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Volume 4 Articles

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Volume 4 Articles

Estimation of Serum Copper and Zinc Levels Among Tuberculosis Patients in Khartoum State

Trace elements play an important role in tuberculosis infection because their deficiencies can be associated with impaired immunity. The aim to assessment the serum copper and zinc levels among the tuberculosis patients in Khartoum state...

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Improved Surgical Treatment for Craniostenosis in Children

To analyze the craniostenosis and the characteristics of development of cranial bones in children, introduce an improved surgical treatment for craniostenosis, and evaluate its efficacy and feasibility. Three children...

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Constitutional Symptoms Masking COVID-19 In A Patient with Primary Myelofibrosis

Constitutional symptoms of primary myelofibrosis can mask COVID-19 infection. We present the case of a patient...

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Microabrasion Combined with Resin Infiltration to Treat a white Spot Lesion: A Clinical Case

Objective: Describe, with a case report, the treatment of a vestibular white spot lesion due to traumatic hypomineralization in a maxillary incisor, through the combined use of microabrasion and resin infiltration....

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Chronic Natural Killer Cell Lymphoproliferative Disorders Treated with Interferon-Α: A Case Report

Chronic natural killer cell lymphoproliferative disorders are a hematological disorder which is characterized bythe proliferation ofCD3- cytotoxic natural killer cells. So far, the pathogenesis ofCLPDNK is still...

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Dynamics of the COVID-19\\ Comparison between the Theoretical Predictions and the Real Data, and Predictions about Returning to Normal Life

A new coronavirus disease, called COVID-19, appeared in the Chinese region of Wuhan at the end of last year; since then the virus spread to other countries, including most of Europe. We propose a differentia...

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COVID-19 and Responsible Conduct of Research

COVID-19 has emerged as one of the largest pandemic of century, with 15 785 641 confirmed cases of COVID-19,...

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Ethics Review Preparedness During COVID-19 Outbreak and Local IRBs in Pakistan, The Forgotten Part

Current COVID-19 outbreak has shaken almost all aspects of health. Pakistan is lower middle income country where health system is fragmented due to chronic state of underinvestment in health. Provision of basic health...

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Factors Associated with the Duration of Viral Shedding and the Role of Lopinavir/Ritonavir in Patients with COVID-19

Coronavirus disease 2019 (COVID-19) causes severe community and nosocomial outbreaks; we aimed to ascertain the duration of viral shedding through repeated nasal swabs in patients with COVID-19 and factors associated...

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Drug Resistance, An Enemy of Targeted Cancer Therapies

The success of targeted cancer therapies will depend on the uniformity of the target cells. Cancer cells mutate and potentially can alter that target, defeating that therapy. A means of computing the number of altered...

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A Heterozygous Mutation M694V in the MEFV Gene and HLA-B27 Negative Spondyloarthritis: The Chicken Egg Paradox?

Ketamine is a drug with a long clinical history as an anesthetic and is approved by the US Food and Drug Administration (FDA) for that use. More recently, it’s been getting attention as a drug that may be of value in the treatment of depression, anxiety disorders, PTSD, OCD and other mood disorders [1-3]...

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Pontocerebellar Hypoplasia: Literature Review and Clinical Study

Pontocerebellar Hypoplasia (PCH) refers to a group of rare, progressive, and hereditary neurodegenerative disorders with prenatal onset. Different subtypes have been identified based on the mutations present,...

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Intestinal Cystic Pneumatosis : Rare Case

Intestinal cystic pneumatosis is a rare condition characterized by the presence of gaseous cysts in the intestinal wall....

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Bruises as First Manifestation of Cutaneous Angiosarcoma

Cutaneous angiosarcoma is a soft tissue sarcoma that presents as a violaceous plaque, resembling a persistent bruise on the head and neck. The hematoma-like lesions are pitfalls that could be the first spy of malignant vascular tumors....

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Early Repair of Vesicovaginal Fistula

Vesicovaginal fistula is a common acquired fistula in obstetrics and gynecology. With the development of obstetric technology, the main cause of vesicovaginal fistula is benign gynecological operation....

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The Diagnosis and Treatment of Robert's Uterus: A Case Report and Literature Review

Background: Robert's uterus is a very rare malformation and are associated with a severe dysmenorrhoea. It is rarely reported....

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My Experience with Ketamine Therapy

Ketamine is a drug with a long clinical history as an anesthetic and is approved by the US Food and Drug Administration (FDA) for that use. More recently, it’s been getting attention as a drug that may be of value in the treatment of depression, anxiety disorders, PTSD, OCD and other mood disorders [1-3]...

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Eumycotic Mycetoma (Madura’s Foot), Case Report and Literature Review

Madura foot is a rare disease in our country caused by chronic infections either bacterial or fungal organisms that involve skin and underlying soft-tissue of the foot, The diagnosis is made by clinical picture, microscopic..

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Aorto-Esophageal Fistula and Metallic Stent

Esophageal metallic stents are indicated in the palliative treatment of malignant dysphagia [1]. The ones usually used are covered or partially covered. They have a low mortality rate directly associated (0.5-2%) [2]...

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Achondroplasia and Periodontal Disease - Molecular Testing Methods Case Report

Achondroplasia is an autosomal dominant genetic disease with its molecular mutation in gene encoding in type 3 of the receptor for fibroblast growth factor 3 (FGFR3). Although available literature describes..

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A Mild form of Familial Mediterranean Fever Associated with a Polymorphisms C.Nt 1588,-69G>

Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease caused by mutation(s) in the Mediterranean fever (MEFV, pyrinmarenostrin) gene. FMF is characterized by recurrent fever crisis combined..

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Abdominal Tumor Case Report

The ovarian teratoma is a tumor formed by pluripotent germina cells, benign or malign. In Surgical Clinic 1 there have been operated a lot of giant abdominal tumors...

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The Developing Patterns of Calibrated Implant Stability Quotients of Posterior Implants

Many surgical protocols were modified to improve dental implant primary stability for the ensurance of implant success. However, the conclusions of applying osteotome condensation technique could..

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Bilateral Ovarian Thecoma in a Postmenopausal Woman with Rapidly Progressed Severe Hyperandrogenism

Sex cord-stromal neoplasms of the ovary are an infrequent cause of androgen excess and virilization in women. We report a case of a 60 years old woman with rapidly progressive signs of virilization and indeterminate..

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Atypical Presentation of Acanthamoeba Keratitis- Case Report and Review of the Literature

The purpose is to present painless Acanthamoeba keratitis and to summarize actual literature data on this ocular infection. A 48-year-old women with a history of occasionally soft contact lens wear was referred to our hospital..

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Anesthetic Management of a Parturient with a History of Primary Spinal Malignant Melanoma

Background: Primary CNS malignant melanomas are quite rare as they account for 1% of all CNS tumors. The potential presence of spinal cord malignancies is worrisome when considering neuraxial techniques due to possible complications..

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Surgical Treatment for Iatrogenic Intrathoracic Subclavian Artery Aneurysm

Subclavian artery aneurysms (SAAs) are not common but with possible limb and life threatening complications...

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Infectious Aortitis Complicated by Type B Intramural Hematoma

An 83-year-old woman was admission due to intermittent fever for 1 week. Her temperature was 38.5°C, and chest X-ray demonstrated tortuosity of aorta with calcification of aortic arch. Her blood cultures subsequently all grew..

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Hypopyon as an Unusual Complication of Varicella Infection in a Girl with Atopic Dermatitis

Varicella-Zoster-Virus (VZV) infection, also known as chickenpox, is a very common childhood affliction manifesting primarily on the skin. Typical skin lesions are small itchy single standing vesicles on..

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Portosystemic Shunt for Treatment of Symptomatic Varices in Polycythemia Vera Patient: A Case Report

Myeloproliferative disorders are commonly associated with portal vein thrombosis, which can lead to extensive and symptomatic,..

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Indazole Synthetic Cannabinoids Intoxication Associated with Fatal Cardiac Complications: Two Case Reports

Usage of synthetic cannabinoids is associated with severe medical consequences and limited detectability in toxicology panels...

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A Rare Case of Amyand’S Hernia with Acute Appendicitis

Amyand’s hernia is an extremely rare and atypical hernia that is difficult to diagnose clinically characterized by the herniation of the appendix into the inguinal sac. The reported incidence is less than 1% of all adult..

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Hookah Use and COVID-19

A hookah (shisha, waterpipe) use may increase the risk of suffering from serious symptoms due to COVID-19. Like smoking, ..

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007 (Opioid Oligopoly and the Seven Deadly Sins)

The most common market structure in today’s market place is the oligopoly. An argument can be made that the few pharmaceutical companies who market, manufacture, distribute opioids worldwide can be defined as an “opioid...

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Toxin Positive Corynebacterium Diphtheriae Skin Ulcers in a Vaccinated Traveller

A 20 year old German volunteer presented in good general condition without fever to our outpatient department with cutaneous ulcers (Figure 1) on the lower limbs and swelling of the right lower leg. The patient had just returned from a one year stay in the Ivory Coast and mentioned several insect bites a week ago while still abroad...

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Angiosarcoma like Squamous Cell Carcinoma of the Oral Cavity— Report of Rare Subtype of Squamous Cell Carcinoma

Acantholytic Squamous Cell Carcinoma (SCC) of the oral cavity is an uncommon but well recognized variant of SCC and angiosarcoma like,..

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Dramatic Improvement in Dyspnea in A Non-Small Cell Lung Cancer Patient, Following Administration of Anti-IL-6R

Currently in most Lung Cancer cases in which there is tumor progression, the molecular approach is to search for new mutations, usually utilizing circulating free DNA. There are however cases where a trauma, such as an operation..

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Congenital Non-Union of Olecranum: A Review of Literature

Congenital non-union of the olecranum was first described by Habbe in 1942. A few authors described this anomaly in a very young patients. Only Two authors publicated the treatment of patella cubiti. Here, I document a brief review of literature.In this review, there are not figures and outcomes,..

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Nicolau Syndrome Due to Benzathine Penicillin Injection: (A Case Report)

Nicolau Syndrome(NS) is a rare complication of intramuscular injections, which is manifested by pain, edema, and livedoid discoloration of the skin immediately after injection. The pathophysiology of the disease is uncertain,..

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Association between Testosterone Levels and Clinical Markers of Atherosclerosis

To investigate the association between testosterone levels and parameters obtained from the clinical exercise stress test from 119 middle-aged Swedish men....

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An Unusual Case of Nasopharyngial Adenoid Cystic Carcinoma with Intracranial and Orbital Extension: A Challenge for Innovative Conformal Radiotherapy Techniques

Adenoid cystic carcinoma of nasopharynx is rare. When tumor is resectable, surgery alone or followed by radiotherapy is frequently used for treatment. In the other hand, when tumor is not resectable...

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A Study of the Prediction of Bowel Resection Due to Strangulated Small Bowel Obstruction

In this retrospective study, we aimed to assess the predictive factors for bowel resection due to Strangulated Small Bowel Obstruction (SSBO).

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Can Lung Ultrasound in Patients with Fever of Unknown Origin Detect Early Signs of COVID-19 Pneumonia?

The increasing interest in Lung Ultrasound (LUS) over the last years led to a great diffusion and better experience in using this technique, which became an essential tool for clinicians. During the current Coronavirus Disease 2019

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Severe Recurrent Hyponatremia and Acute Renal Failure Due to Shapiro’s Syndrome

Shapiro syndrome is a rare disorder defined by the clinical trial of relapsing episodes of hypothermia, hyperhidrosis and agenesis of the corpus callosum.....

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Synchronous Lung Cancer with Bone Metastasis and Rectal Cancer: A Case Report

The incidence of synchronous lung cancer and colorectal cancer is very rare. Therefore, physicians might lead to misdiagnosis as colorectal cancer with lung metastasis when lung lesion is found in a patient with colorectal cancer

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Preliminary Results of Fecal Microbiota Transplantation in Diarrhea-Predominant Irritable Bowel Syndrome: Case Series on 12 Patients

Irritable Bowel Syndrome (IBS) is associated with intestinal dysbiosis and it has been suggested Fecal Microbiota Transplantation (FMT) has a positive effect on the condition. In this preliminary study, we recruited 12 IBS patients with moderate to severe diarrhea (IBS-D) and assessed the clinical outcomes of single FMT.

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Postpartum Meningitis by Enterococcus Faecalis Secondary to Neuraxial Anesthesia

Meningitis is an infrequent and serious cause of postpartum fever that requires early diagnosis and treatment to prevent serious complications and to reduce the high mortality rate. Neuraxial anesthesia is a frequently used technique

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Advanced Esophagogastric Cancer after Bariatric Procedure

A 74-year-old man, non-smoker or alcoholic, underwent gastric bypass with stapled division of the stomach and Roux-en-Y gastrojejunostomy 20 years ago. A band was used to limit the emptying of the gastric pouch.

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Herpes Simplex Encephalitis in Medulloblastoma Patients: Case Report and Review of Literature

Encephalitis caused by Herpes Simplex Virus (HSV) and medulloblastoma are both fairly rare disorders with relatively poor prognoses. We experienced a case of HSV encephalitis (HSE) in which the patient presented 1 year after surgical resection and radiation therapy and 1 month after chemotherapy

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Superior Mesenteric Artery Syndrome Treated by Laparoscopic Duodenojejunostomy

Superior Mesenteric Artery syndrome (SMA Sd) is a very rare disease. It is suspected in the case of intestinal obstruction in severely underweight patients. When conservative management fails surgery becomes needed, with laparoscopic duodenojejunostomy being the best approach........

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