathermy (CSWD) in Lateral Epicondylitis (LE) patients. However, I would like to comment the following:.....
View PDF View FulltextA Chest Contusion Following Car Accident, In Obese Patient Suffering from Obstructive Sleep Apnea
We describe the case of a 50 years old male patient, who, affected by Obesity and OSAS, came to our ambulatory for dyspnea, shortness of breath and astenia. The subject described that the week before had a car accident and was taken to the ER, where received a chest x-ray which resulted negative......
View PDF View FulltextProphylaxis Against COVID-19: A Possible Way of Effective Control Against COVID-19
COVID-19 emerged in the later part of 2019 is a public health emergency of international concern. Though definite treatment and vaccine against the Coronavirus are not available, yet COVID-19 prevention and prophylaxis are important to appease the pandemic burden. An effective prophylactic agent will prevent disease in high-risk groups, e.g., medical professionals managing COVID-19 patients. .....
View PDF View FulltextNon-Conventional COVID Treatment Methods 19
In bioelectronic terms, the organism is understood as an integrated circuit of biological piezo, pyroelectrics, ferromagnets and semiconductors, filled with bioplasm and managed electronically by quantum processes......
View PDF View FulltextA LGI1 Mutation (C.263 T>A P.Leu88*) Identified in a Chinese Patient with Epilepsy: A Case Study
To investigate the genetic causes of a 13-year-old Chinese female proband with epilepsy......
View PDF View FulltextAtypical Haemolytic Uraemic Syndrome with Isolation of Aepec in the Stool Culture
Thrombotic Microangiopathy (TMA) is based on a vascular endothelial injury and is characterized by microangiopathic hemolytic anemia, thrombocytopenia and organ malfunction of variable intensity. The etiology includes Thrombotic .....
View PDF View FulltextPeripheral Arterial Embolism from the Mural Abdominal Aortic Thrombosis
We present two men suffering from critical limb ischemia (Fontaine gr. IV.) due to mural aortic thrombosis with peripheral arterial embolism. Duplex ultrasound was adequate for the diagnosis in both cases. CTA only confirmed the.....
View PDF View FulltextReactive Arthritis Due to Influenza Virus in a Male Patient: A Case Report
Myalgias and arthralgias are a common symptom of influenza viruses’ infection. Reactive arthritis due to influenza vaccination has been described. Here we report the case of a 40-year-old Greek patient with free history.....
View PDF View FulltextA Germline Mutation of Gene ATM P.C1899* is Associated with Family History of Multiple Cancers in a Family in Yunnan Province, China
Ataxia-Telangiectasia Mutation (ATM) is a well-known gene on chromosome 11q that plays a role in cell cycle checkpoints and DNA damage responses. Heterozygous germline mutations in ATM are....
View PDF View FulltextScalloping and Mosaic Pattern of the Duodenum
A 65-year-old female patient was admitted to the gastroenterohepatology outpatient clinic due to diarrhea, exhaustion and weight loss of about 6 kg complaints in the last year. Her medical history revealed that.....
View PDF View FulltextThe Role of the Pharmacist in Patient Care (Book Review)
Most people on the outside of the health care profession are not familiar with this new role of the pharmacist. The general public has created a stereotypical pharmacist's .....
View PDF View FulltextPrimary Neuroendocrine Carcinoma of the Appendix: A Case Report
Neuroendocrine Carcinoma (NEC) of the appendix is extremely rare and its clinical characteristics and treatment strategy have not been well established......
View PDF View FulltextGlioblastoma Multiforme in The COVID-19 Era: How Italy Managed to Surgically Treat the Neuro-Oncological Patient Despite the Pandemic
The wave of SARS-CoV-2 is affecting every country in the world in a more or less homogeneous way and one wonders what is the best therapeutic option for the infected patient diagnosed with Glioblastoma Multiforme.....
View PDF View FulltextA Rare Case of Tumid Lupus Erythematosus with Unilateral Linear Distribution in A Young Child
Tumid Lupus Erythematosus (TLE) as a rare variant of Cutaneous Lupus Erythematosus (CLE) is characterized by edematous, urticarial-like annular papules and plaques......
View PDF View FulltextTobacco Is Not the Only Risk Factor for COPD: Let's Not Forget the Genetic Factor!!!
Chronic obstructive pulmonary disease (COPD) is a major health problem as it causes increasing mortality and morbidity in all countries of the world. Its pathogenetic aspect is characterized by progressive irreversible airflow limitation. However, the disease is also a chronic inflammatory disease of the bronchopulmonary tissue with systemic consequences [1]. .....
View PDF View FulltextPancreatic Metastasis from Unresectable Lung Adenocarcinoma: A Case Report
Metastatic lesions of the pancreas are uncommon, accounting for approximately 2% of pancreatic malignancies. The most common.....
View PDF View FulltextMesenteric Vein Thrombosis with Multiple Etiologies- A Rare Cause of Abdominal Pain During COVID Times
Acute mesenteric venous thrombosis is an uncommon cause of abdominal pain but can be potentially fatal if not diagnosed and treated early. We report an interesting case of ....
View PDF View FulltextMacular Hole Related Retinal Detachment in a Case with Myelinated Retinal Nerve Fiber Layers
Myelinated Retinal Nerve Fiber Layers (MRNFL) are retinal nerve fibers with a myelin sheath. This relative rare condition is usually benign without specific symptoms,.....
View PDF View FulltextGuillain Barre Syndrome & Covid-19: A Case Report
Besides respiratory symptoms, coronavirus disease 2019 (COVID-19), like the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), has neurological signs. Symptoms.....
View PDF View FulltextPost - Traumatic Stress Disorder (Ptsd) In Patients with Covid 19
Post-Traumatic Stress Disorder (PTSD) refers to situations in which traumatic experiences are caused by a person being exposed to emergencies outside of their daily life.....
View PDF View Fulltext‘Get The Patient in a Good Light’: The Role of the Physical Examination in Modern Medical Practice
[There is] a growing perception that the traditional bedside assessment is of increasingly limited value in modern medical practice......
View PDF View FulltextMolecular Signature and Anatomical Features of a Hypertrophic Scar From Abdominal Skin of a 36-Year-Old Female
Hypertrophic scarring is formed as a result of abnormal wound healing. Efforts have been made to understand the mechanism of hypertrophic scarring.....
View PDF View FulltextA Rare Translocation of t (1, 5) (q21, q32) in a Case of Myeloid Neoplasm With Eosinophilia
Myeloid neoplasm with eosinophilia is a kind of unusual hematological malignancy. Back in the morphological diagnosis era, the prognosis was.....
View PDF View FulltextClear Cell Renal Carcinoma with Focal Osseous Metaplasia: A Case Report and Review of the Literature
Osseous metaplasia in clear cell renal carcinoma (RCC) is uncommon with few cases reported. We present a case of a 66year-old male in which....
View PDF View FulltextFrom Simple Painkiller to an TNF-Alpha Inhibitor and Back Again or Doing Less is Always More in Geriatrics
81 y old male in LTCF with primary learning disability and cervico-dorso-lombarthrosis treated by WHO level 1 painkiller.....
View PDF View Fulltext“Double X” Cross Fixationin Paediatric Supracondylar Humerus Fractures: A 20-Year Expertise and 94 Surgical Interventions
Over the last 50 years, the developments emerged in the diagnosis and treatment of supracondylar humerus fractures (SHF) have significantly reduced the number of severe complications while.....
View PDF View FulltextRetesting Conjecture of Traditional Chinese Medicine Theory
This article proposes the following hypothesis based on studies from various aspects and various historical periods: meridians and collaterals are.....
View PDF View FulltextSuccessfully Treated New-Onset Pilocytic Astrocytoma in a Pregnant Patient
Pilocytic astrocytomas are typically pediatric brain tumors, and they are rarely diagnosed in older adults, especially in childbearing patients. However, if they present in pregnant women, they have a potentially catastrophic maternal and fetal outcome......
View PDF View FulltextGastrointestinal Symptoms in Patients with Coronavirus Disease 2019: A Single-Center Observational Study
The first case of novel coronavirus 2019 (COVID-19) was reported in Wuhan, China in December 2019, and the disease has rapidly.....
View PDF View FulltextGenital Hear Tourniquet Syndrome in A 5-Year Old Girl
A swollen and painful clitoris was noticed by the parents of a 5 year-old-girl. A hair tourniquet was found at the base of the clitoris and mechanically.....
View PDF View FulltextThe Differences Between Exfoliative Cheilitis and Factitial Cheilitis, Also Its Association with B12 Deficiency: A Review Article
Cheilitis is generally an inflammation that occurs in the vermillion border of the lips. Exfoliative Cheilitis is a chronic disease that occurs locally only on the vermillion border of the lips, which until .....
View PDF View FulltextCondyloma Acuminata in an Infant: Case Report in a Resource Limited Setting
Condyloma acuminata are soft, skin colored, fleshy warts that are caused by the Human Papilloma Virus (HPV), typically HPV 6 and 11 genotypes. .....
View PDF View FulltextPoncet’s Disease - A Commonly Missed Diagnosis
One of the rare presentations of both active pulmonary and extrapulmonary tuberculosis is polyarthropathy in the form of involvement.....
View PDF View Fulltext“Covid-19 A New Viral Trigger to Hemophagocytic Lymphohistiocytosis?”
We report a case of patient with COVID-19 pneumonia who had prolong course in critical care unit and developed clinical and laboratory features of Hemophagocytic Lymphohistiocystosis (HLH) supported by.....
View PDF View FulltextSafety and Efficacy of Modified BRTO-Assisted Endoscopic Cyanoacrylate Injection for the Treatment of Isolated Gastric Varices with Gastro-Renal Shunt
Ectopic embolization is the most serious complication of gastric variceal Cyanoacrylate injection for the treatment of isolated gastric varices (IGV) with gastro-renal shunt (GRS). To evaluate the safety and efficacy of modified balloon-occluded retrograde transvenous obliteration-assisted endoscopic Cyanoacrylate injection (E-BRTO) for the treatment of IGV with GRS......
View PDF View FulltextThe Role of Genetic Mutations in Y Chromosome Infertility Syndrome
Sex chromosome Y infertility is a genetic disorder that affects sperm production and causes affected men to become infertile. Most men with Y chromosome infertility .....
View PDF View FulltextSri Lankan Undergraduate Healthcare Student’s Perceptions of Interprofessional Learning: A Cross-Sectional Study
Interprofessional learning primarily aims to reduce prejudice among professionals, improve awareness of the roles and duties of other professional groups, and advance teamwork and collaborative competencies. This study was.....
View PDF View FulltextSustained Amylasemia in a Patient with Newly Diagnosed Alcoholic Cirrhosis; “A Clinical Picture That Is Worth a Thousand Words”.
Inflammation and distortion of the liver parenchyma leading to cirrhosis can be triggered by various causes. Alcohol is one of the commonest culprit factors among viruses, medications, toxic metals or autoimmune mechanisms.....
View PDF View FulltextIntradural Langerhans' Cell Histiocytosis Invading Frontal Bone of Skull: A Case Report with A Brief Review
In Langerhans Cell Histocytosis (LCH), there is a slow and abnormal proliferation of histiocytes. It is also called as Eosinophilic granuloma.....
View PDF View FulltextMucocutaneous Involvement in Behcets Disease
Behçet's disease is a chronic inflammatory disease characterized by its clinical polymorphism associating mucocutaneous involvement to systemic manifestations. .....
View PDF View FulltextThoracic Spinal Epidural Hematoma
An 8 year old male presented to the emergency department with back pain. The pain was non-radiating, located in the midthoracic region, progressively.....
View PDF View FulltextPseudo-Abdominal Hernia: A Retrospective Study with A Review of The Literature
Pseudo-abdominal hernia presents as a localized compressible bulge without an actual paresis of muscles. Pseudo hernias can occur after ventral nerve root damage secondary to excision of radiculopathy, .....
View PDF View FulltextFemale Emotional Processing: Hydrogen Peroxide & Alzheimer’s Disease
This paper continues the authors investigation into AD. We find that hydrogen peroxide appears to be the culprit in attacking the Papez circuit, especially in women. Familiarity with AT Math is assumed....
View PDF View FulltextStuttering
This paper provides some simple calculations from AT Math and Physics on how stuttering may occur. We see that adrenaline affects the frequency of the human mind resulting in a nerve signal velocity that is too slow for the tongue muscle to respond, thus no clear speech.....
View PDF View FulltextHydrogen Peroxide: Possible Cause of Amyotrophic Lateral Sclerosis (ALS)
This paper is about the possible cause for some types of ALS. The culprit once again is hydrogen peroxide. The chemical equations for the neurotransmitters involved yield an imbalance toward Ach which can be inhibitory. It is the inhibitory signal that stalls muscle s causing ALS.....
View PDF View FulltextChronic Covid -19 -The Never-Ending Virus
In this brief paper, we consider one case of the Covi-19 virus. The virus was contracted in December 2019 and has flared up about 15 times since then.....
View PDF View FulltextOne Cause of Alzheimer’s Disease: Gonorrhea and HSV-1
In this paper we show that a portion (1/10) of Alzheimer’s Disease patients have as a combination of Gonorrhea, HSV-1, and Neonatal Conjunctivitis. In previous papers, I suggested that AD is caused by either Gonorrhea or HSV-1.....
View PDF View FulltextEosinophilic Enterocolitis: A Rare Nosological Entity
Eosinophilic enterocolitis is an exceptionally rare disease with few cases described in the literature. It is the least frequent manifestation of the broad spectrum of gastrointestinal eosinophilic diseases. We describe.....
View PDF View FulltextGiant Portal Vein Aneurysm Incidetaloma
A 40-year-old woman referred by gynecologist. An abdominal ultrasound in the annual revision, a cystic mass in the hepatic hilum was detected. The patient did not present any symptoms, analytical without any alterations, and she did not have a personal history of liver disease on the clinical examination.....
View PDF View FulltextSpontaneous Epidural Hematoma and Cephalohematomas in Sickle Cell Disease
Spontaneous epidural hematoma and cephalohematoma are rare complications of sickle cell disease. Although several mechanisms have been proposed, these have most frequently been described in association.....
View PDF View FulltextMassive Lower Gastrointestinal Bleeding Due to Small Bowel Gastrointestinal Stromal Tumour (GIST)
Gastrointestinal Stromal Tumours (GIST) are rare, upper gastrointestinal bleeding is the most common clinical manifestation of GISTs, manifesting as hematemesis or melena. We are describing an acute surgical gastrointestinal bleeding that affecting patient stability secondary to GIST......
View PDF View FulltextManagement of Gastric Varices with BRTO Assisted Endoscopic High-Dose Histoacryl Injection: A Case Report and Review
Gastric varices is one of the most serious complication of portal hypertension. Endoscopic injection therapy with Histoacryl is the preferred method in managing gastric variceal bleeding. Iatrogenic ectopic embolism is the most serious complication associated with.....
View PDF View FulltextFamilial Mediterranean Fever Complicated by Henoch-Schönlein Purpura and Polyarteritis Nodosa in an Adult: A Case Report
Familial Mediterranean Fever (FMF) is the most frequent hereditary auto-inflammatory disease due to a mutation of the MEFV (Mediterranean fever) gene and belongs to the monogenic periodic fever syndromes. Familial Mediterranean fever has a particular ethnic distribution around the Mediterranean.....
View PDF View FulltextEarly Cervical Cancer Recurred with Uterine Fundus Metastasis After Laparoscopic Fertility-Sparing Surgery: A Case Report
Recently, the safety of minimally invasive radical hysterectomy for cervical cancer caused widespread controversy. However, the safety of minimally invasive fertility-sparing surgery for early stage cervical cancer is still uncertain......
View PDF View FulltextSpecialty Gown for Mastectomy Patients Designed to Improve Drainage System Management, Patient Experience
According to the Academy of Plastic Surgeons, there were over 493,000 breast plastic surgeries performed in 2019 across the United States [2]. Additionally, an estimated 268,600 new cases of invasive breast cancer will be diagnosed among women in 2019 [1]. Additionally, the American Cancer Society. Barring significant changes in this field, women will continue to need surgical gowns. The Papilla gown can provide a greatly improved post-surgery experience......
View PDF View FulltextAcute Gastrointestinal Bleed Due to Leiomyoma of the Ileum: A Case Report
Leiomyomas are benign smooth muscle tumours that may occur along the entire gastrointestinal tract. Usually occur in the small intestine. Bleeding is the most common symptom. Nausea, vomiting and abdominal pain are rarely present.....
View PDF View FulltextEstimation of Serum Copper and Zinc Levels Among Tuberculosis Patients in Khartoum State
Trace elements play an important role in tuberculosis infection because their deficiencies can be associated with impaired immunity. The aim to assessment the serum copper and zinc levels among the tuberculosis patients in Khartoum state...
View PDF View FulltextImproved Surgical Treatment for Craniostenosis in Children
To analyze the craniostenosis and the characteristics of development of cranial bones in children, introduce an improved surgical treatment for craniostenosis, and evaluate its efficacy and feasibility. Three children...
View PDF View FulltextConstitutional Symptoms Masking COVID-19 In A Patient with Primary Myelofibrosis
Constitutional symptoms of primary myelofibrosis can mask COVID-19 infection. We present the case of a patient...
View PDF View FulltextMicroabrasion Combined with Resin Infiltration to Treat a white Spot Lesion: A Clinical Case
Objective: Describe, with a case report, the treatment of a vestibular white spot lesion due to traumatic hypomineralization in a maxillary incisor, through the combined use of microabrasion and resin infiltration....
View PDF View FulltextChronic Natural Killer Cell Lymphoproliferative Disorders Treated with Interferon-Α: A Case Report
Chronic natural killer cell lymphoproliferative disorders are a hematological disorder which is characterized bythe proliferation ofCD3- cytotoxic natural killer cells. So far, the pathogenesis ofCLPDNK is still...
View PDF View FulltextDynamics of the COVID-19\\ Comparison between the Theoretical Predictions and the Real Data, and Predictions about Returning to Normal Life
A new coronavirus disease, called COVID-19, appeared in the Chinese region of Wuhan at the end of last year; since then the virus spread to other countries, including most of Europe. We propose a differentia...
View PDF View FulltextCOVID-19 and Responsible Conduct of Research
COVID-19 has emerged as one of the largest pandemic of century, with 15 785 641 confirmed cases of COVID-19,...
View PDF View FulltextEthics Review Preparedness During COVID-19 Outbreak and Local IRBs in Pakistan, The Forgotten Part
Current COVID-19 outbreak has shaken almost all aspects of health. Pakistan is lower middle income country where health system is fragmented due to chronic state of underinvestment in health. Provision of basic health...
View PDF View FulltextFactors Associated with the Duration of Viral Shedding and the Role of Lopinavir/Ritonavir in Patients with COVID-19
Coronavirus disease 2019 (COVID-19) causes severe community and nosocomial outbreaks; we aimed to ascertain the duration of viral shedding through repeated nasal swabs in patients with COVID-19 and factors associated...
View PDF View FulltextDrug Resistance, An Enemy of Targeted Cancer Therapies
The success of targeted cancer therapies will depend on the uniformity of the target cells. Cancer cells mutate and potentially can alter that target, defeating that therapy. A means of computing the number of altered...
View PDF View FulltextA Heterozygous Mutation M694V in the MEFV Gene and HLA-B27 Negative Spondyloarthritis: The Chicken Egg Paradox?
Ketamine is a drug with a long clinical history as an anesthetic and is approved by the US Food and Drug Administration (FDA) for that use. More recently, it’s been getting attention as a drug that may be of value in the treatment of depression, anxiety disorders, PTSD, OCD and other mood disorders [1-3]...
View PDF View FulltextPontocerebellar Hypoplasia: Literature Review and Clinical Study
Pontocerebellar Hypoplasia (PCH) refers to a group of rare, progressive, and hereditary neurodegenerative disorders with prenatal onset. Different subtypes have been identified based on the mutations present,...
View PDF View FulltextIntestinal Cystic Pneumatosis : Rare Case
Intestinal cystic pneumatosis is a rare condition characterized by the presence of gaseous cysts in the intestinal wall....
View PDF View FulltextBruises as First Manifestation of Cutaneous Angiosarcoma
Cutaneous angiosarcoma is a soft tissue sarcoma that presents as a violaceous plaque, resembling a persistent bruise on the head and neck. The hematoma-like lesions are pitfalls that could be the first spy of malignant vascular tumors....
View PDF View FulltextEarly Repair of Vesicovaginal Fistula
Vesicovaginal fistula is a common acquired fistula in obstetrics and gynecology. With the development of obstetric technology, the main cause of vesicovaginal fistula is benign gynecological operation....
View PDF View FulltextThe Diagnosis and Treatment of Robert's Uterus: A Case Report and Literature Review
Background: Robert's uterus is a very rare malformation and are associated with a severe dysmenorrhoea. It is rarely reported....
View PDF View FulltextMy Experience with Ketamine Therapy
Ketamine is a drug with a long clinical history as an anesthetic and is approved by the US Food and Drug Administration (FDA) for that use. More recently, it’s been getting attention as a drug that may be of value in the treatment of depression, anxiety disorders, PTSD, OCD and other mood disorders [1-3]...
View PDF View FulltextEumycotic Mycetoma (Madura’s Foot), Case Report and Literature Review
Madura foot is a rare disease in our country caused by chronic infections either bacterial or fungal organisms that involve skin and underlying soft-tissue of the foot, The diagnosis is made by clinical picture, microscopic..
View PDF View FulltextAorto-Esophageal Fistula and Metallic Stent
Esophageal metallic stents are indicated in the palliative treatment of malignant dysphagia [1]. The ones usually used are covered or partially covered. They have a low mortality rate directly associated (0.5-2%) [2]...
View PDF View FulltextAchondroplasia and Periodontal Disease - Molecular Testing Methods Case Report
Achondroplasia is an autosomal dominant genetic disease with its molecular mutation in gene encoding in type 3 of the receptor for fibroblast growth factor 3 (FGFR3). Although available literature describes..
View PDF View FulltextA Mild form of Familial Mediterranean Fever Associated with a Polymorphisms C.Nt 1588,-69G>
Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease caused by mutation(s) in the Mediterranean fever (MEFV, pyrinmarenostrin) gene. FMF is characterized by recurrent fever crisis combined..
View PDF View FulltextAbdominal Tumor Case Report
The ovarian teratoma is a tumor formed by pluripotent germina cells, benign or malign. In Surgical Clinic 1 there have been operated a lot of giant abdominal tumors...
View PDF View FulltextThe Developing Patterns of Calibrated Implant Stability Quotients of Posterior Implants
Many surgical protocols were modified to improve dental implant primary stability for the ensurance of implant success. However, the conclusions of applying osteotome condensation technique could..
View PDF View FulltextBilateral Ovarian Thecoma in a Postmenopausal Woman with Rapidly Progressed Severe Hyperandrogenism
Sex cord-stromal neoplasms of the ovary are an infrequent cause of androgen excess and virilization in women. We report a case of a 60 years old woman with rapidly progressive signs of virilization and indeterminate..
View PDF View FulltextAtypical Presentation of Acanthamoeba Keratitis- Case Report and Review of the Literature
The purpose is to present painless Acanthamoeba keratitis and to summarize actual literature data on this ocular infection. A 48-year-old women with a history of occasionally soft contact lens wear was referred to our hospital..
View PDF View FulltextAnesthetic Management of a Parturient with a History of Primary Spinal Malignant Melanoma
Background: Primary CNS malignant melanomas are quite rare as they account for 1% of all CNS tumors. The potential presence of spinal cord malignancies is worrisome when considering neuraxial techniques due to possible complications..
View PDF View FulltextSurgical Treatment for Iatrogenic Intrathoracic Subclavian Artery Aneurysm
Subclavian artery aneurysms (SAAs) are not common but with possible limb and life threatening complications...
View PDF View FulltextInfectious Aortitis Complicated by Type B Intramural Hematoma
An 83-year-old woman was admission due to intermittent fever for 1 week. Her temperature was 38.5°C, and chest X-ray demonstrated tortuosity of aorta with calcification of aortic arch. Her blood cultures subsequently all grew..
View PDF View FulltextHypopyon as an Unusual Complication of Varicella Infection in a Girl with Atopic Dermatitis
Varicella-Zoster-Virus (VZV) infection, also known as chickenpox, is a very common childhood affliction manifesting primarily on the skin. Typical skin lesions are small itchy single standing vesicles on..
View PDF View FulltextPortosystemic Shunt for Treatment of Symptomatic Varices in Polycythemia Vera Patient: A Case Report
Myeloproliferative disorders are commonly associated with portal vein thrombosis, which can lead to extensive and symptomatic,..
View PDF View FulltextIndazole Synthetic Cannabinoids Intoxication Associated with Fatal Cardiac Complications: Two Case Reports
Usage of synthetic cannabinoids is associated with severe medical consequences and limited detectability in toxicology panels...
View PDF View FulltextA Rare Case of Amyand’S Hernia with Acute Appendicitis
Amyand’s hernia is an extremely rare and atypical hernia that is difficult to diagnose clinically characterized by the herniation of the appendix into the inguinal sac. The reported incidence is less than 1% of all adult..
View PDF View FulltextHookah Use and COVID-19
A hookah (shisha, waterpipe) use may increase the risk of suffering from serious symptoms due to COVID-19. Like smoking, ..
View PDF View Fulltext007 (Opioid Oligopoly and the Seven Deadly Sins)
The most common market structure in today’s market place is the oligopoly. An argument can be made that the few pharmaceutical companies who market, manufacture, distribute opioids worldwide can be defined as an “opioid...
View PDF View FulltextToxin Positive Corynebacterium Diphtheriae Skin Ulcers in a Vaccinated Traveller
A 20 year old German volunteer presented in good general condition without fever to our outpatient department with cutaneous ulcers (Figure 1) on the lower limbs and swelling of the right lower leg. The patient had just returned from a one year stay in the Ivory Coast and mentioned several insect bites a week ago while still abroad...
View PDF View FulltextAngiosarcoma like Squamous Cell Carcinoma of the Oral Cavity— Report of Rare Subtype of Squamous Cell Carcinoma
Acantholytic Squamous Cell Carcinoma (SCC) of the oral cavity is an uncommon but well recognized variant of SCC and angiosarcoma like,..
View PDF View FulltextDramatic Improvement in Dyspnea in A Non-Small Cell Lung Cancer Patient, Following Administration of Anti-IL-6R
Currently in most Lung Cancer cases in which there is tumor progression, the molecular approach is to search for new mutations, usually utilizing circulating free DNA. There are however cases where a trauma, such as an operation..
View PDF View FulltextCongenital Non-Union of Olecranum: A Review of Literature
Congenital non-union of the olecranum was first described by Habbe in 1942. A few authors described this anomaly in a very young patients. Only Two authors publicated the treatment of patella cubiti. Here, I document a brief review of literature.In this review, there are not figures and outcomes,..
View PDF View FulltextNicolau Syndrome Due to Benzathine Penicillin Injection: (A Case Report)
Nicolau Syndrome(NS) is a rare complication of intramuscular injections, which is manifested by pain, edema, and livedoid discoloration of the skin immediately after injection. The pathophysiology of the disease is uncertain,..
View PDF View FulltextAssociation between Testosterone Levels and Clinical Markers of Atherosclerosis
To investigate the association between testosterone levels and parameters obtained from the clinical exercise stress test from 119 middle-aged Swedish men....
View PDF View FulltextAn Unusual Case of Nasopharyngial Adenoid Cystic Carcinoma with Intracranial and Orbital Extension: A Challenge for Innovative Conformal Radiotherapy Techniques
Adenoid cystic carcinoma of nasopharynx is rare. When tumor is resectable, surgery alone or followed by radiotherapy is frequently used for treatment. In the other hand, when tumor is not resectable...
View PDF View FulltextA Study of the Prediction of Bowel Resection Due to Strangulated Small Bowel Obstruction
In this retrospective study, we aimed to assess the predictive factors for bowel resection due to Strangulated Small Bowel Obstruction (SSBO).
View PDF View FulltextCan Lung Ultrasound in Patients with Fever of Unknown Origin Detect Early Signs of COVID-19 Pneumonia?
The increasing interest in Lung Ultrasound (LUS) over the last years led to a great diffusion and better experience in using this technique, which became an essential tool for clinicians. During the current Coronavirus Disease 2019
View PDF View FulltextSevere Recurrent Hyponatremia and Acute Renal Failure Due to Shapiro’s Syndrome
Shapiro syndrome is a rare disorder defined by the clinical trial of relapsing episodes of hypothermia, hyperhidrosis and agenesis of the corpus callosum.....
View PDF View FulltextSynchronous Lung Cancer with Bone Metastasis and Rectal Cancer: A Case Report
The incidence of synchronous lung cancer and colorectal cancer is very rare. Therefore, physicians might lead to misdiagnosis as colorectal cancer with lung metastasis when lung lesion is found in a patient with colorectal cancer
View PDF View FulltextPreliminary Results of Fecal Microbiota Transplantation in Diarrhea-Predominant Irritable Bowel Syndrome: Case Series on 12 Patients
Irritable Bowel Syndrome (IBS) is associated with intestinal dysbiosis and it has been suggested Fecal Microbiota Transplantation (FMT) has a positive effect on the condition. In this preliminary study, we recruited 12 IBS patients with moderate to severe diarrhea (IBS-D) and assessed the clinical outcomes of single FMT.
View PDF View FulltextPostpartum Meningitis by Enterococcus Faecalis Secondary to Neuraxial Anesthesia
Meningitis is an infrequent and serious cause of postpartum fever that requires early diagnosis and treatment to prevent serious complications and to reduce the high mortality rate. Neuraxial anesthesia is a frequently used technique
View PDF View FulltextAdvanced Esophagogastric Cancer after Bariatric Procedure
A 74-year-old man, non-smoker or alcoholic, underwent gastric bypass with stapled division of the stomach and Roux-en-Y gastrojejunostomy 20 years ago. A band was used to limit the emptying of the gastric pouch.
View PDF View FulltextHerpes Simplex Encephalitis in Medulloblastoma Patients: Case Report and Review of Literature
Encephalitis caused by Herpes Simplex Virus (HSV) and medulloblastoma are both fairly rare disorders with relatively poor prognoses. We experienced a case of HSV encephalitis (HSE) in which the patient presented 1 year after surgical resection and radiation therapy and 1 month after chemotherapy
View PDF View FulltextSuperior Mesenteric Artery Syndrome Treated by Laparoscopic Duodenojejunostomy
Superior Mesenteric Artery syndrome (SMA Sd) is a very rare disease. It is suspected in the case of intestinal obstruction in severely underweight patients. When conservative management fails surgery becomes needed, with laparoscopic duodenojejunostomy being the best approach........
View PDF View FulltextBilateral Anterior Glenohumeral Dislocation A Case Report and A Review of the Literature
The glenohumeral joint dislocation is the most common type of joint dislocation [1, 2]. Anterior dislocation has a higher incidence than posterior dislocation [3]. However, bilateral dislocation, either anterior or posterior, has r.......
View PDF View FulltextColopleural Fistula. A Case Report and Review of Literature
The presence of a colopleural fistula is a rare event related to several factors, inadequate placement of drains, poor surgical technique, infection or dehiscence of a GI anastomosis. Only a small percentage occurs as a complication of inflammatory bowel disease, cancer, trauma or radiation.......
View PDF View FulltextOnset of Graves’ Disease and Thyroid Cancer After Chemo and Radiotherapy for Medulloblastoma
1.1. Introduction: External beam Radiotherapy (RTE) treatment for head and neck cancers is associated to the development of late thyroid sequelae whose risk is persistent for decades. 1.2. Case report: We describe a rare case of a 21 yrs woman treated with RTE plus CHE for........
View PDF View FulltextAtypical Presentation of Post-Kala Azar Dermal Leishmaniasis in Bhutan
Background: Anti-PD-1 antibodies have activity across many cancers. Changes in the balance of the immune system may lead to some autoimmune manifestations, also referred to as immune-related adverse events (IRAEs). These adverse events were described affecting different systems of the body, including the endocrine system........
View PDF View FulltextCheckpoint Inhibitor Associated Autoimmune Diabetes and Hashimoto's Thyroiditis
Background: Anti-PD-1 antibodies have activity across many cancers. Changes in the balance of the immune system may lead to some autoimmune manifestations, also referred to as immune-related adverse events (IRAEs). These adverse events were described affecting different systems of the body, including the endocrine system........
View PDF View FulltextThe Association of Left Atrial Enlargement in DifferentSubtypesof Ischemic Stroke Basedon Toast Classification
subtypeofeachpatientwasdeterminedbasedTOASTcriteria.PwavemorphologyinleadV1ofECG wasevaluatedineachpatienttolookforleftatrialenlargementandPTFV1>4,000microvoltmswas considered to be left atrial enlargement by ECG voltage criteria.......
View PDF View FulltextMalignant Pheochromocy tomawith Brain Abscess Induced by Nocardia Infection after Treatment with Cyclophosphamide (CVD), 5-Fluorouracil(FU) and Carboplatin (CBDCA)
A 47 years old man who had been diagnosed as malignant pheochromocytoma with metastases of lumbar spines at 21 years old. He had received partial tumor abscission, radiotherapy and 131I-MIBG treatment, He had been suffered from gait disturbance for spinal compression by the metastasis of verteb......
View PDF View FulltextEffects of Fistulojejunostomy in Treatment of Pancreatic External Fistula
Conclusions: Fistulae-jejunum Roux-en-Y anastomosis is an easy, safe and reliable method totreat pancreatic external fistula, which preserves pancreatic exocrine and endocrine function, the recommending surgery within 3 to 6 months after onset of pancreatic external fistula......
View PDF View FulltextIntravenous & Endocavitary Contrast Enhanced Ultrasound(CEUS) in Multiseptated Pyogenic Liver Abscess Drainage
Pyogenic liver abscess is a potentially life-threatening pathology, while image-guided drainage is highly indicative as first-line treatment approach. We report the case of an 84-year-old woman, diagnosed with large multiseptated pyogenic liver abscess, aiming to stress out the immense contribution of both intravenous and endocavitary administration of Sonovue ™ (Bracco-Milan) in US-guided percutaneous interventional procedures.....
View PDF View FulltextResting Energy Expenditurein Anorexia Nervosa: A Case Report in Two Monozygotic Twins
Introduction:Littleisknownaboutrestingenergyexpenditure(REE)inpatientswithanorexia nervosa(AN)duringrefeedingandafterrecovery,duetothemetabolic,bodycompositionandphy - sical activity changes.....
View PDF View FulltextTwo Cases of Suspected Novel Coronavirus Pneumonia Treated by Pidotimod Dispersible Tablets
The global spread of novel coronavirus pneumonia (COVID-19) directly endangers social health and safety.....
View PDF View FulltextSome Suggestion son the Treatment of Covid-19 Pneumonia
Dear friends, as Chinese doctor, I have some suggestions to your anti-epidemic situation on the Covid-19. 1. Pulmonary lavage may be the most effective treatment for the patients. As you know, the pathological changes in the patient’s lungswere that a largeamount of effusion was gatheredinperipheral bronchioleandformedintothicksputumwhichcouldnotbesuckedouteasily.Wecanseethewhite lungsinthesepatients’thoracicCTforthereasonoftheeffusion.Notonlythethicksputumcanlead to respiratory.....
View PDF View FulltextLaparoscopic Cholecystectomy for a Patient with Double Gallbladder Duct: A Case Report
Introduction: Duplicated cystic ducts with a single gallbladder are extremely rare. We summarize and analyze the diagnose and treatment process of one case of gallstone disease in a patient with doublecystic.....
View PDF View FulltextBreast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) - Case Report
Demand for aesthetic breast surgery is increasing worldwide, both for cosmetic reasons and postoperative breast reconstruction for breast cancer patients. Although the number of women with breast prostheses is....
View PDF View FulltextCT Diagnosis of Rare Case of Morgagni Hernia in an Adult
Introduction: Morgagni’s hernia is the rarest of the congenital diaphragmatic defects with a reported frequency of 1% to 5.1% Morgagni hernias are more commonly seen on the right side and it occurs more commonly in females. However, most patients remain asymptomatic and the majority of.....
View PDF View FulltextCutaneous Larva Migrans: ACase Report in aTraveler Child
Cutaneous Larva Migrans (CLM) is the most common skin disease of tropical origincaused by hookworms larvae, occurring in international travelers. .....
View PDF View FulltextStatistical Analysis on COVID-19
1.1. Background: Since receiving unexplained pneumonia patients at the Jinyintan Hospital in Wuhan, China in December 2019, the new coronavirus (COVID-19) has rapidly spread in Wuhan, China and spread to the entire China and some neighboring countries. We establish the dynamics model of infectious diseases and time series model to predict the trend and short-term prediction of the transmission of COVID-19, which will be conducive to the intervention and prevention of COVID-19 by departments.....
View PDF View FulltextPigmented Fungi Form Papilla of The Tongue – A Rare Entity
Crohn’s Disease (CD) is a main kind of Inflammatory Bowel Disease (IBD) whose etiology is unclear but complex and the effective treatment is deficient. Since Tumor Necrosis Factor (TNF) inhibitor used to treat CD, greatly improvement has been seen in patients’ clinical symptom and living condition. However,....
View PDF View FulltextDexmedetomidineor Clonidine: Anesthetist’s Choicein Laparo- scopic Gynecological Surgeries
Laparoscopic surgeries have revolutionized surgicaldomains. It involves in flationofabdomen with carbondioxide(CO2)whichaltershemodynamicandmetabolicparameters.Thisrandomizedprospective study was conducted in the department of Anesthesiology, tertiary care government hospital on 48.....
View PDF View FulltextA A Pulmonary Noncaseating Granuloma Associated with InfliximabinCrohn’s Disease:The First Case Reported in China
Crohn’sDisease(CD)isa mainkindofInflammatoryBowel Disease(IBD) whoseetiologyis un- clear butcomplexand the effective treatmentisdeficient. Since TumorNecrosisFactor (TNF) inhibitorusedt.....
View PDF View FulltextA Case Report of Acute Lymphoblastic Leukemia Patient Cured By Homeopathy
Leukemia (ALL) is a cancer of lymphoid line of blood cells characterized by pallor complexion, progressive fatigue, easybruising and bleeding, enlarged lymph nodes with bone pains. Incidents of ALL are growing globally with fatal results[1]. A demographic report.....
View PDF View FulltextLymphedema Complications to Prophylactic Subcutaneous Nipple- Sparing Mastectomy and Breast Augumentation with an Implant
A 42 year old woman with three children had a hereditary increased risk for breast cancer. She wanted a prophylactic subcutaneous nipple- sparing mastectomy combined with mastopexi and breast augmentation all in one operation.. .....
View PDF View FulltextOral Terbinafine Plus Systemic Glucantime Vs. Systemic Glucantime Alone in The Treatment of Cutaneous Leishmaniasis
Cutaneous Leishmaniasis(CL) as an endemic disease is a major health problem in Isfahan, a large province in Iran. To date, pentavalentantimonials are the first line treatment in all types of leishmaniasis [1]. However, their cost, side effects and the problem with injection route, necessitate further study......
View PDF View FulltextBilateral Varus Deformity Correctionand LegLengthening with an Ilizarov Fixatorina Femalewith Trichorhinophalangea l SyndromeType1(TRPSI)–CaseReport
Trichorhinophalangeal Syndrome Type I (TRPS I) is a rare multisystem disorder with autosomal dominantpatternofinheritance.ThedisorderwasfirstdescribedbyA.Giedionin1966[1].Patients with TRPS.... View PDF View FulltextFetal Vascular Rings: Beyond The Anomalies of The Aortic Arch
Different anomalies related to the inappropriate development of the ductus arteriosus or the aortic arch have been described, in some cases accompanied with chromosomal or morphological anomalies, and also being able to form a vascular ring that can compromise the postnata ..... View PDF View FulltextPulmonary Noncaseating Granuloma Associated with Infliximabin Crohn’s Disease: The First Case Reported in China
Crohn’s Disease (CD) is a main kind of Inflammatory Bowel Disease (IBD) whose etiology is unclear but complex and the effective treatment is deficient. Since Tumor Necrosis Factor (TNF) inhibitor......
View PDF View FulltextPatient with Hypertrophic Cardiomyopathy Combined and Atrioventricular Conduction Disturbance
53 years old Caucasian male patient with suspected aortic valve stenos is and coexisting left ventricle wall hypertrophy was referred to clinical department of interventional cardiology aiming cardio....
View PDF View FulltextPigmented Fungi Form Papilla of The Tongue – A Rare Entity
Case Report: We describe a case report of 20 years old female with pigmentation over the dorsum of the tongue since childhood. Examination of the oral cavity showed pigmentation of fungiform papilla on lateral and dorsal aspect of tongue. .....
View PDF View FulltextA Case Report of Acute Lymphoblastic Leukemia Patient Cured By Homeopathy
Background: Acute Lymphoblastic Leukemia (ALL) is a cancer of lymphoid line of blood cells character-ized by pallor complexion, progressive fatigue, easy bruising and bleeding, enlarged lymph nodes with bone pains. Incidents of ALL are growing globally with fatal results [1]. A demographic report p.....
View PDF View FulltextA Dexmedetomidine or Clonidine: Anesthetist’s Choice in Laparoscopic Gynecological Surgeries
Laparoscopic surgeries have revolutionized surgical domains. It involves inflation of abdomen with carbon dioxide (CO2) which alters hemodynamic and metabolic parameters. This randomized prospective study was conducted in the department of Anesthesiology, tertiary care government hospital on 48 patients undergoing diagnostic.....
View PDF View FulltextSystemic Sclerosis Associated with Occupational Exposure to Solvents
:Systemic Sclerosis (SS) isarare multisystemicd is order with changesin the immunesystem, vascular and connective tissue. Furthermore, there is an increase in the synthesis and accumulation of collagen .....
View PDF View FulltextIntraosseous Access Under Adverse Circumstances
This presentation displays the case of a 5-year old child suffering from severe pneumonia. No antimicrobial drugs had been given in the pre hospital setting so far. The boy lived in a remote home caring for children with innate, severely disabling musculoskeletal disorders. The rescue services were called in the morning due to the apparently life-threatening condition of the patient. In order to cover the medical emergency......
View PDF View FulltextSubconjunctival Bleeding As Uncommon First Hemorrhagic Sign in Patient with Acquired A Haemophilia
Acquired A haemophilia (AHA) is a rare disease resulting from autoantibodies (inhibitors) against coagulation factor VIII that leads to bleeding. It occurs mostly in elderly but can be associated with pregnancy and autoimmune disease in youngsters (1), about 50% of cases are considered idiopathic.....
View PDF View FulltextAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
The incidence of renal cell carcinoma (RCC) in patients with polycystic kidney disease (PCKD) has shown to be higher compared to the general population [1, 4]. However the incidence of RCC in young individuals (.....
View PDF View FulltextUnderstanding Anchorage in Orthodontics-A Review Article
Beforestartingactivetreatmentofanyorthodonticcase,anchoragemustbeplannedwellto get rid of the problems that might accompanied the treatment procedures. This article reviewedtheanchoragefromallaspectsstartingfromthedefinition,sources,types,planning, anchorage loss and how to avoid it.d......
View PDF View FulltextMental State Alterations and Transient Bradypnea Resulting from Pneumocephalus After the Application of Epidural Anesthesia: A Case Report
Pneumocephalus is a very rare complication after the application of epidural anesthesia. Pneumocephalus can cause headache, convulsions, altered state of consciousness, and hemodynamic instability.....
View PDF View FulltextAnalysis on the Treatment of Colorectal Cancer
Over the past few years, Robotic surgery has been an emerging field in colorectal surgery. Over years there has been continuous shift towards minimally invasive procedures with enormous p .....
View PDF View FulltextKeratin 5 Mutation in a Bulgarian Family with Dowling - Degos Disease – A Case Report and a Review of the Literature
Dowling-Degos Disease (DDD) is a rare reticular pigmentary disorder with an autosomal dominant inheritance. Morbus Galli-Galli is considered to be an acantholytic variant of the disease. Mutations in keratin 5 gene (KRT5) have been found in the majority of DDD patients. Herein, the first Bulgarian pedigree .....
View PDF View FulltextA Serious Case of Vitamin B12 Deficiency Steroids
This Report Illustrates the Catastrofic Damage to the Sensory System if the Diagnosis of Vitamin B12 Deficiency osnot done on Time to Reverse the Syntoms and Signs of Such Clinical Case. The Patient (Vdr), a Male of 70-Year-Old Started with Lack of Control by the Hands of Relatively Light Objects without Pain or other Signs of Damage to the Upper Extremities or Syntoms in the Lower Ones......
View PDF View FulltextTo Find Out the Causes of Extraction of Teeth in the Patients Coming to the Department of Oral and Maxillofacial Surgery at Kantipur Dental College Teaching Hospital and Research Center from January 2014 to December 2018
The main objective of this study is to find out the reasons for the extraction of the teeth on patients visiting to the Department of oral and maxillofacial surgery at Kantipur Dental College Teaching Hospital and Research.....
View PDF View FulltextTotally Extra-Peritoneal (TEP) Laparoscopic Ventral Hernia and Incisional Hernia Repair: Reverse TEP(R-TEP)
Laparoscopic ventral hernia and incisional hernia repair has now become a standard technique. However, the disadvantage of this technique is the contact between the mesh and tacks and the viscera. T......
View PDF View FulltextModern Military Neurotrauma and its Complications in War Conditions in megalopolis Thromboembolectomy
This work contains information about military neurosurgical traumas with their complications. Here will be spoken about neurosurgical medical treatment in the present military actions (local military.....
View PDF View FulltextAn Unusual and Interesting Case of Coronary Cameral Fistula
(NFI) Coronary cameral fistula is a sizeable communication between a coronary artery, bypassing the myocardial capillary bed a.. .....
View PDF View FulltextPlasma Cell Granuloma of the Clavicle- A Rare Case Presentation
Plasma cell granuloma (PCG), also known as inflammatory pseudotumor, is a rare non neoplastic lesion. Although the etiology of the lesion is unclear, an altered antigen antibodyreaction have been implicated to play a role.......
View PDF View FulltextPreventive Effect and Safety of Pregabalin for FOLFOX-Related Peripheral Neurotoxicity in Patients with Advanced and Recurrent Colorectal Cancer: The Perpetual Study Estimated by United Sections in Gifu for Colorectal Cancer (Perseus CRC-01 Study)
In patients with colorectal cancer, peripheral nerve symptoms as an adverse effect of oxaliplatin (L-OHP) can result in dose restrictions of L-OHP. Presently, there is no effective cure for the peripheral neuropathy caused by L-OHP. The objective of this study was to investigate the effect of PGN in unresectable and metastatic colorectal cancer patients with peripheral neuropathy. Target patients were those receiving L-OHP preparations FOLFOX6 or FOLFOX7 administered to treat unresec......
View PDF View FulltextContralateral Extremity Paresis and Numbness Caused by Pos-tero lateral Disc Herniation at C3–C4 in a Teenager
We report a rare case of a teenager presenting with progressive contralateral extremity paresis and numbness caused by posterolateral disc herniation at C3-C4. Intervertebral decompression and artificial disc replacement was performed. Follow-up at 2 months showed complete neurologic.....
View PDF View FulltextParallel Lives: A Case Series of Three Boys with Persistent Reactive Attachment Disorder
Reactive Attachment Disorder (RAD), only diagnosed in the context of early abuse and neglect, is characterised by failure to seek and accept comfort. It involves lack of activation of the - developmentally essential - .....
View PDF View FulltextMultiple unilateral submandibular duct calculi: A case report
Salivary gland calculi account for the most common disease of the salivary glands. The majority of sialoliths occur in the submandibular gland or its duct and are a common cause of acute and chronic infections. Sialolith can be unilateral, bilateral, single or multiple. Depending on the gland affected and stone location, there are various methods available for the management of salivary.....
View PDF View FulltextA New Diagnosis of Myasthenia Gravis in Frailty Patient Affected by Chronic Obstructive Pulmonary Disease Treated With Steroids
In July 2017 we observed, in our Internal Medicine Department, the patient F.A. recently affected by recurrent Chronic Obstructive Pulmonary disease (COPD). Anamnesis’ data have underlined the presence of Permanent Atria Fibrillation (FAP) and severe carotid stenosis, treated with carotid.....
View PDF View FulltextLiving longer and living better
It was with great enthusiasm that we have seen the results published by Francis et al. concerning the adjuvant hormone therapy. In the SOFT study, the 8 year disease-free survival rate was 78.9% in patients who did only tamoxifen,.....
View PDF View FulltextCT-Guided Marking of A Small Abdom in alWall Metastasis of Chromo phobeRenal Cell Carcinoma
WedescribeafemalepatientinwhomCT-guidedhookwiremarkingenabledaneasyandmini- mally invasive removal of a small abdominal wall metastasis of chromophobe renal cell carci- noma despite obesity and scars after repeat laparotomies......
View PDF View FulltextAcute Upper Arm Ischemia in a Patient with Human Immunodeficeincy Virus Infection: Underwent Successful Surgical Thromboembolectomy
Patients with human immunodeficiency virus (HIV) are in hypercoagulabe state due to various coagulation abnormalities and at increased risk for thromboembolic events. We report acute upper arm ischemia.....
View PDF View FulltextRefractory Hypertension Dueto Pheochromocy to main A Type IN eutro fibromatosis:Single Case Report
(NFI) is a common genodermatosis, with an incidenceof1newcaseto3000-3500livebirths.Describedin1882,itoccursfromgenemutations of the encoding protein called neurofibrinin. NF1 patients are at increased risk for neoplasms. Aims:Wereportacaseofapatientwithneurofibromatosiswitharecentdiagnosisofpheochro2. Keywords Mesh terms; Neurofibromatosis type1;Hypertension;Pheochromocytoma mocytoma(PHEO),duetotherarityofthisassociation.1.2.CaseReport:Fourty-sexyearsold femalepatientwithNF1andhypertensionsincetheageof25,developingdifficultyincontrol- ling blood pressure levels. .....
View PDF View FulltextImage is Hearts in The Large Bowel
Biopsy of colon in a case of ulcerative recto-colitis stained with hematoxylin and eosin method showing a dilated colonic gland with the heart shape located near to a second more irregular, symmetric gland, as if this is an image reflected in a pond......
View PDF View FulltextCo-Existence of Synodontia & Talon Cusp in Mandible: A Rare
The aim of reporting this case is to bring to light a different kind of tooth developmen-tal anomaly very rarely reported in literature......
View PDF View FulltextPrenatal Diagnosis of Denys-Drash Syndrome
Denys-Drash syndrome consists of the triad of progressive nephropathy characterised by diffuse mesangial sclerosis (DMS), genital abnormalities, and Wilms tumour. Nephropathy may range from early onset proteinuria to nephrotic syndrome to end stage renal failure. Genital malformations affects both external and internal genitalia. It may range from penoscrotal hypospadias, bilateral cryptorchidism to an enlarged clitoris with fused labia and a urogenital sinus to atrophic uterusto streak ovaries or dysgenetic testes. The risk of developing Wilms’ tumor may be as high as 50%......
View PDF View FulltextA Novel Approach to Treat Postoperative Nausea and Vomiting (PONV) After General Anesthesia
Postoperative nausea and vomiting (PONV) is an everyday problem in each recovery room [1]. The use of total intravenous anesthesia (TIVA) and the administration of dexamthasone and ondansetron helps to significantly reduce the incidence of PONV [2]. However, very few patients suffer from PONV despite of these measures. They seem to be resistant to any kind of treatment after the onset of nausea and/or vomiting.....
View PDF View FulltextImpactions in Orthodontics - A Review
Tooth eruption involves the migration of the teeth from a nonfunctional position within the bone to a functional position in the jaw. In orthodontic practice, it is inevitable that one will encounter eruptive abnormalities s.....
View PDF View FulltextSuccessful Treatment of Systemic Sarcoidosis with Tranilast
Although the effectiveness of tranilast in cutaneous sarcoidosis has been reported, its recorded adoption in systemic sarcoidosis is finite. We report a case of huge subcutaneous sarcoidosis withmultipleorganinvolvementandsystemicsymptomsrelievedquicklyafterthetreatmentof tranilast, suggesting that tranilast is expected to become the first-line therapy of sarcoidosis as for its less side effect......
View PDF View FulltextRecurrent Swelling of the Lower Limbs (Lymphedema) As a Manifestation of the Idiopathic Hypereosinophilic Syndrome
Hypereosinophilic syndrome is an unexplained disorder characterized by prominent blood and bone marrow eosinophilia and tissue eosinophil infiltration. It can cause damage/dysfunction of multiple organs, mainly involving the skin, heart, lungs, gastrointestinal tract and the nervous system.....
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